Results 91 to 100 of about 50,187 (264)

A guide to bioinformatics for immunologists

Frontiers in Immunology, 2013
Bioinformatics includes a suite of methods, which are cheap, approachable, and many of which are easily accessible without any sort of specialized bioinformatic training. Yet, despite this, bioinformatic tools are under-utilized by immunologists. Herein,
Fiona Jane Whelan, Nicholas eYap, Michael G Surette, G. Brian eGolding, Dawn M. E. Bowdish   +4 more
doaj   +1 more source

Hole Scavenging and Photo-Stimulated Recombination of Electron-Hole Pairs in Aqueous TiO2 Nanoparticles [PDF]

arXiv, 2004
It is shown that 532 nm and 1064 nm laser photoexcitation of trapped electrons generated by 355 nm photolysis of aqueous titania (TiO2) nanoparticles causes rapid photobleaching of their absorbance band in the visible and near IR. This photobleaching occurs within the duration of the laser pulse (3 ns FWHM); it is caused by photoinduced electron ...
arxiv  

Scavenger Receptors [PDF]

, 2015
Scavenger receptors constitute a large family of evolutionally conserved protein molecules that are structurally and functionally diverse. Although scavenger receptors were originally identified based on their capacity to scavenge modified lipoproteins, these molecules have been shown to recognize and bind to a broad spectrum of ligands, including ...
John R. Subjeck, Xiaofei Yu, Paul B. Fisher, Xiang-Yang Wang, Chunqing Guo   +4 more
openaire   +3 more sources

Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma

Advanced Materials, EarlyView.
A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura, Alessio Malfanti, Ana I Matos, Carina Peres, Ana Armiñán, Aroa Duro‐Castaño, Inmaculada Conejos‐Sánchez, María Medel, Snežana Đorđević, Paula Carrascosa, Bárbara Carreira, Rita C Acúrcio, Helena Xavier‐Ferreira, Alberto Hernández‐Barranco, Elena Castellano, Esther Roselló, José C. Machado, Héctor Peinado, María J. Vicent, Helena F. Florindo   +19 more
wiley   +1 more source

HSL-knockout mouse testis exhibits class B scavenger receptor upregulation and disrupted lipid raft microdomains[S]

Journal of Lipid Research, 2012
There is a tight relationship between fertility and changes in cholesterol metabolism during spermatogenesis. In the testis, class B scavenger receptors (SR-B) SR-BI, SR-BII, and LIMP II mediate the selective uptake of cholesterol esters from HDL, which ...
María Emilia Casado, Lydia Huerta, Ana Isabel Ortiz, Mirian Pérez-Crespo, Alfonso Gutiérrez-Adán, Fredric B. Kraemer, Miguel Ángel Lasunción, Rebeca Busto, Antonia Martín-Hidalgo   +8 more
doaj  

Free Radical Scavenging and Cytotoxic Activities of Substituted Pyrimidines [PDF]

arXiv, 2020
A library of substituted pyrimidines was synthesized and evaluated for free radical scavenging, and in vitro cytotoxic activity in 3T3 cells. All compounds showed good free radical scavenging activity with IC50 values in the range of 42.9 + 0.31 to 438.3 3.3 {\mu}M as compared to the standard butylated hydroxytoluene having IC50 value of 128.83 2.
arxiv  

Mechanical and Light Activation of Materials for Chemical Production

Advanced Materials, EarlyView.
The actuation of stomata—referring to their opening and closing—is crucial for photosynthesis because it regulates gas exchange and water balance. Here, it is investigated if this life‐like property could enhance the photocatalytic properties of soft materials.
Luka Đorđević, Tyler J. Jaynes, Hiroaki Sai, Marianna Barbieri, Jacob E. Kupferberg, Nicholas A. Sather, Steven Weigand, Samuel I. Stupp   +7 more
wiley   +1 more source

Identification of scavenger receptors and thrombospondin‐type‐1 repeat proteins potentially relevant for plastid recognition in Sacoglossa

Ecology and Evolution, 2020
Functional kleptoplasty is a photosymbiotic relationship, in which photosynthetically active chloroplasts serve as an intracellular symbiont for a heterotrophic host.
Jenny Melo Clavijo, Silja Frankenbach, Cátia Fidalgo, João Serôdio, Alexander Donath, Angelika Preisfeld, Gregor Christa   +6 more
doaj   +1 more source

Multiple Routes for Glutamate Receptor Trafficking: Surface Diffusion and Membrane Traffic Cooperate to Bring Receptors to Synapses [PDF]

Science's STKE (electronic resource) : signal transduction knowledge environment 327 (21/03/2006) 13, 2007
Trafficking of glutamate receptors into and out of synapses is critically involved in the plasticity of excitatory synaptic transmission. Endocytosis and exocytosis of receptors have initially been thought to account alone for this trafficking. However, membrane proteins also traffic through surface lateral diffusion in the plasma membrane. We describe
arxiv  

Scavenger Receptor A: A New Route for Adenovirus 5

Molecular Pharmaceutics, 2009
Adenoviruses are common pathogens associated with respiratory diseases, gastrointestinal illnesses and/or conjunctivitis. Currently, this virus is used as a vector in gene therapy trials. The promise of viral gene therapy applications is substantially reduced because the virus is cleared by liver macrophages upon systemic administration.
Haisma, H, Boesjes, M, Beerens, A, van der Strate, B, Curiel, D, Plüddemann, A, Gordon, S, Bellu, A   +7 more
openaire   +3 more sources