Results 31 to 40 of about 5,994,707 (387)
Live-Cell Imaging of Single Receptor Composition Using Zero-Mode Waveguide Nanostructures [PDF]
, 2012 We exploit the optical and spatial features of subwavelength nanostructures to examine individual receptors on the plasma membrane of living cells. Receptors were sequestered in portions of the membrane projected into zero-mode waveguides.
Dougherty, Dennis A. +6 more
core +1 more source
Receptor-Based Strategies for Overcoming Resistance in Cancer Therapy
ReceptorsThis review article explores the fundamental role of receptor targeting in overcoming drug resistance in cancer therapy, an area of critical concern given the persistently high rates of cancer morbidity and mortality globally.
Naresh Sah +7 more
doaj +1 more source
Current strategies in engaging oncolytic viruses with antitumor immunity
Molecular Therapy: Oncolytics, 2021 Oncolytic virotherapy has produced promising yet limited results in preclinical and clinical studies. Besides direct oncolytic activity, a significant therapeutic mechanism of oncolytic virotherapy is the induction of tumor-specific immunity ...
Drew Ashton Boagni +2 more
doaj +1 more source
The evolution and comparative neurobiology of endocannabinoid signalling [PDF]
, 2012 CB(1)- and CB(2)-type cannabinoid receptors mediate effects of the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide in mammals. In canonical endocannabinoid-mediated synaptic plasticity, 2-AG is generated postsynaptically by diacylglycerol ...
Devane W. A. +4 more
core +1 more source
Stabilin Receptors: Role as Phosphatidylserine Receptors [PDF]
Biomolecules, 2019 Phosphatidylserine is a membrane phospholipid that is localized to the inner leaflet of the plasma membrane. Phosphatidylserine externalization to the outer leaflet of the plasma membrane is an important signal for various physiological processes, including apoptosis, platelet activation, cell fusion, lymphocyte activation, and regenerative axonal ...
Seung-Yoon Park, In-San Kim
openaire +4 more sources
ReceptorsFolate receptor alpha (FRα) is a glycosylphosphatidylinositol (GPI) membrane-anchored protein containing three N-glycosylated residues at the N47, N139, and N179 termini.
Emilyn B. Aucoin +9 more
doaj +1 more source
Complex evolutionary dynamics of massively expanded chemosensory receptor families in an extreme generalist chelicerate herbivore [PDF]
, 2016 While mechanisms to detoxify plant produced, anti-herbivore compounds have been associated with plant host use by herbivores, less is known about the role of chemosensory perception in their life histories.
Bajda-Wybouw, Sabina +10 more
core +4 more sources
European Journal of Medical Research, 2010 Leptin or obesity receptor (Ob-R) is a member of class I cytokine receptor family. Ob-R, expressed in six isoforms, is the product of alternative RNA splicing of db gene. According to its structural differences, the receptor's isoforms are divided into three classes: long, short, and secretory isoforms.
Anna Stelmaszczyk-Emmel +5 more
openaire +3 more sources
Molecular Perspectives on Prostate Cancer: The Role of microRNAs in Androgen Receptor Regulation
ReceptorsProstate cancer (PCa) is the most prevalent cancer among men globally. In addition to environmental risk factors, genetic factors play a crucial role in its development and progression, highlighting the regulation of key genes as an essential aspect. The
Asbiel Felipe Garibaldi-Ríos +6 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 Hearing relies on the transduction of sound-evoked vibrations into electrical signals, occurring in the stereocilia bundle of inner ear hair cells. The G protein-coupled receptor (GPCR) ADGRV1 and the multi-PDZ protein PDZD7 play a critical role in the ...
Baptiste Colcombet-Cazenave +11 more
doaj +1 more source