Results 51 to 60 of about 104,977 (303)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Recreating a Historical Recipe: Blanch Creame

open access: yes, 2020
The moment I got this assignment I knew I wanted to reconstruct a historical recipe: I love cooking so historical reconstruction is a particular interest of mine.
tallulahmaait
core  

Awangardowa książka kucharska?

open access: yesMiędzy Oryginałem a Przekładem, 2020
Avant-garde Cookbook? The Polish Translation of The Alice B. Toklas Cookbook The article focuses on the Polish translation of The Alice B. Toklas Cookbook. The author provides examples which prove that Toklas’s book may be read as a functional text as
Karolina Kwaśna
doaj   +1 more source

Syrups in Sugar Confectionery Products of High Nutritional Value [PDF]

open access: yesТехника и технология пищевых производств, 2019
Confectionery products of high nutritional value are affordable and rich in vitamins and minerals. Their development requires new raw materials with a high physiological value, which would be available on the local consumer market.
Reznichenko I.   +3 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Revisiting the Fried Chicken Recipe [PDF]

open access: yes, 2022
Twenty-five years ago, Gary Lawson introduced us to legal theory’s tastiest analogy. He told us about a late-eighteenth-century recipe for making fried chicken and how we ought to interpret it. Lawson’s pithy essay has much to be praised.
Pohlman, Zachary B.
core   +1 more source

Recipe Book Memories

open access: yes, 2017
By Abbie Burnett  The digital recipe book project has opened our minds to recognise that recipe books can include more than just recipes for meals, some posts on this blog explore this topic in more detail (Faye's post and Sarah's post).
Abbie Burnett
core   +1 more source

Étude et analyses des dégradations du manuscrit de Nizet

open access: yesCeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2014
The Nizet manuscript of the 18th century covers the genealogy of four families of Verviers : the Nizet, Graffard, Hacraÿ and Laurentÿ families. The book is damaged and presents black stained areas in the paper which are transfers of gold-like and silver ...
Cecilia Duminuco
doaj   +1 more source

A Recipe for Success

open access: yesImmunology & Cell Biology
AbstractIn this article, I aim to give some pieces of career advise for young immunologists based on my own experiences.
openaire   +2 more sources

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

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