A Systemic Receptor Network Triggered by Human cytomegalovirus Entry [PDF]
, 2010 Virus entry is a multistep process that triggers a variety of cellular pathways interconnecting into a complex network, yet the molecular complexity of this network remains largely unsolved.
Li, Hong, Ren, Li, Wang, Anyou
core +4 more sources
Insights into neutralization of animal viruses gained from study of influenza virus [PDF]
, 1991 It has long been known that the binding of antibodies to viruses can result in a loss of infectivity, or neutralization, but little is understood of the mechanism or mechanisms of this process.
Colonno +17 more
core +2 more sources
Cytokine production and signaling pathways in respiratory virus infection
Frontiers in Microbiology, 2013 It has been confirmed that respiratory virus infections can induce abberant cytokine production in the host. These cytokines may be associated with both elimination of the virus and complications in the host, such as virus-induced asthma.
Hirokazu eKimura +4 more
doaj +1 more source
Antiviral treatment alters the frequency of activating and inhibitory receptor-expressing natural killer cells in chronic Hepatitis B virus infected patients [PDF]
, 2012 Natural killer (NK) cells play a critical role in innate antiviral immunity, but little is known about the impact of antiviral therapy on the frequency of NK cell subsets.
Chi, X. +12 more
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mBio, 2016 Virus binding to the cell surface triggers an array of host responses, including activation of specific signaling pathways that facilitate steps in virus entry.
Samantha D. O’Hara, Robert L. Garcea
doaj +1 more source
Mathematical Model of HIV superinfection dynamics and R5 to X4 switch [PDF]
, 2006 During the HIV infection several quasispecies of the virus arise, which are able to use different coreceptors, in particular the CCR5 and CXCR4 coreceptors (R5 and X4 phenotypes, respectively).
Bagnoli, Franco +2 more
core +1 more source
Oligosaccharides as Receptors for JC Virus [PDF]
Journal of Virology, 2002 ABSTRACT JC virus (JCV) belongs to the polyomavirus family of double-stranded DNA viruses and in humans causes a demyelinating disease of the central nervous system, progressive multifocal leukoencephalopathy. Its hemagglutination activity and entry into host cells have been reported to depend on an N-linked glycoprotein containing sialic ...
Rika, Komagome +6 more
openaire +2 more sources
The Roles of Coinhibitory Receptors in Pathogenesis of Human Retroviral Infections
Frontiers in Immunology, 2018 Costimulatory and coinhibitory receptors play a key role in regulating immune responses to infection and cancer. Coinhibitory receptors include programmed cell death 1 (PD-1), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), and T cell ...
Keiko Yasuma-Mitobe +2 more
doaj +1 more source
Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections. [PDF]
PLoS Pathogens, 2012 A subset of human papillomavirus (HPV) infections is causally related to the development of human epithelial tumors and cancers. Like a number of pathogens, HPV entry into target cells is initiated by first binding to heparan sulfonated proteoglycan ...
Zurab Surviladze +2 more
doaj +1 more source
Comparative distribution of human and avian type sialic acid influenza receptors in the pig
BMC Veterinary Research, 2010 Background A major determinant of influenza infection is the presence of virus receptors on susceptible host cells to which the viral haemagglutinin is able to bind.
Perez Belinda +5 more
doaj +1 more source