Results 171 to 180 of about 3,042,168 (292)

Cetyl All-<i>Trans</i>-Retinoate as a Lipidic ATRA Prodrug with Enhanced Anticancer and Chemosensitizing Activity. [PDF]

Int J Mol Sci
Moroz P, Muciek K, Świtalska M, Wietrzyk J, Lazar Z, Gliszczyńska A.   +5 more
europepmc   +1 more source

Next Generation Smart Implant Surfaces: Engineering Multifunctional Antimicrobial, Immunomodulatory and Regenerative Interfaces

Journal of Periodontal Research, EarlyView.
Natural‐inspired nano‐textured implant surfaces can be functionalised to modulate macrophage polarisation and local immune responses. This bioactive control promotes improved tissue integration and healing outcomes. ABSTRACT Dental implants rely on a stable and functional interface between the implant surface, surrounding tissues, and the oral ...
Roberto S. Pessoa, Lauren E. Steele, Mehvish Mumtaz, Denver P. Linklater, Neil M. O'Brien‐Simpson, Vladimir Baulin, Peter Kingshott, Roy Judge, Alastair J. Sloan, Elena P. Ivanova   +9 more
wiley   +1 more source

Retinoic acid alleviates manganese-induced neurotoxicity in SH-SY5Y cells via the Trim28/α-synuclein/H4K91ac epigenetic axis. [PDF]

Front Pharmacol
Ao C, Liu H, Ban R, Huang T, Xiao Y, Chen W, Feng Y, Zhao H, Ban J, Li J.   +9 more
europepmc   +1 more source

EXPRESSION OF A DOMINANT-NEGATIVE RETINOIC ACID RECEPTOR-GAMMA IN XENOPUS EMBRYOS LEADS TO PARTIAL RESISTANCE TO RETINOIC ACID

The administration of the teratogen retinoic acid (and other retinoids) to vertebrate embryos causes a range of developmental abnormalities. It remains to be shown how these teratogenic effects are mediated, and whether or not they reflect any ...

core  

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

Association of retinoids, retinoic acid receptors and epigenetics in breast cancer. [PDF]

Oncogene
Szymański Ł, Schenk T, Ławiński M, Brioli A, Zelent A.   +4 more
europepmc   +1 more source

AQP1 Corrects Acinar Cells’ Secretion Deficits in Sjögren's Disease

Oral Diseases, EarlyView.
ABSTRACT Introduction Sjögren's disease (SjD) is a systemic autoimmune disease characterized by dry mouth, dry eyes, and profound fatigue. Preclinical studies suggest that AQP1 gene expression in salivary glands corrects salivary hypofunction in preclinical and clinical studies of radiation‐induced xerostomia and improves salivary and lacrimal function
Paola Perez, Blake M. Warner, Youngmi Ji, Sandra Afione, Thomas J. F. Pranzatelli, Margaret E. Beach, Zohreh Khavandgar, Margie Grisius, Eileen Pelayo, Daniel Martin, NIDCD/NIDCR Genomics and Computational Biology Core, Alan N. Baer, John A. Chiorini   +12 more
wiley   +1 more source

Impaired retinoic acid receptor-γ signaling underlies a heritable form of urothelial keratinizing squamous metaplasia. [PDF]

HGG Adv
Fukushima K, Avery N, Desjardins J, Halliday BJ, Jenkins ZA, Porteous R, Morgan T, Parthasarathy P, Lau M, Vincent MW, Liu KJ, Twigg SRF, Robertson SP.   +12 more
europepmc   +1 more source

IL-6 Upregulates CD73 in Human Placental Mesenchymal Stem Cells to Promote ATRA-Induced NB4 Cell Differentiation in Acute Promyelocytic Leukemia. [PDF]

Cancer Med
Qi R, Zhang H, Wu Y, Ma Y, Luan X.
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source