Results 11 to 20 of about 370,363 (269)

Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application

Haematologica, 2008
Background Donor lymphocyte infusion is an effective form of adoptive immunotherapy for hematologic malignancies after allogeneic stem cell transplantation.
Marieke Griffioen, H.M. Esther van Egmond, Helen Barnby-Porritt, Menno A.W.G. van der Hoorn, Renate S. Hagedoorn, Michel G.D. Kester, Nikolai Schwabe, Roel Willemze, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk   +9 more
doaj   +1 more source

Host Cellular Receptors for the Peste des Petits Ruminant Virus

Viruses, 2019
Peste des Petits Ruminant (PPR) is an important transboundary, OIE-listed contagious viral disease of primarily sheep and goats caused by the PPR virus (PPRV), which belongs to the genus Morbillivirus of the family Paramyxoviridae.
Meera Prajapati, Niyokwishimira Alfred, Yongxi Dou, Xiangping Yin, Raju Prajapati, Yanmin Li, Zhidong Zhang   +6 more
doaj   +1 more source

Virus sensing receptors in cellular infectivity of influenza A virus

Journal of Infection in Developing Countries, 2021
An innate immune response is essential to mobilize protective immunity upon the infection of respiratory epithelial cells with influenza A virus (IAV).
Shaihana Almatrrouk, Iram Saba, Suhair Abozaid, Ahmed A Al-Qahtani, Mohammed N Al-Ahdal   +4 more
doaj   +1 more source

Phosphatidylserine treatment relieves the block to retrovirus infection of cells expressing glycosylated virus receptors

Retrovirology, 2005
Background A major determinant of retrovirus host range is the presence or absence of appropriate cell-surface receptors required for virus entry. Often orthologs of functional receptors are present in a wide range of species, but amino acid differences ...
Coil David A, Miller A Dusty
doaj   +1 more source

Cytokine production and signaling pathways in respiratory virus infection

Frontiers in Microbiology, 2013
It has been confirmed that respiratory virus infections can induce abberant cytokine production in the host. These cytokines may be associated with both elimination of the virus and complications in the host, such as virus-induced asthma.
Hirokazu eKimura, Masakazu eYoshizumi, Haruyuki eIshii, Kazunori eOishi, Akihide eRyo   +4 more
doaj   +1 more source

Murine Polyomavirus Cell Surface Receptors Activate Distinct Signaling Pathways Required for Infection

mBio, 2016
Virus binding to the cell surface triggers an array of host responses, including activation of specific signaling pathways that facilitate steps in virus entry.
Samantha D. O’Hara, Robert L. Garcea
doaj   +1 more source

Influenza A Virus Hemagglutinin–Neuraminidase–Receptor Balance: Preserving Virus Motility [PDF]

Trends in Microbiology, 2020
Influenza A viruses (IAVs) occasionally cross the species barrier and adapt to novel host species. This requires readjustment of the functional balance of the sialic acid receptor-binding hemagglutinin (HA) and the receptor-destroying neuraminidase (NA) to the sialoglycan-receptor repertoire of the new host.
de Vries, Erik, Du, Wenjuan, Guo, Hongbo, de Haan, Cornelis A M   +3 more
openaire   +4 more sources

The Roles of Coinhibitory Receptors in Pathogenesis of Human Retroviral Infections

Frontiers in Immunology, 2018
Costimulatory and coinhibitory receptors play a key role in regulating immune responses to infection and cancer. Coinhibitory receptors include programmed cell death 1 (PD-1), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), and T cell ...
Keiko Yasuma-Mitobe, Masao Matsuoka, Masao Matsuoka   +2 more
doaj   +1 more source

Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections. [PDF]

PLoS Pathogens, 2012
A subset of human papillomavirus (HPV) infections is causally related to the development of human epithelial tumors and cancers. Like a number of pathogens, HPV entry into target cells is initiated by first binding to heparan sulfonated proteoglycan ...
Zurab Surviladze, Agnieszka Dziduszko, Michelle A Ozbun   +2 more
doaj   +1 more source

Comparative distribution of human and avian type sialic acid influenza receptors in the pig

BMC Veterinary Research, 2010
Background A major determinant of influenza infection is the presence of virus receptors on susceptible host cells to which the viral haemagglutinin is able to bind.
Perez Belinda, White Gavin A, Kuchipudi Suresh V, Nelli Rahul K, Dunham Stephen P, Chang Kin-Chow   +5 more
doaj   +1 more source