Results 11 to 20 of about 4,110,019 (315)
Influenza–Host Interplay and Strategies for Universal Vaccine Development
Vaccines, 2020 Influenza is an annual epidemic and an occasional pandemic caused by pathogens that are responsible for infectious respiratory disease. Humans are highly susceptible to the infection mediated by influenza A viruses (IAV).
Hye Suk Hwang +2 more
doaj +1 more source
A multitask transfer learning framework for the prediction of virus-human protein-protein interactions [PDF]
BMC Bioinformatics 2021, 2021 Viral infections are causing significant morbidity and mortality worldwide. Understanding the interaction patterns between a particular virus and human proteins plays a crucial role in unveiling the underlying mechanism of viral infection and pathogenesis. This could further help in the prevention and treatment of virus-related diseases.
arxiv +1 more source
Numerical simulation of the viral entry into a cell driven by receptor diffusion [PDF]
, 2021 The present study focuses on the receptor driven endocytosis typical of viral entry into a cell. A locally increased density of receptors at the time of contact between the cell and the virus is necessary in this case. The virus is considered as a substrate with fixed receptors on its surface, whereas the receptors of the host cell are free to move ...
arxiv +1 more source
Direct visualization of superselective colloid-surface binding mediated by multivalent interactions [PDF]
, 2021 Reliably distinguishing between cells based on minute differences in receptor density is crucial for cell-cell or virus-cell recognition, the initiation of signal transduction and selective targeting in directed drug delivery. Such sharp differentiation between different surfaces based on their receptor density can only be achieved by multivalent ...
arxiv +1 more source
RIG-I-like receptors: their regulation and roles in RNA sensing
Nature reviews. Immunology, 2020 Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are key sensors of virus infection, mediating the transcriptional induction of type I interferons and other genes that collectively establish an antiviral host response.
J. Rehwinkel, Michaela U. Gack
semanticscholar +1 more source
Tropism and Infectivity of Pandemic Influenza A H1N1/09 Virus in the Human Placenta
Viruses, 2022 Influenza virus infection in pregnant women may put the fetus at higher risk; however, to date, there has been no detailed research about the expression of influenza virus receptors in the human placenta.
Yan-Na Xiao +3 more
doaj +1 more source
Influenza Virus Infections in Polarized Cells
Viruses, 2022 In humans and other mammals, the respiratory tract is represented by a complex network of polarized epithelial cells, forming an apical surface facing the external environment and a basal surface attached to the basement layer.
Beatriz Praena, Xiu-Feng Wan
doaj +1 more source
Identification of a receptor for an extinct virus [PDF]
Proceedings of the National Academy of Sciences, 2010 The resurrection of endogenous retroviruses from inactive molecular fossils has allowed the investigation of interactions between extinct pathogens and their hosts that occurred millions of years ago. Two such paleoviruses, chimpanzee endogenous retrovirus-1 and -2 (CERV1 and CERV2), are relatives of modern MLVs and are found in the ...
Soll, Steven J. +2 more
openaire +4 more sources
Archives of immunology and allergy, 2018 Silver ions from dissolved silver nitrate; Silver nitrate (AgNO3): AgNO3→Ag + + NO3 Silver nanoparticles (AgNPs): Ag0 + (oxidant)→ Ag++ (oxidant)-, and Ag+ + Lx→ AgL(x-1), L is ligand.
Dr. Sci. Tsuneo Ishida
semanticscholar +1 more source
The role of IgG Fc receptors in antibody-dependent enhancement
Nature reviews. Immunology, 2020 Antibody-dependent enhancement (ADE) is a mechanism by which the pathogenesis of certain viral infections is enhanced in the presence of sub-neutralizing or cross-reactive non-neutralizing antiviral antibodies.
S. Bournazos, Aaron Gupta, J. Ravetch
semanticscholar +1 more source