Results 31 to 40 of about 599,966 (310)

Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections. [PDF]

open access: yesPLoS Pathogens, 2012
A subset of human papillomavirus (HPV) infections is causally related to the development of human epithelial tumors and cancers. Like a number of pathogens, HPV entry into target cells is initiated by first binding to heparan sulfonated proteoglycan ...
Zurab Surviladze   +2 more
doaj   +1 more source

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein [PDF]

open access: yes, 2014
Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) protein ...
Bert Schepens   +20 more
core   +3 more sources

Comparative distribution of human and avian type sialic acid influenza receptors in the pig

open access: yesBMC Veterinary Research, 2010
Background A major determinant of influenza infection is the presence of virus receptors on susceptible host cells to which the viral haemagglutinin is able to bind.
Perez Belinda   +5 more
doaj   +1 more source

Envelope-receptor interactions in Nipah virus pathobiology. [PDF]

open access: yes, 2007
Nipah (NiV) and Hendra (HeV) viruses are members of the newly defined Henipavirus genus of the Paramyxoviridae. Nipah virus (NiV) is an emergent paramyxovirus that causes fatal encephalitis in up to 70% of infected patients, and there is increasing ...
Lee, Benhur
core   +1 more source

Impact of Mutations in the Hemagglutinin of H10N7 Viruses Isolated from Seals on Virus Replication in Avian and Human Cells

open access: yesViruses, 2018
Wild birds are the reservoir for low-pathogenic avian influenza viruses, which are frequently transmitted to domestic birds and occasionally to mammals. In 2014, an H10N7 virus caused severe mortality in harbor seals in northeastern Europe.
Anne Dittrich   +6 more
doaj   +1 more source

GateView: A Multi-Omics Platform for Gene Feature Analysis of Virus Receptors within Human Normal Tissues and Tumors

open access: yesBiomolecules
Viruses are obligate intracellular parasites that rely on cell surface receptor molecules to complete the first step of invading host cells. The experimental method for virus receptor screening is time-consuming, and receptor molecules have been ...
Yang Sun   +8 more
doaj   +1 more source

High affinity allele for the gene of FCGR3A is risk factor for HIV infection and progression. [PDF]

open access: yesPLoS ONE, 2010
We investigated the genetics of Fc receptors, which function as activating receptors on immune cells and help to control HIV through antibody-mediated cellular cytotoxicity.
Bhawna Poonia   +2 more
doaj   +1 more source

Receptors for Hepatitis C Virus

open access: yesJournal of Virology, 2000
The nature of the receptors enabling hepatitis C virus (HCV) entry into cells has been the subject of debate. On one hand, ligand panning with recombinant HCV envelope protein has identified CD81, a member of the tetraspanin superfamily of proteins, as a direct ligand for the E2 glycoprotein (7) but fails to explain virus tropism.
Ian M. Jones   +3 more
openaire   +4 more sources

Specificity switching in virus–receptor complexes [PDF]

open access: yesCurrent Opinion in Structural Biology, 2009
Several structures of complexes between viral attachment proteins and their cellular receptors have been determined recently, enhancing our understanding of the molecular recognition processes that guide formation of virus-receptor complexes. Moreover, these structures also highlight strategies by which highly similar viral proteins within a single ...
Thilo Stehle   +2 more
openaire   +3 more sources

TAM Receptors Are Not Required for Zika Virus Infection in Mice

open access: yesCell Reports, 2017
Summary: Tyro3, Axl, and Mertk (TAM) receptors are candidate entry receptors for infection with the Zika virus (ZIKV), an emerging flavivirus of global public health concern.
Andrew K. Hastings   +12 more
doaj   +1 more source

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