Envelope-receptor interactions in Nipah virus pathobiology. [PDF]
Nipah (NiV) and Hendra (HeV) viruses are members of the newly defined Henipavirus genus of the Paramyxoviridae. Nipah virus (NiV) is an emergent paramyxovirus that causes fatal encephalitis in up to 70% of infected patients, and there is increasing ...
Lee, Benhur
core +1 more source
The Roles of Coinhibitory Receptors in Pathogenesis of Human Retroviral Infections
Costimulatory and coinhibitory receptors play a key role in regulating immune responses to infection and cancer. Coinhibitory receptors include programmed cell death 1 (PD-1), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), and T cell ...
Keiko Yasuma-Mitobe+2 more
doaj +1 more source
Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections. [PDF]
A subset of human papillomavirus (HPV) infections is causally related to the development of human epithelial tumors and cancers. Like a number of pathogens, HPV entry into target cells is initiated by first binding to heparan sulfonated proteoglycan ...
Zurab Surviladze+2 more
doaj +1 more source
Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein [PDF]
Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) protein ...
Bert Schepens+20 more
core +3 more sources
Structural basis for human coronavirus attachment to sialic acid receptors
Coronaviruses cause respiratory tract infections in humans and outbreaks of deadly pneumonia worldwide. Infections are initiated by the transmembrane spike (S) glycoprotein, which binds to host receptors and fuses the viral and cellular membranes.
M. A. Tortorici+10 more
semanticscholar +1 more source
Comparative distribution of human and avian type sialic acid influenza receptors in the pig
Background A major determinant of influenza infection is the presence of virus receptors on susceptible host cells to which the viral haemagglutinin is able to bind.
Perez Belinda+5 more
doaj +1 more source
Wild birds are the reservoir for low-pathogenic avian influenza viruses, which are frequently transmitted to domestic birds and occasionally to mammals. In 2014, an H10N7 virus caused severe mortality in harbor seals in northeastern Europe.
Anne Dittrich+6 more
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Loss-of-function analysis of EphA receptors in retinotectal mapping [PDF]
Peer reviewedPublisher ...
DeChiara, Thomas M.+7 more
core +1 more source
Viruses are obligate intracellular parasites that rely on cell surface receptor molecules to complete the first step of invading host cells. The experimental method for virus receptor screening is time-consuming, and receptor molecules have been ...
Yang Sun+8 more
doaj +1 more source
High affinity allele for the gene of FCGR3A is risk factor for HIV infection and progression. [PDF]
We investigated the genetics of Fc receptors, which function as activating receptors on immune cells and help to control HIV through antibody-mediated cellular cytotoxicity.
Bhawna Poonia+2 more
doaj +1 more source