Results 191 to 200 of about 50,187 (264)

Emerging Trends in DNA Nanotechnology-Enabled Cell Surface Engineering. [PDF]

JACS Au
Xiao F, Shen X, Tang W, Yang D.
europepmc   +1 more source

Multifunctional Biomimetic Nanotherapeutics for Anti‐Oxidative and Anti‐Inflammatory Synergistic Therapy of Corneal Neovascularization

Aggregate, EarlyView.
An anti‐inflammatory and antioxidant metal‐organic framework (MOF) nanoplatform was prepared via one‐pot self‐assembly. In vitro and in vivo studies demonstrated that the prepared MVPC nanoparticles can effectively scavenge overproduced reactive oxygen species at diseased sites, enhance IL‐10 secretion, and suppress VEGFA expression, offering a novel ...
Shundong Cai, Mengdie Li, Jinfa Ye, Mingyou Zhang, Jingbin Zhuang, Yuhang Cheng, Hongjin Li, Lang Ke, Xingyuan Wei, Yun Han, Huanhuan Liu, Gang Liu, Chengchao Chu   +12 more
wiley   +1 more source

Transcytosis of LDL Across Arterial Endothelium: Mechanisms and Therapeutic Targets. [PDF]

Arterioscler Thromb Vasc Biol
Bolanle IO, de Liedekerke Beaufort GC, Weinberg PD.   +2 more
europepmc   +1 more source

Hydrogel‐Based Smart Materials for Wound Healing and Sensing

Aggregate, EarlyView.
The graphical abstract illustrates the role of hydrogel‐based flexible materials in advancing biomedical applications, including wound healing, point‐of‐care diagnostics, smart patches, and wearable devices. Hydrogels are particularly promising in modern wound care due to their high‐water content, flexibility, and biocompatibility.
Thi Kim Ngan Duong, Thi Thuy Truong, Thi Nhat Linh Phan, Thi Xuan Nguyen, Vu Hoang Minh Doan, Truong Tien Vo, Jaeyeop Choi, Umapada Pal, Prodyut Dhar, Byeongil Lee, Junghwan Oh, Sudip Mondal   +11 more
wiley   +1 more source

Pro-Oxidative and Inflammatory Actions of Extracellular Hemoglobin and Heme: Molecular Events and Implications for Alzheimer's and Parkinson Disease. [PDF]

Biomol Ther (Seoul)
Campomayor NB, Kim HJ, Kim M.
europepmc   +1 more source

Synthesis, Optical and Singlet Oxygen Generation Properties of Phenazinone‐Based Photosensitizer with 5‐Formyl‐2‐Thienyl Substituents

Asian Journal of Organic Chemistry, EarlyView.
Phenazinone chromophore incorporating a carbonyl group into the skeleton is recently found to be a new‐type halogen‐atom‐free‐photosensitizer possessing superior ability in singlet oxygen (1O2) generation. In this work, we have designed and developed the derivative with two 5‐formyl‐2‐thienyl substituents which is expected to lead to improvement of the
Hiroto Tsuyama, Keiichi Imato, Yousuke Ooyama   +2 more
wiley   +1 more source

Systemic mechanisms of necrotic cell debris clearance. [PDF]

Cell Death Dis
Schuermans S, Kestens C, Marques PE.
europepmc   +1 more source

The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC‐derived neurons to amyloid beta and phosphorylated tau‐induced neuronal dysfunction

Alzheimer's &Dementia, EarlyView.
Abstract INTRODUCTION Human tau protein, composed of six brain‐specific isoforms, is a major driver of Alzheimer's disease (AD). The role of its isoforms however remains unclear and human AD models are scarce. METHODS We generated human MAPT– (tau–) knockout (KO) induced pluripotent stem cells (iPSC) using CRISPR/Cas9, differentiated these into ...
Sarah Buchholz, Mohamed Aghyad Al Kabbani, Michael Bell‐Simons, Lena Kluge, Cagla Cagmak, Jennifer Klimek, Natja Haag, Lukas C. Iohan, Audrey Coulon, Marcos R. Costa, Devrim Kilinc, Hans Zempel   +11 more
wiley   +1 more source

An update on ox-LDL-inducing vascular smooth muscle cell-derived foam cells in atherosclerosis. [PDF]

Front Cell Dev Biol
Guo J, Du L.
europepmc   +1 more source

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

Animal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran   +13 more
wiley   +1 more source