Results 51 to 60 of about 46,431 (264)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

FROM A MONOMODAL RECIPE TO A MULTIMODAL OFFER. A TEXTOLOGICAL AND MEDIOLINGUISTIC APPROACH

Humanities and Social Sciences, 2018
Not so long ago recipes were included in 'obvious' text types functioning „unproblematically in the sphere of everyday life”[1], because their relatively uncomplicated structure did not cause any difficulties with recognition and qualification, or with ...
Anna HANUS, Dorota KACZMAREK
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Development of technology and recipe of sweet buns enriched with food additives

Новые технологии, 2018
The article presents data on the effect of the method of application of "Tomato Powder" and "Topinambur Powder" food additives on technological modes of production and quality of sweet bakery products.
M. A. Kazimirova, T. V. Pershakova, A. N. Matvienko, T. A. Shakhray, O. V. Fedoseeva   +4 more
doaj  

A Recipe for Success

Immunology & Cell Biology
AbstractIn this article, I aim to give some pieces of career advise for young immunologists based on my own experiences.
openaire   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Use of dandelion root in functional bread technology

Новые технологии
Prevention of nutritional diseases with the help of functional foods remains relevant. Therefore, the development of food technology using raw materials that contribute to the formation of functional properties is relevant and has scientific and ...
A. P. Korolev, O. V. Feofilaktova, N. V. Zavorokhina, A. V. Tarasov   +3 more
doaj   +1 more source

Zoysia Soil-Less Green Roof’s Performance: A Life Cycle Assessment

Environmental and Climate Technologies, 2022
The use of green roofs is demonstrated to improve the energy performance of buildings, increase biodiversity, reduce environmental impacts of urban areas, and mitigate climate change phenomena. Their use on a large scale is desirable in the coming years.
Muscas Desirée, Frota De Albuquerque Landi Fabiana, Fabiani Claudia, Grohmann David, Rocchi Lucia   +4 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source