Results 171 to 180 of about 50,187 (264)

Bacterial Capture‐Killing Capsules with Remodeling Bone Immune Microenvironment for the Effective Treatment of Osteomyelitis

Advanced Science, EarlyView.
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang, Chang Shu, Chengwei Xu, Xingjie Zan, Shaoyin Wei, Chenglong Wang, Lianxin Li   +6 more
wiley   +1 more source

Unraveling the role of macrophages in diabetes: Impaired phagocytic function and therapeutic prospects. [PDF]

Medicine (Baltimore)
Rong B, Jiang H, Zhu W, Yang G, Zhou X, Lyu Z, Li X, Zhang J.   +7 more
europepmc   +1 more source

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Class B Scavenger Receptor CD36 as a Potential Therapeutic Target in Inflammation Induced by Danger-Associated Molecular Patterns. [PDF]

Cells
Baranova IN, Bocharov AV, Vishnyakova TG, Chen Z, Ke Y, Birukova AA, Yuen PST, Tsuji T, Star RA, Birukov KG, Patterson AP, Eggerman TL.   +11 more
europepmc   +1 more source

Low‐Coordination Configuration Single‐Atom Manganese Nanozymes for NIR‐Imaging‐Oriented Efficient Catalytic Oncotherapy

Advanced Science, EarlyView.
The manuscript designs a type of SA Mn‐CDs with low coordination Mn‐N2 configuration hydrothermally synthesized by chelating manganese atoms with ethylenediamine tetraacetic acid. SA Mn‐CDs not only have more active sites at the atomic level for high efficiently peroxidase‐like activity but also show excellent fluorescent ability at the cellular and ...
Peiwei Jin, Dandan Wang, Yijun Lu, Yong Qian, Chengyang Fang, Xiaoxiao Zhang, Junchao Qian, Songnan Qu, Hui Wang   +8 more
wiley   +1 more source

The Chromosome-level Genome of the Ctenophore Mnemiopsis leidyi A. Agassiz, 1865 Reveals a Unique Immune Gene Repertoire. [PDF]

Genome Biol Evol
Koutsouveli V, Torres-Oliva M, Bayer T, Fuß J, Grossschmidt N, Marulanda-Gomez AM, Jensen N, Gill D, Schmitz RA, Pita L, Reusch TBH.   +10 more
europepmc   +1 more source

Self‐Propelled In Situ Polymerized Nanoparticles Activating the STING Pathway for Enhanced Bladder Cancer Immunotherapy

Advanced Science, EarlyView.
A self‐propelled nanomedicine delivery system forms DMCU nanoparticles in the bladder via in situ polymerization of dopamine hydrochloride, Mn2+, cGAMP, and urease. The urease‐driven propulsion enhances retention and drug delivery. These nanoparticles activate the STING pathway, stimulating dendritic cells and T cells to boost anti‐bladder cancer ...
Lei Peng, Anguo Zhao, Rongkang Li, Yujun Liu, Daitian Tang, Dashi Deng, Qi Zhuang, Rui Liang, Shaohua Zhang, Song Wu   +9 more
wiley   +1 more source

The therapeutic potential of apigenin against atherosclerosis. [PDF]

Heliyon
Jiang X, Huang H.
europepmc   +1 more source

Customized Hydrogel System for the Spatiotemporal Sequential Treatment of Periodontitis Propelled by ZEB1

Advanced Science, EarlyView.
Through elaborate design, a biodegradable scaffold with excellent mechanical properties and suitability is fabricated, providing spatial support for subsequent physiological activities. The prepared GA‐HBC‐LIC hydrogel possesses sequential antibacterial, antioxidant, anti‐inflammatory and immunomodulatory functions, offering a suitable chemical and ...
Jiafei Chen, Xiaoxu Guan, Lina Chen, Bingzhu Zheng, Feiyu Li, Chao Fang, Yike Fu, Xiang Li, Huiming Wang, Yi Zhou   +9 more
wiley   +1 more source

Oxidized Low-Density Lipoprotein Induces Reactive Oxygen Species-Dependent Proliferation of Intestinal Epithelial Cells. [PDF]

Pharmaceuticals (Basel)
Gonzalez-Horta EE, Burgueno JF, Leiva MJ, Villavicencio C, Kawaguchi FI, Hazime H, Reyes F, Manrique-Suárez V, Parra NC, Abreu MT, Toledo JR.   +10 more
europepmc   +1 more source