Results 31 to 40 of about 4,117,687 (315)
A Systemic Receptor Network Triggered by Human cytomegalovirus Entry [PDF]
Virus entry is a multistep process that triggers a variety of cellular pathways interconnecting into a complex network, yet the molecular complexity of this network remains largely unsolved. Here, by employing systems biology approach, we reveal a systemic virus-entry network initiated by human cytomegalovirus (HCMV), a widespread opportunistic ...
arxiv +1 more source
Receptors and routes of dengue virus entry into the host cells.
Dengue is the most prevalent arthropod-borne viral disease, caused by dengue virus, a member of the Flaviviridae family. Its worldwide incidence is now a major health problem, with 2.5 billion people living in risk areas. In this review, we integrate the
Christine Cruz-Oliveira+5 more
semanticscholar +1 more source
Molecular mechanisms behind anti SARS-CoV-2 action of lactoferrin [PDF]
Despite the huge effort to contain the infection, the novel SARS-CoV-2 coronavirus has rapidly become pandemics, mainly due to its extremely high human-to-human transmission capability, and a surprisingly high viral charge of symptom-less people. While the seek of a vaccine is still ongoing, promising results have been obtained with antiviral compounds.
arxiv +1 more source
Oligosaccharides as Receptors for JC Virus [PDF]
ABSTRACT JC virus (JCV) belongs to the polyomavirus family of double-stranded DNA viruses and in humans causes a demyelinating disease of the central nervous system, progressive multifocal leukoencephalopathy. Its hemagglutination activity and entry into host cells have been reported to depend on an N-linked glycoprotein containing sialic ...
Shinya Tanaka+6 more
openaire +3 more sources
Rabies causes approximately 60,000 casualties annually and has a case fatality rate approaching 100% once clinical signs occur. The glycoprotein on the surface of the virion is important for the host immune response and facilitates interaction of the ...
Marianne Lian+2 more
doaj
Virus recognition of glycan receptors
Attachment of viruses to cell-surface receptors is the initial step in infection. Many mammalian viruses have evolved to recognize receptors that are glycans on cell-surface glycoproteins or glycolipids. Although glycans are a ubiquitous component of mammalian cells, the types of terminal structures expressed vary among different cell-types and tissues,
Andrew J Thompson+2 more
openaire +4 more sources
Cytokine production and signaling pathways in respiratory virus infection
It has been confirmed that respiratory virus infections can induce abberant cytokine production in the host. These cytokines may be associated with both elimination of the virus and complications in the host, such as virus-induced asthma.
Hirokazu eKimura+4 more
doaj +1 more source
Virus sensing receptors in cellular infectivity of influenza A virus
An innate immune response is essential to mobilize protective immunity upon the infection of respiratory epithelial cells with influenza A virus (IAV). The response is classified as early (nonspecific effectors), local systematic (effector cells recruitment) and late (antigen to lymphoid organ transport, naive B and T cells recognition, effector cells ...
Shaihana Almatrrouk+4 more
openaire +3 more sources
Virus binding to the cell surface triggers an array of host responses, including activation of specific signaling pathways that facilitate steps in virus entry.
Samantha D. O’Hara, Robert L. Garcea
doaj +1 more source
Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections. [PDF]
A subset of human papillomavirus (HPV) infections is causally related to the development of human epithelial tumors and cancers. Like a number of pathogens, HPV entry into target cells is initiated by first binding to heparan sulfonated proteoglycan ...
Zurab Surviladze+2 more
doaj +1 more source