Results 71 to 80 of about 2,221,739 (262)

RNase P-Associated External Guide Sequences Inhibit HIV-1 Infection by Shutting Down Human CCR5 Expression

Receptors
Background: External guide sequences (EGSs) are small RNA molecules capable of hybridizing to a target mRNA and rendering the target RNA susceptible to degradation by ribonuclease P (RNase P), a tRNA processing enzyme.
Yujun Liu, Bin Yan, Isadora Zhang, Fenyong Liu   +3 more
doaj   +1 more source

Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo [PDF]

, 2009
Background Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter which mainly mediates its effects on neurons via ionotropic (GABAA) and metabotropic (GABAB) receptors.
Brugger, Stefan, Stefan Brugger, Martina Kurejova, Tegeder Imgard, Gangadharan Vijayan, Imgard Tegeder, Gangadharan, Vijayan, Tegeder, Irmgard, Kuner Rohini, Kurejova, Martina, Rohini Kuner, Kurejova Martina, Nitin Agarwal, Bernhard Bettler, Brugger Stefan, Vijayan Gangadharan, Tegeder, Imgard, Agarwal, Nitin, Bettler Bernhard, Bettler, Bernhard, Agarwal Nitin, Kuner, Rohini   +21 more
core   +1 more source

Chemokine Receptors and Phagocyte Biology in Zebrafish. [PDF]

, 2020
Phagocytes are highly motile immune cells that ingest and clear microbial invaders, harmful substances, and dying cells. Their function is critically dependent on the expression of chemokine receptors, a class of G-protein-coupled receptors (GPCRs ...
Sommer, F., Torraca, Vincenzo, Sommer, Frida, Meijer, Annemarie H, Meijer, Annemarie H., Torraca, V., Meijer, A.H.   +6 more
core   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko, Segev Gabay, Jonathan Roth, Amit Ringel, Rina Dvir, Shlomi Constantini   +5 more
wiley   +1 more source

Role of Glucocorticoid Receptor in Triple-Negative Breast Cancer

Receptors
Triple-negative breast cancer (TNBC) is an aggressive tumor among breast cancer subtypes with much lower overall survival at metastasis compared to other subtypes and with limited treatment options due to a lack of targeted therapies. This has led to the
Raj Kumar
doaj   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

The Prorenin Receptor: Multitasking Its Way Through Cardiovascular, Metabolic and Renal Diseases

Receptors
The renin–angiotensin–aldosterone system (RAAS) is a fundamental regulator of blood pressure, electrolyte balance, fluid homeostasis, and tissue remodeling.
Andrea S. Marrero-Bras, Sarah E. Thomas, Joshua D. Parquet, Zoe Vallotton, Bolu Adewale, Brianna Crabtree, Minolfa C. Prieto   +6 more
doaj   +1 more source

The sushi domains and their role in GABA(B) receptor compartmentalization [PDF]

, 2010
GABAB receptors are G protein-coupled receptors ...
Biermann, Barbara
core   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Recent Advances in the Exploitation of Cell Surface Receptors for Targeted Cell Therapies

Receptors
The past decade has witnessed significant expansion in both preclinical and approved receptor-targeted therapeutic cell modalities. These include immune cells engineered to express chimeric antigen receptors (CARs), and bispecific immune cell engagers ...
Ronard Kwizera, Ananda Kumar Kanduluru, Madduri Srinivasarao   +2 more
doaj   +1 more source