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The SARS-CoV-2 Spike Protein is vulnerable to moderate electric fields [PDF]
, 2021 Most of the ongoing projects aimed at the development of specific therapies and vaccines against COVID-19 use the SARS-CoV-2 spike (S) protein as the main target [1-3]. The binding of the spike protein with the ACE2 receptor (ACE2) of the host cell constitutes the first and key step for virus entry. During this process, the receptor binding domain (RBD)
arxiv +1 more source
Journal of NeuroVirology, 2005 There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind rabies virus and/or facilitate rabies virus entry into cells.
openaire +4 more sources
Tropical Medicine and Health, 2011 Dengue virus is an arthropod-borne virus transmitted by Aedes mosquitoes. Dengue virus causes fever and hemorrhagic disorders in humans and non-human primates. Direct interaction of the virus introduced by a mosquito bite with host receptor molecule(s) is crucial for virus propagation and the pathological progression of dengue diseases.
Takashi Suzuki, Kazuya I.P.J. Hidari
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Cell surface receptors, virus entry and tropism of primate lentiviruses.
Journal of General Virology, 2002 Human immunodeficiency virus (HIV) exploits cell surface receptors to attach to and gain entry into cells. The HIV envelope spike glycoprotein on the surface of virus particles binds both CD4 and a seven-transmembrane coreceptor.
P. Clapham, Á. McKnight
semanticscholar +1 more source
Haematologica, 2008 Background Donor lymphocyte infusion is an effective form of adoptive immunotherapy for hematologic malignancies after allogeneic stem cell transplantation.
Marieke Griffioen +9 more
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Bad vibrations: Quantum tunnelling in the context of SARS-CoV-2 infection [PDF]
Sci Rep 12, 16929 (2022), 2021 The SARS-CoV-2 pandemic has added new urgency to the study of viral mechanisms of infection. But while vaccines offer a measure of protection against this specific outbreak, a new era of pandemics has been predicted. In addition to this, COVID-19 has drawn attention to post-viral syndromes and the healthcare burden they entail.
arxiv +1 more source
EVIHVR: A platform for analysis of expression, variation and identification of human virus receptors
Infectious Medicine, 2022 Motivation: Virus receptors are presented on the cell surfaces of a host and are key for viral infection of host cells. However, no unified resource for the study of viral receptors is currently available.
Zheng Zhang +4 more
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Host Cellular Receptors for the Peste des Petits Ruminant Virus
Viruses, 2019 Peste des Petits Ruminant (PPR) is an important transboundary, OIE-listed contagious viral disease of primarily sheep and goats caused by the PPR virus (PPRV), which belongs to the genus Morbillivirus of the family Paramyxoviridae.
Meera Prajapati +6 more
doaj +1 more source
Viruses, 2016 The hemagglutinin (H) protein of measles virus (MeV) interacts with a cellular receptor which constitutes the initial stage of infection. Binding of H to this host cell receptor subsequently triggers the F protein to activate fusion between virus and ...
Liang-Tzung Lin, C. Richardson
semanticscholar +1 more source
Retrovirology, 2005 Background A major determinant of retrovirus host range is the presence or absence of appropriate cell-surface receptors required for virus entry. Often orthologs of functional receptors are present in a wide range of species, but amino acid differences ...
Coil David A, Miller A Dusty
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