Results 81 to 90 of about 235,128 (161)
Virus encoded cytokines and cytokine receptors
Parasitology, 1997 In order to replicate efficiently within the host, viruses have evolved multiple strategies to evade the host's immune system. In many cases viruses have actually hijacked various components of the host's immune system to ensure their own survival. One such strategy is the expression of virus encoded cytokines and cytokine receptors. Members of
M, Barry, G, McFadden
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Chemokine expression and viral infection of the central nervous system: regulation of host defense and neuropathology. [PDF]
, 2001 An effective host response against viral infection of the central nervous system (CNS) is the principal factor dictating the outcome of infection. It is the responsibility of the immune response to contain and control viral replication. Paradoxically, it
Lane, TE, Liu, MT
core
Using Cystine Knot Proteins as a Novel Approach to Retarget Oncolytic Measles Virus. [PDF]
, 2017 Modified measles virus (MV) has effective oncolytic activity preclinically and is currently being investigated in clinical trials for various types of cancer. We investigated the use of cystine knot proteins (CKPs) to direct MV activity.
Lal, Sangeet, Raffel, Corey
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Virus entry: old viruses, new receptors
Current Opinion in Virology, 2012 The long-sought entry receptors for rubella, sindbis and respiratory syncytial viruses (RV, SV and RSV), together with the missing measles virus (MV) receptor for infection of epithelial cells, were identified in 2011. These have been major developments in the field of virus entry. In addition, 2011 was rich in new information about the interactions of
Backovic, Marija, Rey, Felix A
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Hepatitis C Virus Evasion from RIG-I-Dependent Hepatic Innate Immunity
Gastroenterology Research and Practice, 2010 Exposure to hepatitis C virus (HCV) usually results in persistent infection that often develops into chronic liver disease. Interferon-alpha (IFN) treatment comprises the foundation of current approved therapy for chronic HCV infection but is limited in ...
Helene Minyi Liu, Michael Gale
doaj +1 more source
Soluble levels of receptor for advanced glycation endproducts and dysfunctional high-density lipoprotein in persons infected with human immunodeficiency virus: ACTG NWCS332. [PDF]
, 2018 The role of high-density lipoprotein (HDL) function and advanced glycation end products (AGEs) in HIV-related atherosclerotic cardiovascular disease (CVD) is unclear.
Aberg, Judith A +5 more
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Pathogens, 2013 Acute respiratory tract infection (RTI) is a leading cause of morbidity and mortality worldwide and the majority of RTIs are caused by viruses, among which respiratory syncytial virus (RSV) and the closely related human metapneumovirus (hMPV) figure ...
Thangam Sudha Velayutham +2 more
doaj +1 more source
Vaccinia protein C16 blocks innate immune sensing of DNA by binding the Ku complex [PDF]
, 2011 VACV gene C16L encodes a 37-kDa protein that is highly conserved in orthopoxviruses and functions as an immunomodulator. Intranasal infection of mice with a virus lacking C16L (vΔC16) induced less weight loss, fewer signs of illness and increased ...
Peters, Nicholas Edward +1 more
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Pattern recognition receptors and their roles in antiviral innate immunity in livestock
Frontiers in ImmunologyViral infectious diseases pose a persistent challenge to global livestock production, animal welfare, and food security, emphasizing the critical role of early host defense mechanisms in limiting viral replication and transmission.
Shujing Liu +8 more
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Virus-Receptor Interactions: Structural Insights For Oncolytic Virus Development.
Oncolytic virotherapy, 2019 Recent advancements in oncolytic virotherapy commend a special attention to developing new strategies for targeting cancer cells with oncolytic viruses (OVs). Modifications of the viral envelope or coat proteins serve as a logical mean of repurposing viruses for cancer treatment.
Jayawardena, Nadishka +3 more
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