Results 131 to 140 of about 20,737 (301)

Erg currents support electrical bursting in murine anterior pituitary corticotrophs

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Anterior pituitary corticotrophs are a central component of the hypothalamic‐pituitary‐adrenal (HPA) axis that controls the release of glucocorticoids from the adrenal gland in response to stress. The hypothalamic secretagogue corticotrophin releasing hormone (CRH) promotes electrical bursting of mouse anterior pituitary ...
Sooraj V. Nair   +5 more
wiley   +1 more source

Taste and Smell Disturbances Associated With Secondary Adrenal Insufficiency: A Case Report

open access: yesJournal of General and Family Medicine, Volume 27, Issue 4, July 2026.
ABSTRACT Background Adrenal insufficiency often presents with nonspecific symptoms, impeding early diagnosis. Taste and smell disturbances are rarely recognized as presenting features. Case Presentation We report the case of a 54‐year‐old man with a 3‐month history of persistent taste and smell disturbances accompanied by fatigue, loss of appetite ...
Takanori Izumi   +8 more
wiley   +1 more source

Vitamin‐Responsive Disorders: From Molecular Basis to Clinical Presentation and Therapy

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT Vitamin‐dependent cofactors are essential for numerous metabolic reactions, and defects affecting their uptake, conversion, utilisation, or regeneration constitute a heterogeneous group of inherited metabolic disorders (IMDs). Although dietary vitamin intake is sufficient to sustain coenzyme synthesis in healthy individuals, it is insufficient
Cécile Acquaviva   +5 more
wiley   +1 more source

Developmental Patterns of English Alphabet Knowledge in Chinese–English Emergent Bilingual Children

open access: yesReading Research Quarterly, Volume 61, Issue 3, July/August/September 2026.
The graphical abstract compares the developmental patterns of alphabet knowledge between Chinese‐English bilingual children and established monolingual norms. The study highlights a distinct developmental pattern, emphasizing the need for alphabet instruction that accounts for specific cultural and linguistic contexts for bilingual children.
Somin Park
wiley   +1 more source

Levothyroxine Treatment During Pregnancy: A Metabolomics Study

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.
ABSTRACT Levothyroxine is one of the most prescribed drugs during pregnancy. Our aim was to determine levothyroxine treatment‐associated changes in the metabolite profiles and link these to the health of the newborn. Metabolite profiles of 118 levothyroxine‐treated and 118 healthy control pregnancies were determined with nuclear magnetic resonance ...
Olli Kärkkäinen   +3 more
wiley   +1 more source

Intramyocardial gene silencing by interfering RNA [PDF]

open access: yes
RNAi is a widely used methodology for gene silencing. The action mechanism of siRNA molecules has been well studiedin recent years, and the technique has been optimized in terms of safety and effectiveness. Cardiovascular diseases havea high incidence in
Brea, María Soledad   +2 more
core  

Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis

open access: yesBJU International, Volume 138, Issue 1, Page 33-44, July 2026.
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon   +3 more
wiley   +1 more source

NASA Workshop on Biological Adaptation [PDF]

open access: yes
A workshop was convened to review the current program in Space Biology Biological Adaptation Research and its objectives and to identify future research directions.
Morey-Holton, Emily, Tischler, Marc
core  

The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]

open access: yes
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K   +3 more
core  

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