Results 91 to 100 of about 10,636 (238)

The hypothalamic–pituitary–thyroid axis is intact in male Irs4 knockout mice

open access: yesEuropean Thyroid Journal
Objective: Loss of function mutations in the insulin receptor substrate 4 (IRS4) gene cause a rare form of X-linked congenital central hypothyroidism in boys and men.
Emilie Brûlé   +7 more
doaj   +1 more source

Body size of male Atlantic salmon (Salmo salar L.) at introduction of a 5‐week LD12:12 winter signal influences their decision to mature early or smoltify

open access: yesJournal of Fish Biology, EarlyView.
Abstract Sexual maturation of male Atlantic salmon post‐smolts (‘jacking’) is undesired in aquaculture and seems to occur due to the intensification in modern facilities. Maturation depends on internal and external factors (temperature, photoperiod, feed availability, energy levels, body size, genetic background) that act on the brain‐pituitary‐gonad ...
Enrique Pino‐Martinez   +5 more
wiley   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter   +4 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu   +2 more
wiley   +1 more source

Thyroid antibody positivity in pregnancy is associated with altered reproductive hormone concentrations and placental growth in Lewis rats

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Thyroid antibody positivity (TAb+) in pregnancy is associated with adverse pregnancy outcomes, but the mechanisms are unclear. This study developed a rodent model of TAb+ in pregnancy, induced prior to mating so that TAb+ exposure occurred throughout the pregnancy. TAb+ did not alter thyroid hormone concentrations and had minimal
Rebecca L. Brady   +11 more
wiley   +1 more source

Reassessing Radioactive Iodine Use After Thyroidectomy in Low‐Risk Differentiated Thyroid Cancer: A Systematic Review and Meta‐Analysis

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Routine radioactive iodine (RAI) after thyroidectomy in low‐risk differentiated thyroid cancer shows no clear benefit in reducing recurrence or improving survival. These findings support a selective, risk‐based approach, avoiding unnecessary treatment and potential adverse effects.
Maheen Asif   +5 more
wiley   +1 more source

Head Acceleration Event Probabilities During Standardised Contact Drills in Academy Men's Rugby League

open access: yesEuropean Journal of Sport Science, Volume 26, Issue 9, September 2026.
ABSTRACT This study investigated head acceleration event (HAE) probabilities between common contact‐drills in rugby league. Fifteen professional male academy players participated in three training sessions, completing standardised contact‐drills while wearing custom‐fitted iMGs, all sessions were filmed.
Ryan White   +9 more
wiley   +1 more source

Assessing Clinical Severity and Prognosis in Adolescents With Anorexia Nervosa and Atypical Anorexia Nervosa Using the Albumin‐Globulin Ratio

open access: yesEuropean Eating Disorders Review, Volume 34, Issue 5, Page 1193-1208, September 2026.
ABSTRACT Objective The albumin‐globulin ratio (AGR) is a biochemical marker reflecting nutritional and inflammatory status, with significant prognostic value in chronic conditions. This study examined its association with clinical/biochemical markers in adolescents with anorexia nervosa (AN) and atypical AN (AAN).
Eylem Şerife Kalkan   +5 more
wiley   +1 more source

Lower social participation and physical activity in patients with craniopharyngioma or CNS germ cell tumor: Their association with apathy

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 3, September 2026.
Abstract Aim This study aimed to compare social participation and physical activity in patients with craniopharyngioma or central nervous system germ cell tumor (CNS germ cell tumor) with those of healthy participants and examine their associations with social behavioral disorders.
Misa Komaki   +10 more
wiley   +1 more source

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