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Elegant and Innovative Recoding Strategies for Advancing Vaccine Development [PDF]
VaccinesRecoding strategies have emerged as a promising approach for developing safer and more effective vaccines by altering the genetic structure of microorganisms, such as viruses, without changing their proteins.
François Meurens +2 more
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C to U RNA editing of MFN1 is regulated by ADARB1 and associates with favourable prognosis in chronic lymphocytic leukemia [PDF]
Scientific ReportsCytidine to uridine (C-to-U) as well as adenosine to inosine (A-to-I) RNA editing denotes the posttranscriptional modification of RNA by specialized RNA deaminases.
Alejandra Gonzalez Martinez +14 more
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Seeing the unseen in characterizing RNA editome during rice endosperm development [PDF]
Communications BiologyRice (Oryza sativa L.) endosperm is essential to provide nutrients for seed germination and determine grain yield. RNA editing, a post-transcriptional modification essential for plant development, unfortunately, is not fully characterized during rice ...
Ming Chen +12 more
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Investigating the impact of synonymous gene recoding on a recombinantly expressed monoclonal antibody under different process parameters [PDF]
Bioengineering & Translational MedicineMonoclonal antibodies (mAbs) are commonly used biologic therapeutics with a wide variety of clinical applications. During the development process, manufacturers consider different production parameters to improve protein yield and achieve appropriate ...
Nayiri M. Kaissarian +7 more
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Revista Farol, 2020 When Varèse lived in that street sixty years earlier, he was creating Poème Electronique, a commission from the Philips company. The eight-minutes song would become the soundtrack of the pavilion created by Le Corbusier at the 1958 Brussels World's Fair.
Bruno Moreschi, Gabriel Pereira
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PLoS Pathogens, 2023 Virus genome recoding is an attenuation method that confers genetically stable attenuation by rewriting a virus genome with numerous silent mutations. Prior flavivirus genome recoding attempts utilised codon deoptimisation approaches.
Wei-Xin Chin +15 more
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Nucleic Acids Research, 2003 The RECODE database is a compilation of translational recoding events (programmed ribosomal frameshifting, codon redefinition and translational bypass). The database provides information about the genes utilizing these events for their expression, recoding sites, stimulatory sequences and other relevant information.
Pavel V, Baranov +4 more
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Molecular Microbiology, 2004 SummaryStandard decoding of the genetic information into polypeptides is performed by one of the most sophisticated cell machineries, the translating ribosome, which, by following the genetic code, ensures the correspondence between the mature mRNA and the protein sequence.
CobucciPonzano B, Rossi M, Moracci M
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Urban Shivers: Recoding Actual Space in Disco Elysium
Галактика медиа: журнал медиа исследований, 2022 The functioning of urban space in games is often passive, since the city acts as an object of observation, a scenery for the player’s actions. In the Disco Elysium game, the city receives its voice, soul, and will, which the player can observe by ...
Arina R. Medvedeva
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Genomic markers on synthetic genomes
Engineering in Life Sciences, 2021 Genome synthesis endows scientists the ability of de novo creating genomes absent in nature, by thorough redesigning DNA sequences and introducing numerous custom features. However, the genome synthesis is a labor‐ and time‐consuming work, and thus it is
Hao‐Qian Zhao +3 more
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