Results 11 to 20 of about 185,186 (308)

Role of transforming growth factor-β1 in breast carcinogenesis [PDF]

Archive of Oncology, 2006
The main objective of this presentation is to review current knowledge regarding molecular mechanisms of Transforming Growth Factor-β1(TGF-ß1) action in breast carcinogenesis.
Ivanović Vesna, Krtolica Koviljka, Krajnović Milena, Dimitrijević Bogomir   +3 more
doaj   +1 more source

TGFBR3 (transforming growth factor, beta receptor III) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on TGFBR3 (transforming growth factor, beta receptor III), with data on DNA, on the protein encoded, and where the gene is implicated.
Gatza, CE, Blobe, GC
openaire   +2 more sources

Expression of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ in the lung tissue of obese mice and the effect of rosiglitazone on proinflammatory cytokine expressions in the lung tissue [PDF]

Korean Journal of Pediatrics, 2013
PurposeWe investigated the mRNA levels of peroxisome proliferator-activated receptor (PPAR)-α, PPAR-γ, adipokines, and cytokines in the lung tissue of lean and obese mice with and without ovalbumin (OVA) challenge, and the effect of rosiglitazone, a PPAR-
Seung Lok Ryu, Jae Won Shim, Duk Soo Kim, Hye Lim Jung, Moon Soo Park, Soo-Hee Park, Jinmi Lee, Won-Young Lee, Jung Yeon Shim   +8 more
doaj   +1 more source

Reference gene validation for the relative quantification of cannabinoid receptor expression in human odontoblasts via quantitative polymerase chain reaction

Journal of Oral Biology and Craniofacial Research, 2022
Objective: The aim of this study was to identify and validate the reference genes in cultured human odontoblasts to quantify their cannabinoid receptor transcripts.
Laura M. Navarro-Saiz, Lilia J. Bernal-Cepeda, Felipe García-Jiménez, Deisy Abril, Jaime E. Castellanos   +4 more
doaj   +1 more source

The Effect of Alpha-Tocopherol on the Expression of Epidermal Growth Factor Receptor and Transforming Growth Factor Beta Genes in Three Developmental Stages of Echinococcus granulosus

Iranian Journal of Parasitology, 2020
Background: In recent decades platyhelminths have been used as model organisms to address some of the fundamental questions related to the growth and development of animal organisms. Epidermal Growth Factor Receptors (EGFR) and Transforming Growth Factor
Seyyed Jafar NOSRATABADI, Nasim HAYATI ROODBARI, Mohammad Hossein MODARRESI, Alireza FARSINEJAD, Majid FASIHI HARANDI   +4 more
doaj   +1 more source

TGFβ signaling pathways in human health and disease

Frontiers in Molecular Biosciences, 2023
Transforming growth factor beta (TGFβ) is named for the function it was originally discovered to perform-transformation of normal cells into aggressively growing malignant cells. It became apparent after more than 30 years of research, however, that TGFβ
Pei-Yu Chen, Lingfeng Qin, Michael Simons, Michael Simons   +3 more
doaj   +1 more source

Inhibition of Hsp90 Counteracts the Established Experimental Dermal Fibrosis Induced by Bleomycin

Biomedicines, 2021
Our previous study demonstrated that heat shock protein 90 (Hsp90) is overexpressed in the involved skin of patients with systemic sclerosis (SSc) and in experimental dermal fibrosis.
Hana Štorkánová, Lenka Štorkánová, Adéla Navrátilová, Viktor Bečvář, Hana Hulejová, Sabína Oreská, Barbora Heřmánková, Maja Špiritović, Radim Bečvář, Karel Pavelka, Jiří Vencovský, Jörg H. W. Distler, Ladislav Šenolt, Michal Tomčík   +13 more
doaj   +1 more source

Severe aortic and arterial aneurysms associated with a TGFBR2 mutation. [PDF]

, 2007
BACKGROUND: A 24-year-old man presented with previously diagnosed Marfan\u27s syndrome. Since the age of 9 years, he had undergone eight cardiovascular procedures to treat rapidly progressive aneurysms, dissection and tortuous vascular disease involving ...
A De Paepe, B Loeys, BL Loeys, CS Ki, Dianna M Milewicz, DM Milewicz, E Disabella, G Collod, H Dietz, H Pannu, Hariyadarshi Pannu, HC Dietz, J Furlong, Joseph S Coselli, K Kainulainen, LC Ades, Scott A LeMaire, SN Hasham, Stacey A Carter, T Mizuguchi, VA McKusick, Van Tran-Fadulu   +21 more
core   +1 more source

Soluble endoglin, transforming growth factor-Beta 1 and soluble tumor necrosis factor alpha receptors in different clinical manifestations of preeclampsia. [PDF]

PLoS ONE, 2014
Despite intensive research, the etiopathogenesis of preeclampsia (PE) remains uncertain. Inflammatory and angiogenic factors are thought to play considerable roles in this disease.
Luiza O Perucci, Karina B Gomes, Letícia G Freitas, Lara C Godoi, Patrícia N Alpoim, Melina B Pinheiro, Aline S Miranda, Antônio L Teixeira, Luci M Dusse, Lirlândia P Sousa   +9 more
doaj   +1 more source

Human activin-A is expressed in the atherosclerotic lesion and promotes the contractile phenotype of smooth muscle cells [PDF]

, 1999
Activin is a member of the transforming growth factor-beta superfamily, and it modulates the proliferation and differentiation of various target cells. In this study, we investigated the role of activin in the initiation and progression
Achterberg, T.A.E. (Tanja) van, Aken, B.E. (Benien) van, Engelse, M.A. (Marten), Neele, J.M., Pannekoek, H. (Hans), Schaik, R.H.N. (Ron) van, Vries, C.J.M. (Carlie) de   +6 more
core   +3 more sources