Results 191 to 200 of about 2,349,142 (333)

Enhancing melatonin biosynthesis in crops through synthetic genetic circuits: A strategy for nutritional fortification in soybean and stress resistance in cotton

Plant Biotechnology Journal, EarlyView.
Summary Melatonin has gained considerable prominence in the treatment of insomnia that significantly impacts one‐third of the global population. The production of melatonin remains challenging due to limitations in current methods. Thus, there is an urgent need for developing more efficient and innovative production techniques.
Yue Shi, Zegang Han, Wanying Zhang, Lu He, Zhuolin Shi, Xiaowei Ma, Ji Zhou, Zhanfeng Si, Yan Hu, Tianzhen Zhang   +9 more
wiley   +1 more source

Insights Into the Pathophysiology of Catecholamine-Refractory Shock: A Narrative Review. [PDF]

Cureus
Gonçalves A, Gonçalves Pereira F, Fernandes S, Gonçalves Pereira J.   +3 more
europepmc   +1 more source

Oxytocin‐induced contractions within rat and rabbit ejaculatory tissues are mediated by vasopressin V1A receptors and not oxytocin receptors

British Journal of Pharmacology, 2008
J. Gupta, R. Russell, C. Wayman, D. Hurley, V. Jackson   +4 more
semanticscholar   +1 more source

Impact of public health and patient‐centered prevention strategies on periodontitis and caries as causes of tooth loss in high‐income countries

Periodontology 2000, EarlyView.
Abstract In high‐income countries, the oral health of the population is influenced by public health interventions, widespread use of oral care products, dental practice measures, and the cost of dental treatment. We compiled information on changes of the prevalence of proximal and upstream determinants of periodontitis, caries, and tooth loss over the ...
Thomas Kocher, Peter Meisel, Sebastian Baumeister, Birte Holtfreter   +3 more
wiley   +1 more source

Cell Type-Specific Expression of Purinergic P2X Receptors in the Hypothalamus. [PDF]

Int J Mol Sci
Cihakova J, Ivetic M, Zemkova H.
europepmc   +1 more source

Engineered surface strategies to manage dental implant‐related infections

Periodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza, Bruna E. Nagay, Rodrigo Martins, Martinna Bertolini, Jamil A. Shibli, Conrado Aparicio, Magda Feres, Valentim A. R. Barão   +7 more
wiley   +1 more source

The psychedelic-peptide paradox: a hormetic hypothesis. [PDF]

Compr Psychoneuroendocrinol
Carter CS.
europepmc   +1 more source

The role of orexin A in the pathogenesis of ischaemic stroke at high altitude

Experimental Physiology, EarlyView.
Schematic illustration of the experimental design. This study investigated the role of Orexin A in the pathogenesis of ischemic stroke at high altitude. Abstract Orexin offers protection against cerebral ischaemia–reperfusion injury, with high altitude playing a key role in modulating its expression.
Minxia Zhu, Xu Guo, Jing Guo, Zhaojun Zhang, Kexin Zhang, Yaqi Lei, Yuhe Wang, Haoshuang Zhan   +7 more
wiley   +1 more source

Effect of experimental hypoosmolar hyponatremia on the blood brain barrier and brain edema formation. [PDF]

Sci Rep
Aleksandrowicz M, Wencel P, Kciuk M, Popek M, Przykaza Ł.   +4 more
europepmc   +1 more source

Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications

Experimental Physiology, EarlyView.
Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó, Luis Eduardo M. Quintas   +1 more
wiley   +1 more source