Vasoactive Intestinal Peptide Regulates its Receptor Expression and Functions of Human Keratinocytes via Type I Vasoactive Intestinal Peptide Receptors [PDF]
Vasoactive intestinal peptide has been suggested to play some roles in inflammatory dermatoses such as atopic dermatitis and psoriasis. The aim of this study is to clarify the precise mechanisms of how vasoactive intestinal peptide is implicated in the pathogenesis of these disorders.
Kakurai, Maki +5 more
openaire +2 more sources
Glycyrrhizic Acid Reduces Heart Rate and Blood Pressure by a Dual Mechanism
Beta adrenergic receptors are crucial for their role in rhythmic contraction of heart along with their role in the pathological conditions such as tachycardia and high risk of heart failure.
Kailash Singh +6 more
doaj +1 more source
G Protein-Coupled Receptors as Potential Intercellular Communication Mediators in Trypanosomatidae
Detection and transduction of environmental signals, constitute a prerequisite for successful parasite invasion; i.e., Leishmania transmission, survival, pathogenesis and disease manifestation and dissemination, with diverse molecules functioning as ...
Emilia Díaz +7 more
doaj +1 more source
Vasoactive intestinal peptide (VIP), a gut peptide hormone originally reported as a vasodilator in 1970, has multiple physiological and pathological effects on development, growth, and the control of neuronal, epithelial, and endocrine cell functions ...
Mari Iwasaki +2 more
doaj +1 more source
Presence of Vasoactive Intestinal Peptide Receptor in the Hen Hypothalamus.
Radioligand assays of the membrane fraction of hen hypothalamic tissues involving the preoptic (HPOA) or median eminence (HMEA) areas revealed the presence of a specific binding component to chicken vasoactive intestinal peptide (cVIP) having properties of a receptor. The equilibrium dissociation constant (Kd) was 0.70 +/- 0.07 nM (Mean +/- SEM; N = 5)
GONZALES, SYLVIA MAST +4 more
openaire +3 more sources
Neuropeptide G Protein-Coupled Receptors as Oncotargets
Neuropeptide G protein-coupled receptors (GPCRs) are overexpressed on numerous cancer cells. In a number of tumors, such as small cell lung cancer (SCLC), bombesin (BB) like peptides and neurotensin (NTS) function as autocrine growth factors whereby they
Terry W. Moody +2 more
doaj +1 more source
Neuroimmune communication in allergic rhinitis
The prevalence rate of allergic rhinitis (AR) is high worldwide. The inhalation of allergens induces AR, which is an immunoglobulin E-mediated and type 2 inflammation-driven disease.
Yi Zhou +7 more
doaj +1 more source
Neuropeptide Receptors: Novel Targets for HIV/AIDS Therapeutics
The vasoactive intestinal peptide/pituitary adenylyl cyclase-activating polypepetide (VPAC) receptors are important for many physiologic functions, including glucose homeostasis, neuroprotection, memory, gut function, modulation of the immune system and ...
Donald R. Branch
doaj +1 more source
Tracing the Origins of the Pituitary Adenylate-Cyclase Activating Polypeptide (PACAP)
Pituitary adenylate cyclase activating polypeptide (PACAP) is a well-conserved neuropeptide characteristic of vertebrates. This pluripotent hypothalamic neuropeptide regulates neurotransmitter release, intestinal motility, metabolism, cell division ...
João C. R. Cardoso +2 more
doaj +1 more source
Characterization of vasoactive intestinal peptide receptors on human megakaryocytes and platelets [PDF]
Vasoactive intestinal peptide receptor I (VIPRI) expression was examined in megakaryocytes using reverse transcriptase-polymerase chain reaction (RT-PCR). VIPRI protein was characterized in platelet membranes using covalent crosslinking techniques.
S K, Park +4 more
openaire +2 more sources

