Results 21 to 30 of about 14,916 (199)
Detection of bladder cancer using voided urine sample and by targeting genomic VPAC receptors
Indian Journal of Urology, 2021 Introduction: Cells exfoliated into urine from the bladder can help to diagnose the cancer. The objective of this study was to validate the hypothesis that bladder cancer could be detected noninvasively by a simple and reliable assay targeting genomic ...
Rajendra B Nerli +5 more
doaj +1 more source
Molecules, 2017 Many synthetic peptides have been developed for diagnosis and therapy of human cancers based on their ability to target specific receptors on cancer cell surface or to penetrate the cell membrane.
Anna Lucia Tornesello +3 more
doaj +1 more source
Drug Repositioning For Allosteric Modulation of VIP and PACAP Receptors
Frontiers in Endocrinology, 2021 Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are two neuropeptides that contribute to the regulation of intestinal motility and secretion, exocrine and endocrine secretions, and homeostasis of the ...
Ingrid Langer, Dorota Latek
doaj +1 more source
Vasoactive intestinal peptide receptors in the airways of smokers with chronic bronchitis [PDF]
European Respiratory Journal, 2004 Vasoactive intestinal peptide (VIP) is a neuropeptide involved in the regulation of airway mucus secretion. The biological functions of VIP are mediated through two receptors, the vasoactive intestinal peptide receptor type 1 (VPAC1R) and type 2 (VPAC2R).
MIOTTO, Deborah +6 more
openaire +3 more sources
Frontiers in Pharmacology, 2016 Pituitary adenylate cyclase-activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) through the binding of vasoactive intestinal peptide receptors (VIPRs), perform a wide variety of effects in human cancers, including glioblastoma ...
Grazia eMaugeri +7 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2020 Vasoactive intestinal peptide (VIP) is an important modulatory peptide throughout the CNS acting as a neurotransmitter, neurotrophic or neuroprotective factor.
Diana Cunha-Reis +3 more
doaj +1 more source
Targeting VIP and PACAP Receptor Signalling: New Therapeutic Strategies in Multiple Sclerosis
ASN Neuro, 2011 MS (multiple sclerosis) is a chronic autoimmune and neurodegenerative pathology of the CNS (central nervous system) affecting approx. 2.5 million people worldwide. Current and emerging DMDs (disease-modifying drugs) predominantly target the immune system.
Yossan-Var Tan, James A Waschek
doaj +1 more source
Journal of Biological Chemistry, 1987 The biological effects of vasoactive intestinal peptide (VIP) are mediated by binding to a membrane-bound receptor. Probes designed to trap this receptor by binding to it in a covalent way may suffer from a greatly reduced affinity. We report here, for the VIP receptor, the use of a photoaffinity probe obtained by derivatization of receptor-bound VIP ...
A, Robichon, P F, Kuks, J, Besson
openaire +2 more sources
Acute exercise inhibits gastric emptying of liquids in rats: influence of the NO-cGMP pathway
Brazilian Journal of Medical and Biological Research, 2018 We previously found that acute exercise inhibited the gastric emptying of liquid in awake rats by causing an acid-base imbalance. In the present study, we investigated the involvement of the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway ...
A.K.M. Cavalcante +5 more
doaj +1 more source
Animal Research and One Health, EarlyView.Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar +8 more
wiley +1 more source