Trends in Peptide and Protein Sciences, 2019 Insulin-Like Growth Factor-1 (IGF-1) is a small peptide with 70 amino acids and 7.6 kDa molecular weight that acts as the major mediator of growth hormone. According to the previous studies, recombinant production of human IGF-1 (rhIGF-1) in E.
Sara Hemmati, Javad Ranjbari
doaj +1 more source
A recombinant single chain antibody interleukin-2 fusion protein [PDF]
British Journal of Cancer, 1993 Recombinant interleukin-2 (rIL-2) therapy has been shown to be of value in the treatment of some cases of melanoma and renal cell carcinoma. However, its use can be limited by severe systemic toxicity. Targeting rIL-2 to the tumor should improve the antitumor immune response and decrease the systemic toxicity.
P, Savage +3 more
openaire +3 more sources
BMC Biotechnology, 2009 Background Expression of recombinant proteins in green algal chloroplast holds substantial promise as a platform for the production of human therapeutic proteins.
Henry Ryan E +2 more
doaj +1 more source
Absolute Protein Amounts and Relative Abundance of Volume-regulated Anion Channel (VRAC) LRRC8 Subunits in Cells and Tissues Revealed by Quantitative Immunoblotting [PDF]
, 2019 The volume-regulated anion channel (VRAC) plays an important role in osmotic cell volume regulation. In addition, it is involved in various physiological processes such as insulin secretion, glia-neuron communication and purinergic signaling.
Kopp, Anja +3 more
core +1 more source
Production of Recombinant Echinococcus granulosus Antigen B Subunits, In Order to Using Of Them in Serodiagnostic Tests of Hydatidosis [PDF]
Iranian Journal of Public Health, 2007 Background: Hydatidosis is one of the most important helminthiasis, and is a public health problem in many regions of the world. Methods: With the aim of production of recombinant subunits of antigen B, two different sequences of Echinococcus granulosus
R Pazoki +4 more
doaj +1 more source
Russell-like bodies in plant seeds share common features with prolamin bodies and occur upon recombinant protein production [PDF]
, 2019 Although many recombinant proteins have been produced in seeds at high yields without adverse effects on the plant, endoplasmic reticulum (ER) stress and aberrant localization of endogenous or recombinant proteins have also been reported.
Arcalis, Elsa +13 more
core +2 more sources
HaloTag is an effective expression and solubilisation fusion partner for a range of fibroblast growth factors [PDF]
PeerJ, 2015 The production of recombinant proteins such as the fibroblast growth factors (FGFs) is the key to establishing their function in cell communication. The production of recombinant FGFs in E.
Changye Sun +5 more
doaj +2 more sources
Simplified ELISA for Detecting Antibodies to Recombinant Fusion Proteins
BioTechniques, 1997 Sergio Carmona +2 more
doaj +3 more sources
Deglycosylation of proteins for crystallization using recombinant fusion protein glycosidases [PDF]
Protein Science, 1996 AbstractObtaining high quality protein crystals remains a rate‐limiting step in the determination of three‐dimensional X‐ray structures. A frequently encountered problem in this respect is the high or heterogeneous carbohydrate content of many eukaryotic proteins.
F, Grueninger-Leitch +3 more
openaire +2 more sources
Recombinant human preproinsulin expression, purification and reaction with insulin autoantibodies in sera from patients with insulin-dependent diabetes mellitus [PDF]
, 1993 A novel prokaryotic expression vector pGEX-6T was designed for high-level expression of recombinant fusion protein with a histidine-hexapeptide and glutathione-S-transferase at its N-terminus and the recombinant human preproinsulin at its C-terminus ...
Amman +29 more
core +1 more source