Results 81 to 90 of about 579,792 (173)

Tachykinin receptors in guinea-pig airways: characterization using selective ligands

, 1995
Tachykinin receptors in guinea-pig airways were examined using radioligand binding techniques in lung homogenates, and using isolated bronchial segments.
Solange Lavielle, Elizabeth Burcher, Xiang-Ping Zeng, John Strigas, Dominic P. Geraghty   +4 more
core   +1 more source

Targeting tachykinin receptors in neuroblastoma [PDF]

, 2017
Neuroblastoma is the most common extracranial tumor in children. Despite aggressive multimodal treatment, high-risk neuroblastoma remains a clinical challenge with survival rates below 50%.
Seiler, Marleen, Speleman, Franki, De Preter, Katleen, Bergmann, Andreas, Schramm, Alexander, Odersky, A., Schäfers, S., Astrahanseff, K., Speleman, F., De Preter, K., Bergmann, A., Althoff, Kristina, Althoff, K., Eggert, Angelika, Szymansky, Annabell, Henssen, Anton G, Schulte, J.H., Eggert, A., Henssen, A.G., Szymansky, A., Schulte, Johannes H, Struck, Joachim, Schäfers, Simon, Seiler, M., Beckers, A., Schramm, A., Beckers, Anneleen, Odersky, Andrea, Astrahanseff, Kathy, Struck, J.   +29 more
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Electroconvulsive shock increases tachykinin NK(1) receptors, but not the encoding mRNA, in rat cortex.

, 2001
Recent studies have suggested that the substance P (tachykinin NK(1)) receptor may be a pharmacological target for the treatment of mood disorders. Here, the effects of electroconvulsive shock on tachykinin NK(1) receptor gene expression in the rat brain
Qi Pei, Rowan Miller, Paul J Harrison, Philip W.J Burnet, Trevor Sharp, Louise J Lewis   +5 more
core   +1 more source

Neuropeptidergic regulation of neuromuscular signaling in larval zebrafish alters swimming behavior and synaptic transmission

iScience
Summary: Chemical synaptic transmission is modulated to accommodate different activity levels, thus enabling homeostatic scaling in pre- and postsynaptic compartments.
Holger Dill, Jana F. Liewald, Michelle Becker, Marius Seidenthal, Alexander Gottschalk   +4 more
doaj   +1 more source

Immunocytochemical distribution of NK-1 and NK-3 tachykinin receptors in isolated pancreatic acini of guinea pigs and rats

, 2005
In this study, we investigated the immunocytochemical distribution of NK-1 and NK-3 tachykinin receptors in guinea pig and rat isolated pancreatic acini. In dispersed acinar cells from guinea pig, immunofluorescence staining detected similar densities of
BROCCARDO, Maria, LINARI, Giorgio, AGOSTINI, SIMONA, Giusy Amadoro, Cinzia Severini, M. Teresa Ciotti, PETRELLA, CARLA, IMPROTA, Giovanna, Severini C, Improta G, Linari G, Broccardo M, Agostini S, Petrella C, Amadoro G, Ciotti MT   +15 more
core   +1 more source

G-Protein-Coupled Receptors: Next Generation Therapeutic Targets in Head and Neck Cancer?

Toxins, 2015
Therapeutic outcome in head and neck squamous cell carcinoma (HNSCC) is poor in most advanced cases. To improve therapeutic efficiency, novel therapeutic targets and prognostic factors must be discovered.
Takeharu Kanazawa, Kiyoshi Misawa, Yuki Misawa, Takayuki Uehara, Hirofumi Fukushima, Gen Kusaka, Mikiko Maruta, Thomas E. Carey   +7 more
doaj   +1 more source

Autoradiographic mapping of pulmonary NK1 and NK2 tachykinin receptors and changes after repeated antigen challenge in guinea pigs

, 1996
An autoradiographic technique was used to study the distribution of changes in pulmonary NK1 and NK2 receptors in guinea pig lung after repeated antigen challenge.
Manzini, S, Barnes, PJ, Mak, JCW, Zhang, XL, Astolfi, M, Evangelista, S, Judith C.W. Mak, Mara Astolfi, Stefano Manzini, Xiao-Ling Zhang, Stefano Evangelista, Peter J. Barnes   +11 more
core   +1 more source

Neurokinin receptors subserving bronchoconstriction

, 1995
Tachykinin receptor subtypes were initially defined using agonist potency ratios for the endogenous ligands substance P (SP), neurokinin (NK) A, and NKB. On this basis it was suggested that there are three tachykinin receptor subtypes.
James L. Ellis
core   +1 more source

Tachykinin-like peptides and their receptors - A review

, 1999
Tachykinin-like peptides have been identified in many vertebrate and invertebrate species. On the basis of the data reviewed in this paper, these peptides can be classified into two distinct subfamilies, which are recognized by their respective sequence ...
WENDY VAN POYER, Torfs, Herbert, ELFRIEDE SWINNEN, JOZEF VANDEN BROECK, ARNOLD DE LOOF, Swinnen, Elfriede, Vanden Broeck, Jozef, JEROEN POELS, Poels, Jeroen, Ferket, Kathelijne, Van Poyer, Wendy, HERBERT TORFS, KATHELIJNE FERKET, De Loof, Arnold   +13 more
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Decoding the molecular and structural determinants of the neurokinin A and Aβ1-42 peptide cross-interaction in the amyloid cascade pathway

iScience
Summary: Tachykinins are short neuropeptides, such as substance P and neurokinin B, that have been shown to interact with Alzheimer’s β-amyloid (Aβ) peptide.
Mohsen Habibnia, Eric Catalina-Hernandez, Mario Lopez-Martin, David Masnou-Sanchez, Alex Peralvarez-Marin   +4 more
doaj   +1 more source