Results 221 to 230 of about 594,054 (285)

Targeting Peptidergic Systems for Melanoma Treatment. [PDF]

Cancers (Basel)
Sánchez ML, Mehboob R, Coveñas R.
europepmc   +1 more source

Endocrine complications of COVID-19: diabetes, musculoskeletal, thyroid, pituitary, adrenal, and gonadal disorders. [PDF]

J Endocr Soc
Asadipooya K, Sriramula S.
europepmc   +1 more source

Traditional Chinese Medicine as an Adjunct in Hyperthyroidism Management: A Narrative Review of Pathophysiology, Proposed Mechanisms, and Clinical Evidence. [PDF]

Int J Gen Med
Liu Z, Chen C, Yu S, Jin X, Sheng L, YanMu MR, Gao J, Lu J, Lei T.   +8 more
europepmc   +1 more source

Extracellular Matrix-Mediated Neuroendocrine Control of the Thymus.

Neuroimmunomodulation
Brito-Moreira J, Herculano EA, Savino W.
europepmc   +1 more source

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Thyrotropin binding specificity for the thyrotropin receptor

Journal of Endocrinological Investigation, 1995
Recently, highly purified bovine thyrotropin (bTSH) of pituitary origin, as well as recombinant human (h) TSH free of lutropin (LH) contamination, has been reported to activate the LH/choriogonadotropin receptor (LH/CGR). These data challenge the concept of TSH specificity for its own receptor.
Y, Nagayama, H, Yamasaki, A, Takeshita, H, Kimura, K, Ashizawa, N, Yokoyama, S, Yamashita, B, Rapoport, S, Nagataki   +8 more
openaire   +2 more sources

Thyrotropin receptor processing and interaction with thyrotropin

Biochemical and Biophysical Research Communications, 1990
In vitro transcription/translation, using rat thyrotropin receptor cDNA, results in the formation of nonglycosylated proteins able to bind thyrotropin, one of which approximates the 87 Kd size predicted for the receptor. In the presence of canine pancreatic microsomal membranes, putative glycosylation sites are modified as evidenced by digestion with ...
T, Akamizu, S, Kosugi, L D, Kohn
openaire   +2 more sources

Autoantibodies to the Thyrotropin Receptor

Endocrine Reviews, 1988
This review considers recent developments in our understanding of the properties of TRAb, particularly measurement of the antibodies and their sites of action and synthesis. Two new assay methods have allowed considerable improvements in the sensitivity, specificity, precision, and ease of measuring TRAb.
B, Rees Smith, S M, McLachlan, J, Furmaniak   +2 more
openaire   +2 more sources

The Thyrotropin Receptor

1995
This chapter has outlined the complex process required for thyroid growth and function. Both events are regulated by TSHR via a multiplicity of signals, with the aid of and requirement for a multiplicity of hormones that regulate the TSHR via receptor cross-talk: insulin, IGF-I, adrenergic receptors, and purinergic receptors.
L. D. Kohn, H. Shimura, Y. Shimura, A. Hidaka, GIULIANI, Cesidio, NAPOLITANO, Giorgio, M. Ohmori, G. Laglia, M. Saji   +8 more
openaire   +3 more sources

Thyrotropin receptor mutations as a tool to understand thyrotropin receptor action

Journal of Molecular Medicine, 2001
A large number of mutations have been identified in the thyrotropin (TSH) receptor (TSHR) gene causing human diseases. Toxic thyroid nodules are frequently associated with somatic constitutively activating TSHR mutations. Autosomal dominant non-autoimmune hyperthyroidism is caused by activating TSHR germline mutations.
P, Wonerow, S, Neumann, T, Gudermann, R, Paschke   +3 more
openaire   +2 more sources

Effects of Thyrotropin-Releasing Hormone in Depression. [PDF]

Lancet, The, 1972
Ten euthyroid women with unipolar depression were treated with a single injection of thyrotropin-releasing hormone (T.R.H.) and a single injection of saline in a double-blind, crossover comparison. T.R.H.
G R Breese, G R Breese, I C Wilson
exaly   +2 more sources