Results 61 to 70 of about 214,767 (219)
Journal of Translational Medicine, 2012 Background Dovitinib is a receptor tyrosine kinase (RTK) inhibitor targeting vascular endothelial growth factor receptors, fibroblast growth factor receptors and platelet-derived growth factor receptor β. Dovitinib is currently in clinical trials for the
Chen Zhi-Yuan +9 more
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Armaghane Danesh Bimonthly Journal, 2019 Background & aim: The vascular endothelial growth factor of the tumor, which binds to its receptors at the level of endothelial cells, plays an important role in vascular permeability and tumor angiogenesis.
M Farzaneh Behelgardi +3 more
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Кардиоваскулярная терапия и профилактика, 2017 Aim. To evaluate diagnostic significance of the type A vascular endothelial growth factor (VEGF-A) and its receptors type 1 and 2 (VEGF-R1 and VEGF-R2) in primary mitral valve prolapse (MVP) patients.Material and methods. Totally, 83 MVP patients studied:
A. V. Yagoda +2 more
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Technology in Cancer Research & Treatment, 2020 Background: Association of drugs acting against different antiangiogenic mechanisms may increase therapeutic effect and reduce resistance. Noninvasive monitoring of changes in the antiangiogenic response of individual tumors could guide selection and ...
Michele Lamuraglia MD, PhD +8 more
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Inhibition of the tyrosine phosphatase SHP-2 suppresses angiogenesis in vitro and in vivo [PDF]
, 2007 Endothelial cell survival is indispensable to maintain endothelial integrity and initiate new vessel formation. We investigated the role of SHP-2 in endothelial cell survival and angiogenesis in vitro as well as in vivo.
Groesser, Leopold +8 more
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The Role of Angiogenesis in Human Non-Hodgkin Lymphomas
Neoplasia: An International Journal for Oncology Research, 2013 The role of angiogenesis in the growth of lymphomas and survival of patients with leukemias and other hematological malignancies has become evident since 1994. Angiogenic factors, such as vascular endothelial growth factor and its receptors together with
Domenico Ribatti +4 more
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Interleukin-12 Inhibits Tumor Growth in a Novel Angiogenesis Canine Hemangiosarcoma Xenograft Model
Neoplasia: An International Journal for Oncology Research, 2004 We established a canine hemangiosarcoma cell line derived from malignant endothelial cells comprising a spontaneous tumor in a dog to provide a renewable source of endothelial cells for studies of angiogenesis in malignancy. Pieces of the hemangiosarcoma
Nasim Akhtar +6 more
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Exploring the dermal immune and angiogenic responses to Schistosoma mansoni [PDF]
, 2011 Schistosoma mansoni is a parasitic helminth which gains access to the host’s vascular system by penetrating and migrating through the skin in search of a blood vessel.
Aynsley, Sarah Amelia
core
Notch1 signaling in the hepatic microcirculation and chronic liver disease [PDF]
, 2013 The Notch signaling pathway is an evolutionary conserved pathway that plays essential roles during vascular development and in the regulation of normal and pathological angiogenesis in the adulthood.
Rothweiler, Sonja
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Anti-angiogenic therapies for advanced esophago-gastric cancer
Indian Journal of Medical and Paediatric Oncology, 2014 Neo-vascularization is a vital process for tumor growth and development which involves the interaction between tumor cells and stromal endothelial cells through several growth factors and membranous receptors which ultimately activate pro-angiogenic ...
Elisa Fontana +2 more
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