Results 11 to 20 of about 532,969 (259)

Production of functional recombinant antibodies in Dictyostelium discoideum [PDF]

open access: yesBMC Research Notes
Objective Recombinant antibodies are essential reagents for diagnostics, research, and therapy. Numerous production methods have been developed, each of them with its strengths and weaknesses.
Cyril Guilhen, Tania Jauslin
doaj   +2 more sources

Recombinant Antibody Technology [PDF]

open access: yesILAR Journal, 1995
36:801-803. Smith, D.B., and K.S. Johnson. 1988. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 67:31-40. Snapper, CM., and J.J. Mond. 1993. Towards a comprehensive view of immunoglobulin class switching. Immunol. Today 14:15-17. Snorasse, T., B. Flamand, G. De Becker, H. Bazin, F.
Alexander E., Karn   +2 more
openaire   +2 more sources

Recombinant Antibodies for Academia: A Practical Approach

open access: yesCHIMIA, 2016
After several decades of optimization, phage display technology enables the routine isolation and production of recombinant monoclonal antibodies in vitro.
Pierre Cosson, Oliver Hartley
doaj   +1 more source

Recombinant Measles AIK-C Vaccine Strain Expressing the prM-E Antigen of Japanese Encephalitis Virus. [PDF]

open access: yesPLoS ONE, 2016
An inactivated Japanese encephalitis virus (JEV) vaccine, which induces neutralizing antibodies, has been used for many years in Japan. In the present study, the JEV prM-E protein gene was cloned, inserted at the P/M junction of measles AIK-C cDNA, and ...
Akira Higuchi   +3 more
doaj   +1 more source

The international, prospective Glanzmann Thrombasthenia Registry: treatment and outcomes in surgical intervention

open access: yesHaematologica, 2015
Standard treatment for Glanzmann thrombasthenia, a severe inherited bleeding disorder, is platelet transfusion. Recombinant factor VIIa is reported to be effective in Glanzmann thrombasthenia with platelet antibodies and/or refractoriness to platelet ...
Man-Chiu Poon   +5 more
doaj   +1 more source

Generation of hapten-specific recombinant antibodies: antibody phage display technology: a review

open access: yesVeterinární Medicína, 2005
Production of antibodies has been revolutionized by the development of modern molecular biology methods for the expression of recombinant DNA. Phage display technology represents one of the most powerful tools for production and selection of recombinant ...
J. Brichta, M. Hnilova, T. Viskovic
doaj   +1 more source

Expression of the recombinant C-terminal of the S1 domain and N-terminal of the S2 domain of the spike protein of porcine epidemic diarrhea virus [PDF]

open access: yesVeterinary World, 2021
Background and Aim: Porcine epidemic diarrhea virus (PEDV) causes severe diarrhea in suckling piglets, leading to severe economic losses in the swine industry.
Jiraporn Sritun   +7 more
doaj   +1 more source

A Humoral Immune Response Alters the Distribution of Enzyme Replacement Therapy in Murine Mucopolysaccharidosis Type I

open access: yesMolecular Therapy: Methods & Clinical Development, 2018
Antibodies against recombinant proteins can significantly reduce their effectiveness in unanticipated ways. We evaluated the humoral response of mice with the lysosomal storage disease mucopolysaccharidosis type I treated with weekly intravenous ...
Steven Q. Le   +11 more
doaj   +1 more source

A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice

open access: yesToxins, 2023
Equine-derived antitoxin (BAT®) is the only treatment for botulism from botulinum neurotoxin serotype G (BoNT/G). BAT® is a foreign protein with potentially severe adverse effects and is not renewable.
Yongfeng Fan   +9 more
doaj   +1 more source

Recombinant antibodies and their use in biosensors [PDF]

open access: yesAnalytical and Bioanalytical Chemistry, 2011
Inexpensive, noninvasive immunoassays can be used to quickly detect disease in humans. Immunoassay sensitivity and specificity are decidedly dependent upon high-affinity, antigen-specific antibodies. Antibodies are produced biologically. As such, antibody quality and suitability for use in immunoassays cannot be readily determined or controlled by ...
Xiangqun, Zeng   +2 more
openaire   +2 more sources

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