Results 131 to 140 of about 594,054 (285)

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis

International Journal of Dermatology, EarlyView.
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller, Helmut Beltraminelli, Wolf‐Henning Boehncke, Maximilian Böhm, Antonio Cozzio, Peter Häusermann, Ahmad Jalili, Antonios G. A. Kolios, Claudia Lang, Eva Loos, Christoph Schlapbach, Curdin Conrad   +11 more
wiley   +1 more source

Thyrotropin-releasing hormone (TRH) receptors. Localization by light microscopic autoradiography in rat brain using [3H][3-Me-His2]TRH as the radioligand

, 1985
Thyrotropin releasing hormone (TRH) is a putative neurotransmitter in both the central and peripheral nervous system. In the present report, we have used autoradiography coupled with densitometric analysis of tritium-sensitive film to investigate the ...
PW Mantyh, SP Hunt
core   +1 more source

Refining Residual Ischemic Stroke Risk in Anticoagulated Atrial Fibrillation Using Index Outpatient LA Diameter: The CHA2DS2‐VALa Score

Journal of Cardiovascular Electrophysiology, EarlyView.
In anticoagulated atrial fibrillation, residual ischemic stroke risk persists despite guideline‐directed therapy. In this single‐center cohort, an enlarged index outpatient left atrial diameter independently predicted stroke and improved risk stratification when added to CHA2DS2‐VA (CHA2DS2‐VALa), supporting a simple, clinically implementable ...
Sefa Erdi Ömür, Emin Koyun, Gülşen Genç Tapar, Kayıhan Karaman, Metin Karayakali, Ataç Çelik, Uğur Kulu, Yasin Taşkin   +7 more
wiley   +1 more source

Multicomponent structure of the thyrotropin receptor: relationship to Graves' disease.

, 1983
The thyrotropin receptor is proposed to contain both a glycoprotein and a ganglioside component. Monoclonal antibodies have been developed against soluble thyroid TSH receptor preparations and using Graves' lymphocytes.
Cohen JL, LACCETTI, PAOLO, Kohn LD, Aloj SM, Valente WA, Grollman EF   +5 more
core  

Association between thyroid feedback quantile‐based index and the risk of in‐hospital amputation in patients with diabetic foot ulcer

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims To investigate the relationship between the thyroid feedback quantile‐based index (TFQI) and the risk of amputation during hospitalization in patients with diabetic foot ulcers (DFU). Methods This single‐center retrospective study included 381 hospitalized patients with DFU and normal thyroid function.
Jiale Wang, Yujie Huang, Funeng Wang, Meiling Lao, Lijun Lan, Peiling Liang   +5 more
wiley   +1 more source

TSH induces insulin receptors that mediate insulin costimulation of growth in normal human thyroid cells

, 2000
The mitogenic/goitrogenic effects of thyrotropin (TSH) on human thyrocytes in vitro and in vivo depend on permissive comitogenic effects of insulin-like growth factors (IGFs), which are mimicked in vitro by the low-affinity binding of high ...
Dumont, Jacques Emile, Van Keymeulen, Alexandra, Roger, Pierre P.   +2 more
core   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec, B. Villumsen, K. R. van Straalen, H. H. van der Zee, S. Valiukevičienė, T. Tzellos, J. C. Szepietowski, A. Szegedi, D. M. L. Saunte, M. Romanelli, H. Raynal, F. Prignano, E. P. Prens, M. Podda, A. Nassif, A. Molina‐Leyva, Ł. Matusiak, A. V. Marzano, B. M. McGrath, A. I. Liakou, B. Kirby, L. Kemény, E. Just, D. Ioannidis, J. R. Ingram, R. E. Hunger, B. Horváth, P. Guillem, Ø. Grimstad, E. J. Giamarellos‐Bourboulis, M. Dolenc‐Voljč, V. Del Marmol, Z. Bukvić Mokos, V. Bettoli, F. Benhadou, F. G. Bechara, C. C. Zouboulis   +36 more
wiley   +1 more source

Body size of male Atlantic salmon (Salmo salar L.) at introduction of a 5‐week LD12:12 winter signal influences their decision to mature early or smoltify

Journal of Fish Biology, EarlyView.
Abstract Sexual maturation of male Atlantic salmon post‐smolts (‘jacking’) is undesired in aquaculture and seems to occur due to the intensification in modern facilities. Maturation depends on internal and external factors (temperature, photoperiod, feed availability, energy levels, body size, genetic background) that act on the brain‐pituitary‐gonad ...
Enrique Pino‐Martinez, Kristine F. Staveland, Mitchell S. Fleming, Pablo Balseiro, Cindy Pedrosa, Sigurd O. Handeland   +5 more
wiley   +1 more source

Metabolic Adaptations to Weight Loss in Obese Senior Dogs: Effects on Energy Expenditure, Protein Turnover, and Voluntary Physical Activity

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Implications of obesity and weight loss (WL) for energy and protein metabolism are not fully understood, particularly in senior dogs. This study evaluated changes in body composition, energy expenditure (EE), protein turnover (PT), and voluntary physical activity (VPA) in senior dogs in maintenance and after 10% and 20% WL.
Ticiane Giselle Bitencourt Freire, Jhennifer de Castro Fenerick, Ariel de Castro, Maria Eduarda Gonçalves Tozato, Stephanie de Souza Theodoro, Letícia Grazielle Pacheco, Camila Goloni, Caroline Paschoal, Vladimir Eliodoro Costa, Aulus Cavalieri Carciofi   +9 more
wiley   +1 more source

Photo-affinity labelling of the thyrotropin receptor

The thyrotropin (TSH) receptor is an important but poorly characterised component of the thyroid cell surface [l] and in this paper we describe an analysis of the receptor using affinity labelling [2].
Buckland, Paul Robert, Davies Jones, Eirian, Rickards, Carole R., Howells, Rogers D., Rees Smith, Bernard   +4 more
core   +1 more source