Results 101 to 110 of about 10,636 (238)
ABSTRACT Objective Soluble receptor for advanced glycation end‐products (sRAGE) and soluble Toll‐like receptor 4 (sTLR4) are circulating pattern recognition receptor isoforms implicated in inflammatory regulation in type 2 diabetes mellitus (T2DM). This study examined the effects of supervised aerobic exercise training (AET) on circulating sRAGE, sTLR4,
Ryan K. Perkins +9 more
wiley +1 more source
The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers
Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang +45 more
wiley +1 more source
This graphical abstract illustrates how acute ischemic stroke may be accompanied by neuroendocrine‐immune dysregulation, represented by a low FT3/FT4 ratio and a high neutrophil‐to‐lymphocyte ratio, which together improve early identification of patients at risk for post‐ischemic stroke urinary tract infection.
Zhangyan Geng +8 more
wiley +1 more source
Delay in Diagnosis of Addison's Disease: A Case Report and Literature Review
Graphic highlighting the timeline of ED visits and admissions for the case patient. ABSTRACT Primary adrenal insufficiency is a rare disorder prone to delay in diagnosis after initial presentation. Multiple factors including a wide range of presentations, slow onset of symptoms, and other human factors may be contributing to challenges with the ...
Ishita Bhattacharya +2 more
wiley +1 more source
ABSTRACT Acute encephalopathy in patients with prolonged isotretinoin exposure should prompt careful assessment of undisclosed or non‐prescribed medication use. This case suggests a possible association between high cumulative isotretinoin exposure, frequent daily rizatriptan use, and acute encephalopathy, but does not establish a definitive drug–drug ...
Soheil Roshanzamiri +5 more
wiley +1 more source
Two lateral mouse brain sagittal sections labeled, respectively, for Lypd1 (A) and Kcnab3 (B). (A) Lypd1 labels positively cortical Layers 2 and 5 (less heavily), but only at limbic mesocortical sites, forming the limbic ring that separates the unlabeled isocortex (IsoCx) from the unlabeled hippocampal and olfactory allocortex (Hi, Sub, ERh; OlfCx ...
Luis Puelles, Elena Garcia‐Calero
wiley +1 more source
Our research establishes a hybrid feature selection and ensemble machine learning pipeline for the classification of euthyroid, hyperthyroid, hypothyroid, and subclinical hypo‐ and hyperthyroid disorders. Variance Threshold with Backward Feature Elimination attained nearly 100% accuracy, while SHAP and LIME clarified the significance of features and ...
Md. Minhajul Abedin +5 more
wiley +1 more source
Genetic landscape of patients with atypical absence status epilepticus: A systematic review
Abstract Atypical absence status epilepticus (AASE) is a rare subtype of nonconvulsive status epilepticus (NCSE), characterized by clouding of consciousness and continuous or fluctuating epileptiform activity, generally at a frequency below 3 Hz. Only sparse literature exists on the genetic conditions associated with it.
Maria Cristina Cioclu +2 more
wiley +1 more source

