Results 221 to 230 of about 54,333 (259)
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Hemoglobin and Heme Scavenger Receptors
Antioxidants & Redox Signaling, 2010Heme, the functional group of hemoglobin, myoglobin, and other hemoproteins, is a highly toxic substance when it appears in the extracellular milieu. To circumvent potential harmful effects of heme from hemoproteins released during physiological or pathological cell damage (such as hemolysis and rhabdomyolysis), specific high capacity scavenging ...
Nielsen MJ, Møller HJ, Moestrup SK.
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Macrophage scavenger receptors
Current Opinion in Lipidology, 1994Macrophage scavenger receptors are integral membrane proteins whose ability to bind and degrade modified LDL has implicated them in the process of atherosclerotic foam cell formation. Their ability to bind non-lipoprotein ligands suggests that they participate in other macrophage-associated host defense activities.
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Macrophage scavenger receptors and atherosclerosis
Trends in Cardiovascular Medicine, 1992The fatty streak is the earliest visible atherosclerotic lesion. Microscopically, this lesion consists of a subendothelial collection of macrophage foam cells that are characterized by their content of numerous lipid droplets. Investigations into the mechanisms responsible for foam cell formation have led to the identification of macrophage scavenger ...
H, Wu, K S, Moulton, C K, Glass
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Identification of the haemoglobin scavenger receptor
Nature, 2001Intravascular haemolysis is a physiological phenomenon as well as a severe pathological complication when accelerated in various autoimmune, infectious (such as malaria) and inherited (such as sickle cell disease) disorders. Haemoglobin released into plasma is captured by the acute phase protein haptoglobin, which is depleted from plasma during ...
Madsen, Mette; id_orcid 0000-0001-7241-6505 +6 more
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Scavenger receptor regulation and atherosclerosis
BioFactors, 2000AbstractAtherosclerosis and its complications, such as coronary heart disease, heart infarction and stroke, are the leading causes of death in the developed world. High blood pressure, diabetes, smoking and a diet high in cholesterol and lipids clearly increase the likelihood of premature atherosclerosis, albeit other factors, such as the individual ...
ZINGG JM, RICCIARELLI, ROBERTA, AZZI A.
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Collagenous macrophage scavenger receptors
Current Opinion in Lipidology, 1996Collagen, the most abundant protein in the human body, is a major constituent of extracellular matrix. Among macrophage membrane proteins, type I and II scavenger receptors and MARCO contain a collagenous domain. Analysis of type I and II receptor knockout mice and histochemical studies indicate that these proteins play roles in scavenger, adhesion and
T, Kodama +5 more
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Scavenger Receptors in the Pathogenesis of Viral Infections
Viral Immunology, 2022Scavenger receptors (SR) are not only pattern recognition receptors involved in the immune response against pathogens but are also important receptors exploited by different virus to enter host cells, and thus represent targets for antiviral therapy. The high mutation rates of viruses, as well as their small genomes are partly responsible for the high ...
Nora A. Fierro +4 more
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Current Opinion in Lipidology, 2004
This review will survey recent findings on the cholesterol transport and scavenger functions of scavenger receptor BI. Although scavenger receptor BI and CD36 bind many of the same ligands, these two receptors have very specific lipid transport functions: CD36 facilitates the uptake of long chain fatty acids and SR-BI mediates the transport of ...
Margery A, Connelly, David L, Williams
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This review will survey recent findings on the cholesterol transport and scavenger functions of scavenger receptor BI. Although scavenger receptor BI and CD36 bind many of the same ligands, these two receptors have very specific lipid transport functions: CD36 facilitates the uptake of long chain fatty acids and SR-BI mediates the transport of ...
Margery A, Connelly, David L, Williams
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Nihon rinsho. Japanese journal of clinical medicine, 2000
After the proposal of scavenger pathway hypothesis, a family of genes have been discovered. Here we show the precise properties of the first cloned scavenger receptor class A type I and II. Then the profiles of other members of scavenger receptors including lectin receptors are shown briefly.
T, Kohro +3 more
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After the proposal of scavenger pathway hypothesis, a family of genes have been discovered. Here we show the precise properties of the first cloned scavenger receptor class A type I and II. Then the profiles of other members of scavenger receptors including lectin receptors are shown briefly.
T, Kohro +3 more
openaire +1 more source