Results 231 to 240 of about 4,645,981 (305)

High-copy plasmid engineering enhances recombinant protein and antimicrobial peptide production in Corynebacterium glutamicum. [PDF]

Microb Cell Fact
Christmann J, Sommer A, Cao P, Kohlstedt M, Goldbeck O, Riedel CU, Becker J, Wittmann C.   +7 more
europepmc   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Multimodal High-Throughput Screening Raman Spectroscopy for Label-Free Single-Cell Characterization of Recombinant Protein Production in Baculovirus Expression Vector Systems. [PDF]

Anal Chem
Islam SMM, Worch K, Bali A, Latka I, Shiwani S, Popp J, Burse A, Schie IW.   +7 more
europepmc   +1 more source

Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy

Advanced Science, EarlyView.
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier, Megane Grah Kple, Julen Ariztia, Marion Leroux, Mathieu Moreau, Michael Claron, Maxime Cheveau, Adam Laouafa, Agnieszka Kownacka, Camille Petitot, John Simonet, Alexandre M. M. Dias, Sophie Poty, Charles Truillet, Bertrand Collin, Alexandra Oudot, Franck Denat   +16 more
wiley   +1 more source

Biotechnological Control of Hydrogel Properties via Recombinant Protein Molecular Weight Engineering. [PDF]

Macromol Biosci
Schlauch D, Ebbecke JP, von Alwörden AP, Solle D, Kara S, Lavrentieva A, Pepelanova I.   +6 more
europepmc   +1 more source

Comprehensive Lipidomic Analysis of Recombinant Protein-Producing CHO Cell Cultures: Insights for Media and Process Development. [PDF]

Mass Spectrom (Tokyo)
Chen S, Peh EKL, Mahfut FB, Yang YS, Ho YY, Ho YS.   +5 more
europepmc   +1 more source

Recombinant protein platform for high-throughput investigation of peptide-liposome interactions via fluorescence anisotropy depolarization. [PDF]

Commun Chem
Margaritakis A, Qian M, Johnson DH, Zeno WF, Ulmer TS, Chung PJ.   +5 more
europepmc   +1 more source

Microalgal colony blot: A simple and rapid method for direct detection of recombinant protein production in microalgae colonies. [PDF]

PLoS One
Torres-Tiji Y, Fields FJ, Mayfield SP.
europepmc   +1 more source

RP3Net: a deep learning model for predicting recombinant protein production in Escherichia coli. [PDF]

Bioinformatics
Tankhilevich E, Martinez Cuesta S, Barrett I, Berg C, Holmberg Schiavone L, Leach AR.   +5 more
europepmc   +1 more source

Development of an indirect ELISA based on a multi-epitope recombinant protein for antibody detection against African swine fever virus. [PDF]

Microbiol Spectr
Liu L, Chen Q, Yu L, Wu W, Mou S, Guo H, Tan C, Liu Q, Wang D, Chen H, Wang X.   +10 more
europepmc   +1 more source