Results 61 to 70 of about 532,969 (259)
Evaluation of Indigenous Latex Agglutination Assay based on Recombinant Pasteurella Lipoprotein E (rPlpE) As Antigen for Detection of Anti Mannheimia Haemolytica - IgG Antibodies [PDF]
Archives of Razi InstituteMannheimia haemolytica (M. haemolytica) is an organism causing pneumonia in ruminants. M. haemolytica leads to severe economic losses to the global livestock industry.
Nafiseh karimi +3 more
doaj +1 more source
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
A multi-Fc-species system for recombinant antibody production
BMC Biotechnology, 2009 Background Genomic, transcriptomic and proteomic projects often suffer from a lack of functional validation creating a strong demand for specific and versatile antibodies.
Nizak Clément +6 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro +25 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj +23 more
wiley +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Phage Display’s Prospects for Early Diagnosis of Prostate Cancer
VirusesProstate cancer (PC) is the second most diagnosed cancer among men. It was observed that early diagnosis of disease is highly beneficial for the survival of cancer patients.
Valery A. Petrenko
doaj +1 more source
Portable Molecularly Imprinted Polymer Sensor for Rapid Swab‐Based Detection of Norovirus
Advanced Healthcare Materials, EarlyView.This work reports a rapid, portable smartphone‐based sensor capable of detecting four norovirus genotypes from swab samples within 15 min. Sensor selectivity was validated through evaluation against four common live viruses. The swab‐based sampling process enabled simple sample preparation combined with the compact detection system, supporting use of ...
Amy Dann +13 more
wiley +1 more source
Human antibodies neutralizing the alpha-latrotoxin of the European black widow
Frontiers in ImmunologyPoisoning by widow-spider (genus Latrodectus) bites occurs worldwide. The illness, termed latrodectism, can cause severe and persistent pain and can lead to muscle rigidity, respiratory complications, and cardiac problems. It is a global health challenge
Maximilian Ruschig +12 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett +7 more
wiley +1 more source