Results 161 to 170 of about 798,182 (300)

Problems in the use of chemical and functional nomenclatures for steroids in human physiology, biology and pharmacology. [PDF]

RSC Adv
Honour JW.
europepmc   +1 more source

Initial Stay Time and Work‐Rest Scheduling During Consecutive Heavy‐Intensity Workdays in Hot Environments in Young and Older Males

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Introduction This study examined initial stay times (IST), defined as the duration of uninterrupted work before core temperature approaches recommended safety limits (38.0°C, ~1.0°C above baseline), and the efficacy of work‐rest cycles during repeated heavy work across consecutive workdays in young and older males.
Glen P. Kenny, Gil Bourgois, Sarah M. Taggart, Kelli E. McCormick, James J. McCormick, Leonidas G. Ioannou, Fergus K. O'Connor   +6 more
wiley   +1 more source

Reply to Huang and Dong: Clarifying the interpretation of rapid steroid effects in social recognition. [PDF]

Proc Natl Acad Sci U S A
Aspesi D, Varatharajah A, Cioffi L, Diviccaro S, Caruso D, Becke N, Lalonde J, Perreault ML, Melcangi RC, MacLusky NJ, Choleris E.   +10 more
europepmc   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

Phthalates and Alternative Plasticizers in Female Reproductive Health and Pregnancy: From Epidemiological Evidence to Nuclear Receptor-Mediated Mechanisms: A State-of-the-Art Review. [PDF]

Biomolecules
Antoine A, Charnay C, Gallot D, Quinard R, Marceau G, Belville C, Richardson LS, Blanchon L, Menon R, Sapin V.   +9 more
europepmc   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

Limitations of Molecular Docking in Predicting the Selectivity of Selective Androgen Receptor Modulators (SARMs): A Comparative Study of YK11 and Ostarine Across Five Nuclear Receptors. [PDF]

Int J Mol Sci
Mihalev K, Iliev I, Agova N, Toshev N, Georgieva S.   +4 more
europepmc   +1 more source

Ocular and Systemic Findings in COL2A1 and COL11A1 Stickler Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Stickler syndrome is most commonly caused by variants in COL2A1 and COL11A1 genes. The purpose of this study was to describe genetic variants and phenotypes in COL2A1 and COL11A1 Stickler syndrome. We performed a retrospective genotype–phenotype evaluation of COL2A1 and COL11A1 Stickler syndrome subjects. Thirty‐two subjects with COL2A1 and 13
Aileen G. MacLachlan, Jessica A. Kraker, Denise J. Morgan, Lisa A. Schimmenti, M. Elizabeth Hartnett, Eileen S. Hwang   +5 more
wiley   +1 more source

The neurosteroid paradigm in perinatal depression: From pathophysiology to precision therapeutics. [PDF]

J Neuroendocrinol
Radonjić NV, Moon KC, Deligiannidis KM.
europepmc   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source