Results 81 to 90 of about 599,966 (310)

Measles Virus Receptor SLAM (CD150)

open access: yesVirology, 2002
Measles virus (MV), a member of the Morbillivirus genus in the Paramyxoviridae family, is an enveloped virus with a nonsegmented negative-strand RNA genome and infects humans and nonhuman primates (Griffin, 2001). Despite the availability of vaccines, MV remains a major cause of childhood mortality, claiming roughly one million lives a year worldwide ...
Koji Hashimoto   +4 more
openaire   +3 more sources

TurboID-mediated proximity labeling technologies to identify virus co-receptors

open access: yesFrontiers in Cellular and Infection Microbiology
Virus receptors determine the tissue tropism of viruses and have a certain relationship with the clinical outcomes caused by viral infection, which is of great importance for the identification of virus receptors to understand the infection mechanism of ...
Bo Wang   +5 more
doaj   +1 more source

Technology and Biological Weapons: Future Threats [PDF]

open access: yes, 2004
Ye
Davison, N., Millett, P., Nixdorff, K.
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Host factors and early treatments to restrict paediatric HIV infection and early disease progression [PDF]

open access: yes, 2015
open6noA body of evidence indicates that a threshold level of the virus is required to establish systemic and persistent HIV infection in the host and that this level depends on virus-host interactions.
De Rossi, Anita   +5 more
core   +1 more source

Neutralizing Antibody-Resistant Hepatitis C Virus Cell-to-Cell Transmission [PDF]

open access: yes, 2010
Hepatitis C virus (HCV) can initiate infection by cell-free particle and cell-cell contact-dependent transmission. In this study we use a novel infectious coculture system to examine these alternative modes of infection.
Balfe, Peter   +12 more
core   +4 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Virus-Receptor Interaction in an Adenovirus System [PDF]

open access: yesJournal of Virology, 1968
HeLa or KB cells each contain around 10 4 receptor sites for adenovirus type 2. These are inactivated by treatment of live cells with subtilisin. The receptor activity of the enzyme-treated cells is regained after 4 to 8 hr of incubation in complete medium. A technique that utilizes the difference in buoyant density
Lennart Philipson   +2 more
openaire   +3 more sources

Sialic Acid Receptor Specificity in Mammary Gland of Dairy Cattle Infected with Highly Pathogenic Avian Influenza A(H5N1) Virus

open access: yesEmerging Infectious Diseases
In March 2024, the US Department of Agriculture’s Animal and Plant Health Inspection Service reported detection of highly pathogenic avian influenza (HPAI) A(H5N1) virus in dairy cattle in the United States for the first time. One factor that determines
Rahul K. Nelli   +13 more
doaj   +1 more source

The Natural Selection of Herpesviruses and Virus-Specific NK Cell Receptors

open access: yesViruses, 2009
During the co-evolution of cytomegalovirus (CMV) and natural killer (NK) cells, each has evolved specific tactics in an attempt to prevail. CMV has evolved multiple immune evasion mechanisms to avoid detection by NK cells and other immune cells, leading ...
Joseph C. Sun, Lewis L. Lanier
doaj   +1 more source

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