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Serotonin Receptors in Hippocampus [PDF]
The Scientific World Journal, 2012 Serotonin is an ancient molecular signal and a recognized neurotransmitter brainwide distributed with particular presence in hippocampus. Almost all serotonin receptor subtypes are expressed in hippocampus, which implicates an intricate modulating system,
Laura Cristina Berumen +3 more
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The Role of Serotonin Neurotransmission in Gastrointestinal Tract and Pharmacotherapy
Molecules, 2022 5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous system and peripheral structures, acting also as a hormone in platelets.
Tomasz Guzel, Dagmara Mirowska-Guzel
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Serotonin receptors in depression: from A to B [version 1; referees: 3 approved]
F1000Research, 2017 The role of serotonin in major depressive disorder (MDD) is the focus of accumulating clinical and preclinical research. The results of these studies reflect the complexity of serotonin signaling through many receptors, in a large number of brain regions,
Katherine M. Nautiyal, René Hen
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Serotonin, serotonin receptors and their actions in insects
Neurotransmitter, 2015 Serotonin is an ancient monoamine neurotransmitter, biochemically derived from tryptophan. It is most abundant in the gastrointestinal tract, but is also present throughout the rest of the body of animals and can even be found in plants and fungi. Serotonin is especially famous for its contributions to feelings of well-being and happiness.
Vleugels, Rut +2 more
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Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go
Nature, 2018 G-protein-coupled receptors (GPCRs) form the largest family of receptors encoded by the human genome (around 800 genes). They transduce signals by coupling to a small number of heterotrimeric G proteins (16 genes encoding different α-subunits).
Javier García-Nafría +2 more
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The role of 5-HT receptors in depression
Molecular Brain, 2017 Depression is a polygenic and highly complex psychiatric disorder that remains a major burden on society. Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), are some of the most commonly prescribed drugs worldwide.
Christine N. Yohn +2 more
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Cardiac Roles of Serotonin (5-HT) and 5-HT-Receptors in Health and Disease
International Journal of Molecular Sciences, 2023 Serotonin acts solely via 5-HT4-receptors to control human cardiac contractile function. The effects of serotonin via 5-HT4-receptors lead to positive inotropic and chronotropic effects, as well as arrhythmias, in the human heart.
J. Neumann +3 more
semanticscholar +1 more source
Nature Communications, 2023 Serotonin is a neurotransmitter that signals through 5-HT receptors to control key functions in the nervous system. Serotonin receptors are also ubiquitously expressed in various organs and have been detected in embryos of different organisms.
Sanjay Karki +7 more
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Frontiers in Cellular Neuroscience, 2022 Depression and anxiety are common, debilitating psychiatric conditions affecting millions of people throughout the world. Current treatments revolve around selective serotonin reuptake inhibitors (SSRIs), yet these drugs are only moderately effective at ...
Nikita Deo, Gregory Redpath
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European Journal of Medical Research, 2022 Background Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction and repetitive stereotyped behaviors.
Haowei Cao +4 more
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