Results 21 to 30 of about 391,068 (308)

Deglycosylation of proteins for crystallization using recombinant fusion protein glycosidases [PDF]

Protein Science, 1996
AbstractObtaining high quality protein crystals remains a rate‐limiting step in the determination of three‐dimensional X‐ray structures. A frequently encountered problem in this respect is the high or heterogeneous carbohydrate content of many eukaryotic proteins.
F, Grueninger-Leitch, A, D'Arcy, B, D'Arcy, C, Chène   +3 more
openaire   +2 more sources

Co-expression with the Type 3 Secretion Chaperone CesT from Enterohemorrhagic E. coli Increases Accumulation of Recombinant Tir in Plant Chloroplasts

Frontiers in Plant Science, 2017
Type 3 secretion systems (T3SSs) are utilized by pathogenic Escherichia coli to infect their hosts and many proteins from these systems are affected by chaperones specific to T3SS-containing bacteria.
Jacqueline MacDonald, Sean Miletic, Sean Miletic, Typhanie Gaildry, Typhanie Gaildry, Adam Chin-Fatt, Adam Chin-Fatt, Rima Menassa   +7 more
doaj   +1 more source

Molecular cloning and expression of novel fibroblast growth factor-2 conjugated with immunodominant domains of pseudomonas exotoxin [PDF]

, 2015
Angiogenesis is very important in cancer growth and metastasis. Basic fibroblast growth factor (bFGF) as one of the most important angiogenesis factors is an attractive target for cancer vaccine.
Farazmandfar, T., Haghighatfard, H., Hakemi, M.G., Jadidi-Niaragh, F., Samaei, N.M., Yamchi, A., Yazdani, Y.   +6 more
core   +1 more source

Expression of Tumor Necrosis Factor-Related Apoptosis- Inducing Ligand Conjugated to the scFV Region of Anti-CD20 Antibody Using a Small Ubiquitin-related Modifier [PDF]

مجله علمی دانشگاه علوم پزشکی کردستان, 2023
Background and Aim: Conventional treatments have shown little success in cancer treatment. Using antibody fragments conjugated with specific proteins and targeting specific receptors is a new strategy for producing anticancer drugs.
mahsa rasekhian, MARYAM pourjalili, omid tavallaei   +2 more
doaj  

Production of the biocommodities butanol and acetone from methanol with fluorescent FAST-tagged proteins using metabolically engineered strains of Eubacterium limosum

Biotechnology for Biofuels, 2021
Background The interest in using methanol as a substrate to cultivate acetogens increased in recent years since it can be sustainably produced from syngas and has the additional benefit of reducing greenhouse gas emissions.
Maximilian Flaiz, Gideon Ludwig, Frank R. Bengelsdorf, Peter Dürre   +3 more
doaj   +1 more source

Human and bovine respiratory syncytial virus vaccine research and development [PDF]

, 2008
Human (HRSV) and bovine (BRSV) respiratory syncytial viruses (RSV) are two closely related viruses, which are the most important causative agents of respiratory tract infections of young children and calves, respectively.
Deplanche, Martine, Meyer, Gilles, Schelcher, François   +2 more
core   +2 more sources

Inhibition of the Hantavirus Fusion Process by Predicted Domain III and Stem Peptides from Glycoprotein Gc. [PDF]

PLoS Neglected Tropical Diseases, 2016
Hantaviruses can cause hantavirus pulmonary syndrome or hemorrhagic fever with renal syndrome in humans. To enter cells, hantaviruses fuse their envelope membrane with host cell membranes.
Gonzalo P Barriga, Fernando Villalón-Letelier, Chantal L Márquez, Eduardo A Bignon, Rodrigo Acuña, Breyan H Ross, Octavio Monasterio, Gonzalo A Mardones, Simon E Vidal, Nicole D Tischler   +9 more
doaj   +1 more source

Complexity of the Ruminococcus flavefaciens FD-1 cellulosome reflects an expansion of family-related protein-protein interactions [PDF]

, 2017
This work was supported in part by the European Union, Area NMP.2013.1.1–2: Self-assembly of naturally occurring nanosystems: CellulosomePlus Project number: 604530, and by the EU Seventh Framework Programme (FP7 2007–2013) under the WallTraC project ...
Alves, Victor D, Barak, Yoav, Bayer, Edward A, Borovok, Ilya, Bule, Pedro, Cardoso, Vânia, Dassa, Bareket, Flint, Harry J, Fontes, Carlos M G A, Gilbert, Harry J, Hamberg, Yuval, Israeli-Ruimy, Vered, Jindou, Sadanari, Lamed, Raphael, Moraïs, Sarah, Najmudin, Shabir, Slutzki, Michal, White, Bryan A   +17 more
core   +1 more source

Expression of 6 × his-hGM-CSF fusion gene in larvae of silkworm (Bombyx mori) using recombinant baculovirus

浙江大学学报. 农业与生命科学版, 2005
Six × his-hGM-CSF fusion gene was inserted in silkworm baculovirus transfer vector pBacPAK8 to construct the recombinant transfer vector pBacPAKHis-GM-CSF.
ZHU Li-cheng, CHEN Jian, LIN Rong, JIN Yong-feng, ZHANG Yao-zhou   +4 more
doaj   +1 more source

IgG Fusion Proteins for Brain Delivery of Biologics via Blood–Brain Barrier Receptor-Mediated Transport

Pharmaceutics, 2022
The treatment of neurological disorders with large-molecule biotherapeutics requires that the therapeutic drug be transported across the blood–brain barrier (BBB). However, recombinant biotherapeutics, such as neurotrophins, enzymes, decoy receptors, and
Ruben J. Boado
doaj   +1 more source