Results 141 to 150 of about 49,849 (243)

Human CD36: Gene Regulation, Protein Function, and Its Role in Atherosclerosis Pathogenesis. [PDF]

Genes (Basel)
Rac M.
europepmc   +1 more source

Carrier‐Free Nanocapsule with Dual‐Target Capacity for Synergistically Restoring Inflammatory Microenvironment and Microbiota Dysbiosis in Colitis

Advanced Science, EarlyView.
This manuscript presents a carrier‐free nanomedicine PCNPs@PEG‐Man with dual‐targeting for IBD. It resists harsh intestinal conditions, reduces oxidative stress, enhances drug uptake and retention, modulates inflammation, and reshapes gut microbiota, offering a safe and effective IBD therapy.
Yingjie Chen, Yuhan Gao, Kaiyuan Huo, Zhaofan Jin, Wenchao Wang, Xingjie Zan, Yanlong Liu, Limeng Zhu, Jianfeng Yang   +8 more
wiley   +1 more source

Extracellular vesicles in atherosclerosis cardiovascular disease: emerging roles and mechanisms. [PDF]

Front Cardiovasc Med
Deng H, Qiu W, Zhang Y, Hua J.
europepmc   +1 more source

Role of Tunneling Nanotubes in Arachidonic Acid Transfer and Macrophage Function Reprogramming in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
Tunneling nanotubes facilitate the transfer of long‐chain fatty acids, primarily arachidonic acid, from tumor cells to macrophages, leading to lipid accumulation and activation of the PI3K‐Akt pathway. This drives a shift from the anti‐tumor CD5L⁺ phenotype to a pro‐tumor TREM2⁺ phenotype.
Meiru Chen, Shangyumeng Zhao, Xiaoli Xie, Jiaqi Wang, Miao Su, Lixian Zhang, Ruolin Cui, Dongqiang Zhao   +7 more
wiley   +1 more source

Cross one single body 49 tissues single-cell transcriptome reveals detailed macrophage heterogeneity during pig pregnancy. [PDF]

Front Immunol
Chen X, Lai C, Cai L, Huang L.
europepmc   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Orticumab: the potential to harness oxidized LDL to reduce coronary inflammation with plaque-targeted therapy. [PDF]

Curr Opin Lipidol
Farina CJ, Lu W, Nilsson J.
europepmc   +1 more source

Delivery of Molecular Hydrogen for Precision Immunomodulation: Mechanisms, Detection Methods, and Applications

Advanced Science, EarlyView.
This review focuses on the immunomodulatory mechanisms of molecular hydrogen, the recent detection methods, and the classification advanced molecular hydrogen delivery materials. It provides a detailed description of their applications in areas such as arthritis, chronic wounds, cardiovascular injury, tumors, and bacterial infections, aiming to enhance
Gangfeng Li, Hannan Cui, Ruixiao Fan, Guming Liu, Zishuo Hou, Yibo Zhang, Xuanming Che, Tengjiao Wang, Hongbo Wei, Peng Li   +9 more
wiley   +1 more source

Non-traditional lipid biomarkers in atherosclerotic cardiovascular disease: pathophysiological mechanisms and strategies to address residual risk. [PDF]

Front Endocrinol (Lausanne)
Wang C, Fu H, Xu H, Yang H, Min X, Wu W, Liu Z, Li D, Dong Y, Chen J.   +9 more
europepmc   +1 more source

Bionic Microneedle Patch Inspired by Drosophila Tarsal Paws Boosts Healing in Bacterial Infectious Stomatitis

Advanced Science, EarlyView.
Microneedle suction cup patches, prepared using bionic Drosophila tarsal claws, can effectively treat bacterial infectious stomatitis by rapidly and efficiently leveraging multiple effects, including antibacterial and anti‐inflammatory properties, promotion of vasodilation, and active mechanical contraction of the wound.
Jiaqi Qin, Cewen Hu, Xiaohong Ran, Huajing Zeng, Jie Zhang, Bin Liu, Zengjie Fan   +6 more
wiley   +1 more source