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Recombinant proteins for genetic disease

Clinical Genetics, 1999
The era of molecular biology has led to the development of powerful tools capable of generating therapeutics for genetic disorders. Although there is much current emphasis placed on the development of ‘gene therapy’ for human disease, developments in the production and availability of recombinant proteins are likely to have a more substantial impact on
C S, Russell, L A, Clarke
openaire   +2 more sources

[Recombinant protein folding and production].

Medecine sciences : M/S, 2005
The biotechnology of recombinant protein production is now entering its most advanced stage, and the growth of industrial protein pharmaceuticals provides solid proof of this evolution. However, the systematic conversion of genetic information into a biologically active protein is constantly confronted by the fundamental problem of protein folding in ...
Betton, Jean-Michel, Chaffotte, Alain
openaire   +2 more sources

SCHEMA-Guided Protein Recombination

2004
Publisher Summary This chapter examines the different aspects of SCHEMA-guided protein recombination. SCHEMA is a scoring function that predicts which elements in homologous proteins can be swapped without disturbing the integrity of the structure. Using the structural coordinates of the parent proteins, SCHEMA identifies pairs of residues that are ...
Silberg, Jonathan J.   +2 more
openaire   +3 more sources

Recombinant Proteins in Vaccine Development

2003
The outer membrane of Neisseria meningitidis contains a variety of proteins with the potential for inclusion in new meningococcal vaccines (1). Studies on the vaccine potential of these proteins would be facilitated by the production of pure recombinant protein, free from other components of the Neisseria outer membrane.
M, Christodoulides   +2 more
openaire   +2 more sources

Recombinant Protein Expression in Escherichia coli (E.coli): What We Need to Know.

Current pharmaceutical design, 2018
S. Hayat   +3 more
semanticscholar   +1 more source

Advanced genetic strategies for recombinant protein expression in Escherichia coli

Journal of Biotechnology, 2005
Kim Kusk Mortensen, Hans Peter Sørensen
exaly  

Plant seeds as bioreactors for recombinant protein production

Biotechnology Advances, 2009
On Sun Lau, Samuel S M Sun
exaly  

Extracellular recombinant protein production from an Escherichia coli lpp deletion mutant

Biotechnology and Bioengineering, 2008
Rachel Chen, Hyun-Dong Shin
exaly  

Engineering a Catalytically Efficient Recombinant Protein Ligase.

Journal of the American Chemical Society, 2017
Renliang Yang   +5 more
semanticscholar   +1 more source

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