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Interdisciplinary Medicine, Volume 4, Issue 3, May 2026.This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu +6 more
wiley +1 more source
, 2016 Simon R Lea,1,* Hannah J Metcalfe,1,* Jonathan Plumb,1 Christian Beerli,2 Chris Poll,3 Dave Singh,1 Katharine H Abbott-Banner3 1Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre,
Poll C +6 more
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Expression of the murine cytomegalovirus glycoprotein H by recombinant vaccinia virus [PDF]
, 1994 The sequence of the gene encoding glycoprotein H (gH) of murine cytomegalovirus (MCMV) strain Smith was determined and compared with the sequence of the gH of MCMV strain K181. Transcriptional analysis showed that gH is encoded by a large mRNA of 5.0 kb,
Rapp, Maria +4 more
core +1 more source
Advanced Science, Volume 13, Issue 24, 27 April 2026.In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu +9 more
wiley +1 more source
Chromatographic Analysis of Recombinant Lysostaphin Expressed in Escherichia coli [PDF]
, 2011 Lysostaphin (EC.3.4.24.75) is an extracellular glycylglycine endopeptidase produced exclusively by Staphylococcus simulans biovar staphylolyticus (ATCC 1362, NRRL B-2628).
Jennings, Claire
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Acid sphingomyelinase serum activity in control and ICU patients.
, 2014 This figure indicates median pre- and post-operative acid sphingomyelinase serum activity of the control group and median acid sphingomyelinase serum activity of the ICU group on admission.
Supandi Winoto-Morbach (501243) +8 more
core +1 more source
Apoptosis and signalling in acid sphingomyelinase deficient cells [PDF]
, 2000 Background Recent evidence suggests that the activation of a non-specific lipid scramblase during apoptosis induces the flipping of sphingomyelin from the cell surface to the cytoplasmic leaftet of the plasma membrane. Inner leaflet sphingomyelin is then
Sillence Dan J +2 more
core +1 more source
Recombinant gelatin and collagen from methylotrophic yeasts [PDF]
, 2002 Based on its structural role and compatibility within the human body, collagen is a commonly used biomaterial in medical applications, such as cosmetic surgery, wound treatment and tissue engineering.
Bruin, E.C., de
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Regulation of Arthritis Severity by the Acid Sphingomyelinase
, 2017 Background/Aims: Rheumatoid arthritis is a chronic autoimmune disease hallmarked by inflammation in synovial joints. Treatment is hampered by the lack of a cure and current disease-modifying drugs are associated with potentially severe toxicities ...
Stefanie Weber +10 more
core +1 more source
Expression and purification of recombinant human coagulation Factor VII fused to His-Tag through Gateway technology [PDF]
Background. Factor VII is a plasma glycoprotein that participates in the coagulation process leading to generation of fibrin. Construction, expression and purification of recombinant FVII fused to poly histidin tag through gateway technology ...
عدالتی فتح آباد, مهدی +6 more
core +1 more source