Rethinking gonadotropin releasing hormone agonist suppression test: why it should be a gonadotropin releasing hormone antagonist suppression test. [PDF]
Munshi R, Coutu Nadeau LP, Dahan MH.
europepmc +1 more source
A flexible indium–gallium–zinc oxide field‐effect transistor platform on polyimide is developed for electrostatic cortisol detection. Wafer‐scale fabricated devices exhibit uniform electrical characteristics and maintain stable operation under mechanical bending.
Ngoc Thanh Ho +3 more
wiley +1 more source
Beyond the canonical view: steroid receptor network plasticity and mechanosensitive chromatin integration in breast cancer. [PDF]
García-García J +5 more
europepmc +1 more source
Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley +1 more source
Grand challenges in sex differences in immunology: problems the field must solve before biological sex can guide clinical practice. [PDF]
Flanagan KL, Kovats S.
europepmc +1 more source
This study aimed to determine the value of the National Clinical Database (NCD) risk calculator in predicting surgical outcomes and long‐term prognosis in patients undergoing resection for hepatocellular carcinoma (HCC). We retrospectively analyzed data from 210 patients with HCC who underwent initial hepatic resection, assessing the relationship ...
Mariko Tsukagoshi +8 more
wiley +1 more source
Binding Affinity Ranking at the Molecular Initiating Event (BARMIE): An open-source computational pipeline for the rapid screening of chemical interactions with steroid receptors from many species. [PDF]
Calahorro F +5 more
europepmc +1 more source
ABSTRACT Inflammatory bowel disease management has undergone a major transformation with the introduction of treat‐to‐target strategies and highly effective biologic and small‐molecule therapies. Although these advances have reduced the overall requirement for surgery, operative intervention remains essential for selected patients with ulcerative ...
Yoshiki Okita +4 more
wiley +1 more source
Estrogen Receptors and Enzymes Involved in Estrogen Synthesis as Breast Cancer Treatment Targets. [PDF]
Licznerska B +3 more
europepmc +1 more source
Autonomous AI‐Driven Design for Skin Product Formulations
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang +5 more
wiley +1 more source

