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Tachykinins and their Receptors in Human Malignancies

Current Drug Targets, 2006
The possibility of links between psychosocial factors and cancer incidence and progression has generated considerable scientific and public interest. Tachykinins, including substance P, neurokinin A and B, hemokinin-1 and endokinins, are a family of neuropeptides, acting through three types of transmembrane G-protein coupled receptors denoted NK1, NK2 ...
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Tachykinin NK3 Receptor Antagonists

2004
A growing body of evidence suggests th at tachykinin NK3 receptors at both central and peripheral sites may contribute to the pathogenesis of a variety of diseases. Although the discovery of potent and selective nonpeptide NK3 receptor antagonists initially lagged behind the development of comparable molecules for NKl and NK2 receptors, work in this ...
Mazzone, Stuart B., Canning, B.J.
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The Nomenclature of Tachykinin Receptors

2004
The first part of this chapter briefly reviews the studies leading to identification of mammalian and nonmammalian tachykinins, and of their multiple receptors. The second part deals with the issue of nomenclature. This was first addressed in 1984 during a IUPHAR Satellite Meeting held in Maidstone.
R. Patacchini, C. A. Maggi
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Tachykinin receptors and tachykinin receptor antagonists

Journal of Autonomic Pharmacology, 1993
C. A. Maggi   +3 more
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Characterization of Tachykinin Receptors

Current Protocols in Pharmacology, 1999
AbstractThe mammalian tachykinin peptides are a family of neuropeptides characterized by a common C‐terminal amino acid sequence of the form Phe‐X‐Gly‐Leu‐Met‐NH2, where X is either Phe or Val. Tachykinin peptides have various biological activities, including excitation of both peripheral and central neurons, stimulation of smooth muscle contraction ...
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Tachykinin receptors and receptor subtypes.

Archives internationales de pharmacodynamie et de therapie, 1995
The tachykinins, substance P, neurokinin A and neurokinin B, are a family of neuropeptides widely distributed in the mammalian central and peripheral nervous system. In the peripheral nervous system, tachykinins released from peripheral endings of sensory nerves are responsible for the neurogenic inflammation phenomenon.
R, Patacchini, C A, Maggi
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Functional and molecular characterization of tachykinins and tachykinin receptors in the mouse uterus.

Biology of reproduction, 2005
Supported by grants from the National Health and Medical Research Council of Australia; the Royal Women's Hospital, Carlton, Victoria, Australia; the Medical Research Council, United Kingdom; and Ministerio de Educación y Ciencia (SAF2002-04080-CO2-01), Spain. E.P and F.M.P. contributed equally to this work.
Patak, Eva   +7 more
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Tachykinins and their Receptors

2008
Alessandro Lecci, Carlo Alberto Maggi
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Tachykinin Receptor Subtype

Annals of the New York Academy of Sciences, 1991
Y, Takano   +4 more
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Tachykinin receptors

1988
S. Lavielle   +9 more
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