Results 1 to 10 of about 197,299 (308)

Serotonin Receptors in Hippocampus [PDF]

open access: yesThe Scientific World Journal, 2012
Serotonin is an ancient molecular signal and a recognized neurotransmitter brainwide distributed with particular presence in hippocampus. Almost all serotonin receptor subtypes are expressed in hippocampus, which implicates an intricate modulating system,
Laura Cristina Berumen   +3 more
doaj   +5 more sources

Serotonin signaling regulates actomyosin contractility during morphogenesis in evolutionarily divergent lineages

open access: yesNature Communications, 2023
Serotonin is a neurotransmitter that signals through 5-HT receptors to control key functions in the nervous system. Serotonin receptors are also ubiquitously expressed in various organs and have been detected in embryos of different organisms.
Sanjay Karki   +7 more
doaj   +1 more source

Serotonin Receptor and Transporter Endocytosis Is an Important Factor in the Cellular Basis of Depression and Anxiety

open access: yesFrontiers in Cellular Neuroscience, 2022
Depression and anxiety are common, debilitating psychiatric conditions affecting millions of people throughout the world. Current treatments revolve around selective serotonin reuptake inhibitors (SSRIs), yet these drugs are only moderately effective at ...
Nikita Deo, Gregory Redpath
doaj   +1 more source

Autism-like behaviors regulated by the serotonin receptor 5-HT2B in the dorsal fan-shaped body neurons of Drosophila melanogaster

open access: yesEuropean Journal of Medical Research, 2022
Background Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction and repetitive stereotyped behaviors.
Haowei Cao   +4 more
doaj   +1 more source

Increased release of serotonin from rat primary isolated adult cardiac myofibroblasts

open access: yesScientific Reports, 2021
Elevated blood serotonin levels have been observed in patients with heart failure and serotonin has a role in pathological cardiac function. The serotonin receptor system was examined in adult rat isolated cardiac fibroblast and myofibroblast cells. This
Emiri Tarbit   +4 more
doaj   +1 more source

The Role of Serotonin Neurotransmission in Gastrointestinal Tract and Pharmacotherapy

open access: yesMolecules, 2022
5-Hydroxytryptamine (5-HT, serotonin) is a neurotransmitter in both the central nervous system and peripheral structures, acting also as a hormone in platelets.
Tomasz Guzel, Dagmara Mirowska-Guzel
doaj   +1 more source

Environment-Sensitive Fluorescence of 7-Nitrobenz-2-oxa-1,3-diazol-4-yl (NBD)-Labeled Ligands for Serotonin Receptors

open access: yesMolecules, 2021
Serotonin is a neurotransmitter that plays a crucial role in the regulation of several behavioral and cognitive functions by binding to a number of different serotonin receptors present on the cell surface.
Parijat Sarkar   +5 more
doaj   +1 more source

Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar purkinje cells: a lugaro cell to Purkinje cell synapse [PDF]

open access: yes, 2003
We recorded a novel fast GABAergic synaptic current in cerebellar Purkinje cells in rat brain slices using patch-clamp techniques. Because of a relatively low sensitivity to bicuculline, these currents can be recorded under conditions in which basket ...
Dean, I., Edwards, F.A., Robertson, S.J.
core   +3 more sources

The discovery, structure, and function of 5-HTR1E serotonin receptor

open access: yesCell Communication and Signaling, 2023
Serotonin (5-hydroxytryptamine, 5-HT) is a unique neurotransmitter which can regulate various biological processes by activating thirteen different receptors. These serotonin receptors are divided into seven different classes based on their structure and
Vinay Kumar Sharma, Y. Peng Loh
doaj   +1 more source

Enhanced sensitivity of postsynaptic serotonin-1A receptors in rats and mice with high trait aggression [PDF]

open access: yes, 2001
Individual differences in aggressive behaviour have been linked to variability in central serotonergic activity, both in humans and animals. A previous experiment in mice, selectively bred for high or low levels of aggression, showed an up-regulation of ...
Boer, Sietse F. de,   +5 more
core   +1 more source

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