Strategies and Considerations for Improving Recombinant Antibody Production and Quality in Chinese Hamster Ovary Cells [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Recombinant antibodies are rapidly developing therapeutic agents; approximately 40 novel antibody molecules enter clinical trials each year, most of which are produced from Chinese hamster ovary (CHO) cells.
Jun-He Zhang +6 more
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Development of Recombinant Antibody by Yeast Surface Display Technology [PDF]
Current Research in Pharmacology and Drug DiscoveryRecombinant antibodies have emerged as powerful tools in various fields, including therapeutics, diagnostics, and research applications. The selection of high-affinity antibodies with desired specificity is a crucial step in the development of ...
Mujahed I. Mustafa +2 more
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Recombinant Antibody Vaccines for Targeted Antigen Delivery: Design Principles and Immunological Applications [PDF]
VaccinesVaccines that elicit durable immune responses require efficient delivery of antigen to antigen-presenting cells (APCs), in combination with appropriate contextual signals that promote immunity.
Kaitlyn M. Pirogovsky, Daniel Hawiger
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Rapid-format recombinant antibody-based methods for the diagnosis of Clostridioides difficile infection: Recent advances and perspectives [PDF]
Frontiers in Microbiology, 2022 Clostridioides difficile, the most common cause of nosocomial diarrhea, has been continuously reported as a worldwide problem in healthcare settings. Additionally, the emergence of hypervirulent strains of C.
Hamideh Raeisi +4 more
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Novel single-chain antibodies against highly conserved epitopes in the hemagglutinin of influenza A viruses: Promising agents for universal therapies [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Development of new antibodies with broad activity would provide anti-influenza prophylaxis and treatment. Human single-chain variable fragments (scFvs) are considered effective agents against viruses.
Samaneh Alizadeh +4 more
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Communications Biology, 2021 Kelil, Gallo et al. develop an antibody discovery strategy, termed CellectSeq, for targeting integral membrane proteins on native cells. This strategy uses motif-based scoring and sequencing error-filtering algorithms to identify antibodies with high ...
Abdellali Kelil +4 more
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Journal of the Indonesian Tropical Animal Agriculture, 2023 This research was aimed to analyze antibody response in laying hens post vaccinated by Newcastle Disease Virus (NDV) recombinat Fusion (F) protein which has been succesfully expressed from the F gene of local isolates of NDV from Kulon Progo strain (0663/
J. Jawad +3 more
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Research Progress in Affinity Enhancement Strategies for Recombinant Antibodies against Food Hazards [PDF]
Shipin Kexue, 2023 As a new generation of genetically engineered antibodies, recombinant antibodies are widely used in immunodetection of food hazards due to their simple structure as well as easy expression and modification.
WANG Feng, XIE Xi, MA Lukai, WANG Qin, XIAO Gengsheng, SHEN Yudong, XU Zhenlin, WANG Hong
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A strong case for third-party testing
eLife, 2023 A strategy to identify high-quality commercially available antibodies for research reveals extensive use of non-specific antibodies and offers solutions for future large-scale testing.
Fridtjof Lund-Johansen
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Antibody Reports, 2022 The recombinant human antibody clone P5G6 (AX353) in an engineered scFv-Fc format detects by immunofluorescence cell-surface proteins on cryosections of monkey esophagus.
Christoph M. Hammers, Jens Wrammert
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