Results 21 to 30 of about 2,966,291 (347)

Localization of Receptors for Sex Steroids and Pituitary Hormones in the Female Genital Duct throughout the Reproductive Cycle of a Viviparous Gymnophiona Amphibian, Typhlonectes compressicauda

Animals, 2020
Reproduction in vertebrates is controlled by the hypothalamo-pituitary-gonadal axis, and both the sex steroid and pituitary hormones play a pivotal role in the regulation of the physiology of the oviduct and events occurring within the oviduct.
Claire Brun, Jean-Marie Exbrayat, Michel Raquet   +2 more
doaj   +1 more source

Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]

, 2016
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia, Lara, H. E., Recabarren, S. E., Roselli, C. E., Zubeldia Brenner, Lautaro   +4 more
core   +2 more sources

Block of NMDA receptor channels by endogenous neurosteroids: implications for the agonist induced conformational states of the channel vestibule [PDF]

, 2015
N-methyl-D-aspartate receptors (NMDARs) mediate synaptic plasticity, and their dysfunction is implicated in multiple brain disorders. NMDARs can be allosterically modulated by numerous compounds, including endogenous neurosteroid pregnanolone sulfate ...
A Malayev, A Sali, A Villarroel, AI Sobolevskii, AI Sobolevsky, AI Sobolevsky, AI Sobolevsky, BO Dubrovsky, C Beck, CE Weaver, CE Weaver Jr., CH Lee, CL Kussius, CT Smothers, CT Smothers, E Karakas, E Stastna, EE Baulieu, G Abdrachmanova, GQ Chen, H Havlikova, HR Chang, I Cerny, J Borovska, J Dai, J Zuo, JA Kemp, K Kashiwagi, K Vales, L Nowak, L Rambousek, L Vyklicky Jr., LM Arnostova, LP Wollmuth, M Benveniste, M Hollmann, M Horak, M Korinek, M Park-Chung, M Park-Chung, M Park-Chung, M Petrovic, M Sheng, M Xu, MA Larkin, MA Lomize, MA Lynch, MF Sanner, ML Mayer, MM Zarei, N Kashiwabuchi, NJ Sucher, PA Lapchak, R Kancheva, R Kazi, R Sprengel, RH Evans, S Schreier, SE Murthy, SF Traynelis, SH Mellon, SI Mota   +61 more
core   +1 more source

Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]

, 2006
Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Akwa Y, Baghai TC, Baker ER, Barrett-Connor E, Bicikova M, Bitran D, Bloch M, Brambilla F, Brambilla F, Brambilla F, Cornelius Schüle, Crawley JN, Dalton K, Daniela Eser, Dennerstein L, Dong E, Elena Romeo, Eser D, Evans RM, Fabian TJ, Freeman E, Freeman EW, Friess E, George MS, Goodyer IM, Guidotti A, Heydari B, Heydary B, Kita A, Koszycki D, Lawrie TA, Maayan R, Magill PJ, Majewska MD, Majewska MD, Majewska MD, Matsumoto K, Meieran SE, Melchior CL, Melchior CL, Mensah-Nyagan AG, Mienville JM, Monnet FP, Padberg F, Papadopoulos V, Paul SM, Purdy RH, Rainer Rupprecht, Reddy DS, Reddy DS, Reddy DS, Rodgers RJ, Romeo E, Rupprecht R, Rupprecht R, Schmidt PJ, Schule C, Schule C, Semeniuk T, Serra M, Serra M, Strohle A, Strohle A, Strohle A, Strous RD, Takebayashi M, Thomas C. Baghai, Tollefson GD, Trauger JW, Urani A, Uzunov DP, Uzunova V, Uzunova V, Uzunova V, Vanselow W, Wieland S, Wolkowitz OM, Wolkowitz OM, Wu FS, Zwanzger P   +79 more
core   +1 more source

Rodent Models of Non-classical Progesterone Action Regulating Ovulation

Frontiers in Endocrinology, 2017
It is becoming clear that steroid hormones act not only by binding to nuclear receptors that associate with specific response elements in the nucleus but also by binding to receptors on the cell membrane. In this newly discovered manner, steroid hormones
Melinda A. Mittelman-Smith, Lauren M. Rudolph, Margaret A. Mohr, Paul E. Micevych   +3 more
doaj   +1 more source

The coregulator exchange in transcriptional functions of nuclear receptors.

Genes & Development, 2000
Nuclear receptors (NR) comprise a family of transcription factors that regulate gene expression in a liganddependent manner. Members of the NR superfamily include receptors for steroid hormones, such as estrogens (ER) and glucocorticoids (GR), receptors ...
C. Glass, M. Rosenfeld
semanticscholar   +1 more source

Crystal structure of the mineralocorticoid receptor DNA binding domain in complex with DNA.

PLoS ONE, 2014
The steroid hormone receptors regulate important physiological functions such as reproduction, metabolism, immunity, and electrolyte balance. Mutations within steroid receptors result in endocrine disorders and can often drive cancer formation and ...
William H Hudson, Christine Youn, Eric A Ortlund   +2 more
doaj   +1 more source

Nuclear receptors in vascular biology [PDF]

, 2015
Nuclear receptors sense a wide range of steroids and hormones (estrogens, progesterone, androgens, glucocorticoid, and mineralocorticoid), vitamins (A and D), lipid metabolites, carbohydrates, and xenobiotics.
A Chawla, A McCurley, AA Hamers, AL Bookout, B Fisslthaler, BG Hoebel, C McCarthy, C Zhou, CH Lee, CK Glass, CK Huang, CT Lee, D Bishop-Bailey, D Bishop-Bailey, David Bishop-Bailey, DP Edwards, E Gerlach, F Akbiyik, FA Pereira, FL Wynne, FY Ali, G Pascual, I Dussault, I Spoletini, J He, J Qin, J Sonoda, J Xiang, K Spruiell, KE Swales, L Calza, L Li, L Piqueras, LA Moraes, LA Moraes, LJ Jonk, LR You, M Kaushik, M Matic, N Albermann, N Schafer, N Takamoto, Q Qin, R Zhao, S Asgary, S Chakrabarti, S Marino De, S Stein, SA Kliewer, V Zoete, W El-Sankary, WC Lau, X Wang, Y Ma, Y Sui, Y Sui, YW Hu   +56 more
core   +3 more sources

Physiology and Pathophysiology of Steroid Biosynthesis, Transport and Metabolism in the Human Placenta

Frontiers in Pharmacology, 2018
The steroid hormones progestagens, estrogens, androgens, and glucocorticoids as well as their precursor cholesterol are required for successful establishment and maintenance of pregnancy and proper development of the fetus.
W. Chatuphonprasert, K. Jarukamjorn, I. Ellinger   +2 more
semanticscholar   +1 more source

Endometriosis and nuclear receptors.

Human Reproduction Update, 2019
BACKGROUND Endometriosis is recognized as a steroid-dependent disorder; however, the precise roles of nuclear receptors (NRs) in steroid responsiveness and other signaling pathways are not well understood.
B. D. Yilmaz, S. Bulun
semanticscholar   +1 more source