Results 31 to 40 of about 4,142,916 (290)
mBio, 2016 Virus binding to the cell surface triggers an array of host responses, including activation of specific signaling pathways that facilitate steps in virus entry.
Samantha D. O’Hara, Robert L. Garcea
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The Roles of Coinhibitory Receptors in Pathogenesis of Human Retroviral Infections
Frontiers in Immunology, 2018 Costimulatory and coinhibitory receptors play a key role in regulating immune responses to infection and cancer. Coinhibitory receptors include programmed cell death 1 (PD-1), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), and T cell ...
Keiko Yasuma-Mitobe +2 more
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Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections. [PDF]
PLoS Pathogens, 2012 A subset of human papillomavirus (HPV) infections is causally related to the development of human epithelial tumors and cancers. Like a number of pathogens, HPV entry into target cells is initiated by first binding to heparan sulfonated proteoglycan ...
Zurab Surviladze +2 more
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Structural basis for human coronavirus attachment to sialic acid receptors
Nature Structural & Molecular Biology, 2019 Coronaviruses cause respiratory tract infections in humans and outbreaks of deadly pneumonia worldwide. Infections are initiated by the transmembrane spike (S) glycoprotein, which binds to host receptors and fuses the viral and cellular membranes.
M. A. Tortorici +10 more
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Comparative distribution of human and avian type sialic acid influenza receptors in the pig
BMC Veterinary Research, 2010 Background A major determinant of influenza infection is the presence of virus receptors on susceptible host cells to which the viral haemagglutinin is able to bind.
Perez Belinda +5 more
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Viruses, 2018 Wild birds are the reservoir for low-pathogenic avian influenza viruses, which are frequently transmitted to domestic birds and occasionally to mammals. In 2014, an H10N7 virus caused severe mortality in harbor seals in northeastern Europe.
Anne Dittrich +6 more
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BiomoleculesViruses are obligate intracellular parasites that rely on cell surface receptor molecules to complete the first step of invading host cells. The experimental method for virus receptor screening is time-consuming, and receptor molecules have been ...
Yang Sun +8 more
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High affinity allele for the gene of FCGR3A is risk factor for HIV infection and progression. [PDF]
PLoS ONE, 2010 We investigated the genetics of Fc receptors, which function as activating receptors on immune cells and help to control HIV through antibody-mediated cellular cytotoxicity.
Bhawna Poonia +2 more
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Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors
Nature Communications, 2014 Mammals express the sialic acids N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) on cell surfaces, where they act as receptors for pathogens, including influenza A virus (IAV).
Preston S K Ng +14 more
semanticscholar +1 more source
Receptors for Hepatitis C Virus
Journal of Virology, 2000 The nature of the receptors enabling hepatitis C virus (HCV) entry into cells has been the subject of debate. On one hand, ligand panning with recombinant HCV envelope protein has identified CD81, a member of the tetraspanin superfamily of proteins, as a direct ligand for the E2 glycoprotein (7) but fails to explain virus tropism.
Ian M. Jones +3 more
openaire +4 more sources