Results 241 to 250 of about 1,309,435 (302)

Sigma Factors as Potential Targets to Enhance Recombinant Protein Expression. [PDF]

Biotechnol Bioeng
Pohlen L, García E, Martínez LM, Flores N, Büchs J, Gosset G, Lara AR.   +6 more
europepmc   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

Improving recombinant protein secretion in <i>Aspergillus nidulans</i> by targeting the N-glycosylation machinery. [PDF]

Metab Eng Commun
Gerhardt JA, Rubio MV, Terrasan CRF, Wassano NS, Rodrigues A, Figueiredo FL, Antoniel EP, Contesini FJ, Dias AHS, Mortensen UH, Skaf MS, Damasio A.   +11 more
europepmc   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Induction conditions that promote the effect of glycerol on recombinant protein production in <i>Escherichia coli</i>. [PDF]

Biotechnol Rep (Amst)
Ojima Y, Saito H, Miyuki S, Fukunaga K, Tsuboi T, Azuma M.   +5 more
europepmc   +1 more source

A novel HVEM-Fc recombinant protein for lung cancer immunotherapy. [PDF]

J Exp Clin Cancer Res
Yao Y, Li B, Wang J, Chen C, Gao W, Li C.   +5 more
europepmc   +1 more source

Synthetic G-quadruplex components for predictable, precise two-level control of mammalian recombinant protein expression. [PDF]

Nucleic Acids Res
Pohle M, Curry E, Holden R, Gibson S, Brown A.   +4 more
europepmc   +1 more source

Advancing recombinant protein expression in Komagataella phaffii: opportunities and challenges. [PDF]

FEMS Yeast Res
Lv W, Cai M.
europepmc   +1 more source

Effect of recombinant protein production and release on microalgal fitness and the impact of environmental conditions for localized therapeutic delivery. [PDF]

J Biol Eng
Carvajal F, Vargas-Torres V, Becerra D, González-Quezada N, Egaña JT.   +4 more
europepmc   +1 more source

Enhancing recombinant protein production through Cre-loxP mediated chromosomal rearrangement evolution in Kluyveromyces marxianus. [PDF]

Commun Biol
Ren H, Zou Q, Song K, Yu Y, Zhou J, Mo W, Lu H.   +6 more
europepmc   +1 more source