TREM-1 and TREM-2 as therapeutic targets: clinical challenges and perspectives. [PDF]
Sigalov AB.
europepmc +1 more source
Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota
Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog+8 more
wiley +2 more sources
Activation of receptor-independent fluid-phase pinocytosis promotes foamy monocyte formation in atherosclerotic mice. [PDF]
Ahn W+11 more
europepmc +1 more source
Brain endothelial cells as phagocytes: mechanisms and implications. [PDF]
Chang RT, Fisher MJ, Sumbria RK.
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Molecular Mechanisms of Alzheimer's Disease Induced by Amyloid-β and Tau Phosphorylation Along with RhoA Activity: Perspective of RhoA/Rho-Associated Protein Kinase Inhibitors for Neuronal Therapy. [PDF]
Ahn EH, Park JB.
europepmc +1 more source
Reduced Uptake of Oxidized Low-Density Lipoprotein by Macrophages Using Multiple Aptamer Combinations. [PDF]
Khongwichit S+6 more
europepmc +1 more source
Chemical Proteomics Reveals Human Off‐Targets of Fluoroquinolone Induced Mitochondrial Toxicity
A schematic overview of the adverse effects of Ciprofloxacin related to mitochondrial toxicity. AIFM1 plays a role in the MIA40‐mediated import into the IMS and oxidative folding of nuclear‐encoded proteins, including ETC complexes I and IV subunits. Ciprofloxacin disrupts the IMS import machinery, impairing ETC function.
Till Reinhardt+14 more
wiley +1 more source
The Ligand Binding Domain of the Cell Wall Protein SraP Modulates Macrophage Apoptosis and Inflammatory Responses in <i>Staphylococcus aureus</i> Infections. [PDF]
Sun H, Li RW, Wang TTY, Ding L.
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High‐intensity NIR radiation around 800 nm enables the manufacture of dry film resists (DFRs) using a combination of hexa‐arylbisimidazole (HABI) and N‐phenyl imino acetic acid. The mechanism is based on activated electron transfer processes supported by the respective product analysis.
Xianglong He+8 more
wiley +1 more source