Results 41 to 50 of about 46,431 (264)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Yiqi Huoxue recipe ameliorates diabetic nephropathy by mediating VAPB–PTPIP51 complex to activate autophagy and regulate MAM contact

Frontiers in Nutrition
BackgroundDiabetic nephropathy (DN), a major complication of diabetes mellitus (DM), poses a high mortality and a global health burden. Mitochondria-associated endoplasmic reticulum membranes (MAMs) and mediated autophagy are regarded as the crucial ...
Linghao Dai, Mengyi Wang, Bo Wang, Haowei Liang, Yang Guan, Zhongyan Du, Hui Wang, Hui Wang, Hui Wang   +8 more
doaj   +1 more source

Étude et analyses des dégradations du manuscrit de Nizet

CeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2014
The Nizet manuscript of the 18th century covers the genealogy of four families of Verviers : the Nizet, Graffard, Hacraÿ and Laurentÿ families. The book is damaged and presents black stained areas in the paper which are transfers of gold-like and silver ...
Cecilia Duminuco
doaj   +1 more source

The development of new technologies of obtaining ice cream from almond milk

Алматы технологиялық университетінің хабаршысы, 2021
The article discusses the technology of obtaining ice cream from almond milk, which is useful for people with diabetes and who have lactose intolerance.
N. S. Mashanova, M. E. Smagulova, S. T. Azimova, J. I. Sataeva   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

DEVELOPMENT AND RESEARCH OF A FUNCTIONAL DRINK WITH THE ADDITION OF PEPPERMINT EXTRACT

Современная наука и инновации, 2023
The modern food market is regularly replenished with new functional food products. When selling food products, it is important to consider that the larger the range of tastes on offer, the better for their implementation.
G. Ag. Hamatgaleeva
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Popular vegetarian diets in China: a sustainable dietary option for the globe?

Frontiers in Sustainable Food Systems
Vegetarian practices have historically been ingrained in Chinese society. However, it is uncertain to what extent these practices correspond to the global concept of a sustainable diet.
Yaxian Zhang, Wenpeng Du, Wenpeng Du, Xiaozhi Xiang, Xiaozhi Xiang, Manxiang Ji, Xiaqing Wang   +6 more
doaj   +1 more source