Results 91 to 100 of about 579,792 (173)

Colonic smooth muscle cells and colonic motility patterns as a target for irritable bowel syndrome therapy: mechanisms of action of otilonium bromide

Therapeutic Advances in Gastroenterology, 2014
Otilonium bromide (OB) is a spasmolytic compound of the family of quaternary ammonium derivatives and has been successfully used in the treatment of patients with irritable bowel syndrome (IBS) due to its specific pharmacodynamic effects on motility ...
Jakub Rychter, Francisco Espín, Diana Gallego, Patri Vergara, Marcel Jiménez, Pere Clavé   +5 more
doaj   +1 more source

Tachykinin receptors: a radioligand binding perspective

, 1993
The last decade has witnessed major breakthroughs in the study of tachykinin receptors. The currently described NK-1, NK-2, and NK-3 receptors have been sequenced and cloned from various mammalian sources.
Dominic Geraghty (14737354), Mussap, CJ (15539585), Burcher, E (15539564)   +2 more
core  

Neurons bearing NK 3 tachykinin receptors in the guinea-pig ileum revealed by specific binding of fluorescently labelled agonists

, 1999
Neurons bearing NK 3 tachykinin receptors in the guinea-pig ileum revealed by specific binding of fluorescently labelled ...
Jan M Morgan (19465609), KM Jenkinson (19457143), John Furness (13070439), Bridget R Southwell (19187440)   +3 more
core  

Identification of the populations of enteric neurons that have NK1 tachykinin receptors in the guinea-pig small intestine

, 1998
Identification of the populations of enteric neurons that have NK1 tachykinin receptors in the guinea-pig small ...
AEG Lomax (19457056), PP Bertrand (19187362), John Furness (13070439)   +2 more
core  

Expression of two different tachykinin receptors in Xenopus oocytes by exogenous mRNAs

, 1987
Three tachykinins, substance P (SP), neurokinin A (NKA), and neurokinin B (NKB), have been isolated from the mammalian nervous system. In accordance with the presence of multiple tachykinins, the existence of multiple tachykinin receptors has been ...
S Nakanishi, Y Harada, M Kuno, K Nakayama, T Takahashi, Y Masu   +5 more
core   +1 more source

The role of tachykinin receptors in the control of respiration by the nucleus of the solitary tract

, 1999
The tachykinins are a family of peptides found extensively throughout the mammalian nervous system. In the brain stem, tachykinins, including substance P (SP) and neurokinin A (NKA), are present in areas involved in the integration of cardiovascular and ...
Mazzone, Stuart B (15926996)
core   +1 more source

Characterization of Tachykinin Receptors in Human and Rat Skin [PDF]

, 1993
Receptors for the tachykinin family of peptides were investigated in human and rat skin areas using quantitative receptor autoradiography and emulsion autoradiography with 125I-Bolton-Hunter substance P (125I-BH-substance P), a non-selective radioligand,
Deguchi, Masami
core  

Assays of 125I-Bolton-Hunter Substance P Binding Sites, Functional Sites of Tachykinin NK1 Receptor : Quantitative Receptor Autoradiographic Method [PDF]

, 1997
125I -Bolton-Hunter labeled tachykinins, substance P, neurokinin A, and eledoisin have been used as radioligands to differentiate multiple tachykinin receptors 11),12),30).
Niwa, Masami
core  

Characterization of receptors for two Xenopus gastrointestinal tachykinin peptides in their species of origin

, 2004
Two tachykinin peptides, bufokinin and Xenopus neurokinin A (X-NKA) were recently isolated from Xenopus laevis. In this study we investigated the tachykinin receptors in the Xenopus gastrointestinal tract.
Holmgren, Susanne,, Liu, L., Johansson, Ågot,, Burcher, E.   +3 more
core   +1 more source

Central tachykinin NK3 receptors in the inhibitory action on the rat colonic propulsion of a new tachykinin, PG-KII

, 1999
The inhibitory action of the natural selective tachykinin NK3 receptor agonist, PG-KII, (pGlu-Pro-Asn-Pro-Asp-Glu-Phe-Val-Gly-Leu-Met-NH2), on colonic propulsion was studied in rats after central administration.
BROCCARDO, Maria, Alessandra Tabacco, Maria Broccardo, IMPROTA, Giovanna, Giovanna Improta   +4 more
core   +1 more source