Results 61 to 70 of about 89,614 (169)
Pro‐tumorigenic Effects of Transforming Growth Factor Beta 1 in Canine Osteosarcoma
Background Transforming growth factor beta 1 (TGFβ1) is a pleiotropic cytokine that contributes to reparative skeletal remodeling by inducing osteoblast proliferation, migration, and angiogenesis.
R.F. Portela +7 more
doaj +1 more source
The Role of the TGF-β Coreceptor Endoglin in Cancer
Endoglin (CD105) is an auxiliary membrane receptor of transforming growth factor beta (TGF-β) that interacts with type I and type II TGF-β receptors and modulates TGF-β signaling.
Eduardo Pérez-Gómez +5 more
doaj +1 more source
Transforming growth factor beta receptor II polymorphisms are associated with Kawasaki disease
Transforming growth factor beta receptor 2 (TGFBR2) is a tumor suppressor gene that plays a role in the differentiation of striated cells and remodeling of coronary arteries. Single nucleotide polymorphisms (SNPs) of this gene are associated with Marfan syndrome and sudden death in patients with coronary artery disease.
Yu Mi Choi +6 more
openaire +3 more sources
Transforming growth factor-beta receptor expression in human cornea.
Limbal basal cells and corneal endothelial cells appear to be inhibited in the G1 phase of the cell cycle. As a preliminary to determining whether transforming growth factor-beta (TGF-beta) might mediate this inhibition, investigation was made to determine whether human corneal and limbal cells express TGF-beta receptor types I (RI), II (RII), and III (
N C, Joyce, J D, Zieske
openaire +1 more source
Adult Neural Stem Cells (aNSCs) in the ventricular-subventricular zone (V-SVZ) are largely quiescent. Here, we characterize the mechanism underlying the functional role of a cell-signalling inhibitory protein, LRIG1, in the control of aNSCs proliferation.
Stephanie Ouzikov +10 more
doaj +1 more source
Transforming growth factor beta receptor II (TGFBR2) promoter region polymorphism [PDF]
Sora Yasri, Viroj Wiwanitkit
openaire +2 more sources
Transforming growth factor-beta superfamily members in the pathogenesis of pulmonary arterial hypertension [PDF]
Pulmonary arterial hypertension (PAH) is a devastating and rapidly progressing disease that induces substantial pulmonary vascular remodeling. The pathologic changes especially in pulmonary microvasculature result in progressive increases in the mean ...
Jerkić Mirjana
doaj
Functional Analysis of Transforming Growth Factor-.BETA. type II Dominant Negative Receptor.
The transforming growth factor-beta (TGF-beta) is a multifunctional homodimeric protein with an apparent molecular weight of 25 KDa. TGF-beta transduces signals by forming heteromeric complexes of their type-I (T beta R-I) and type-II (T beta R-II) serin/threonine kinase receptors.
openaire +3 more sources
El factor de crecimiento transformante beta (TGF-beta) es una familia de proteínas que incluye al TGF-beta, activinas y a la proteína morfogénica de hueso (BMP, por sus siglas en inglés), citocinas que son secretadas y se relacionan estructuralmente en ...
Francisco Javier Gálvez-Gastélum +2 more
doaj
To study transforming growth factor-beta1 (TGF-beta1) autoproduction in keloid fibroblasts and the regulation effect of blocking TGF-beta intracellular signaling on rhTGF-beta1 autoproduction.Keloid fibroblasts cultured in vitro were treated with either rhTGF-beta1 (5 ng/ml) or recombinant adenovirus containing a truncated type II TGF-beta receptor ...
Wei, Liu +7 more
openaire +1 more source

