Results 31 to 40 of about 15,888 (236)
Neuroimmune communication in allergic rhinitis
Frontiers in Neurology, 2023 The prevalence rate of allergic rhinitis (AR) is high worldwide. The inhalation of allergens induces AR, which is an immunoglobulin E-mediated and type 2 inflammation-driven disease.
Yi Zhou +7 more
doaj +1 more source
Characterization of vasoactive intestinal peptide receptors on human megakaryocytes and platelets [PDF]
Blood, 1996 Vasoactive intestinal peptide receptor I (VIPRI) expression was examined in megakaryocytes using reverse transcriptase-polymerase chain reaction (RT-PCR). VIPRI protein was characterized in platelet membranes using covalent crosslinking techniques.
S K, Park +4 more
openaire +2 more sources
Neuropeptide Receptors: Novel Targets for HIV/AIDS Therapeutics
Pharmaceuticals, 2011 The vasoactive intestinal peptide/pituitary adenylyl cyclase-activating polypepetide (VPAC) receptors are important for many physiologic functions, including glucose homeostasis, neuroprotection, memory, gut function, modulation of the immune system and ...
Donald R. Branch
doaj +1 more source
Tracing the Origins of the Pituitary Adenylate-Cyclase Activating Polypeptide (PACAP)
Frontiers in Neuroscience, 2020 Pituitary adenylate cyclase activating polypeptide (PACAP) is a well-conserved neuropeptide characteristic of vertebrates. This pluripotent hypothalamic neuropeptide regulates neurotransmitter release, intestinal motility, metabolism, cell division ...
João C. R. Cardoso +2 more
doaj +1 more source
The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach [PDF]
, 2013 The calcitonin gene-related peptide (CGRP) receptor is a complex of a calcitonin receptor-like receptor (CLR), which is a family B G-protein-coupled receptor (GPCR) and receptor activity modifying protein 1.
Poyner, David +18 more
core +1 more source
Detection of bladder cancer using voided urine sample and by targeting genomic VPAC receptors
Indian Journal of Urology, 2021 Introduction: Cells exfoliated into urine from the bladder can help to diagnose the cancer. The objective of this study was to validate the hypothesis that bladder cancer could be detected noninvasively by a simple and reliable assay targeting genomic ...
Rajendra B Nerli +5 more
doaj +1 more source
Molecules, 2017 Many synthetic peptides have been developed for diagnosis and therapy of human cancers based on their ability to target specific receptors on cancer cell surface or to penetrate the cell membrane.
Anna Lucia Tornesello +3 more
doaj +1 more source
Journal of Biological Chemistry, 1987 The biological effects of vasoactive intestinal peptide (VIP) are mediated by binding to a membrane-bound receptor. Probes designed to trap this receptor by binding to it in a covalent way may suffer from a greatly reduced affinity. We report here, for the VIP receptor, the use of a photoaffinity probe obtained by derivatization of receptor-bound VIP ...
A, Robichon, P F, Kuks, J, Besson
openaire +2 more sources
Endothelins. Myocardial actions of a new class of cytokines [PDF]
, 1992 There is growing evidence to support the existence of a dynamic interaction in vivo between cardiac myocytes and adjacent microvascular endothelial cells in the regulation of both cardiac myocyte and possibly endothelial cell phenotype and function ...
Smith, T. W. +3 more
core +1 more source
Frontiers in Cellular Neuroscience, 2020 Vasoactive intestinal peptide (VIP) is an important modulatory peptide throughout the CNS acting as a neurotransmitter, neurotrophic or neuroprotective factor.
Diana Cunha-Reis +3 more
doaj +1 more source