Results 241 to 250 of about 1,327,803 (301)

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

Advanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan, Yunhui Wu, Feng Liu, Heng Fu, Yaqi Meng, Yingwei Ou, Xijing Yuan, Ian M. Adcock, Man Jia, Xiaoning Zeng, Xin Yao   +10 more
wiley   +1 more source

Estimation and validation of solubility of recombinant protein in E. coli strains via various advanced machine learning models. [PDF]

Sci Rep
Mahdi WA, Alhowyan A, Obaidullah AJ.
europepmc   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Design, Development and Immunogenic Evaluation of a Novel Lipl32 Recombinant Protein of Local Pathogenic Leptospira Serovars. [PDF]

Arch Razi Inst
Bakhshandeh N, Tebianian M, Khaki P, Esmaelizad M, Saadatmand S.   +4 more
europepmc   +1 more source

Advances in Subcellular Accumulation Design for Recombinant Protein Production in Tobacco. [PDF]

Biodes Res
Song SJ, Diao HP, Guo YF, Hwang I.
europepmc   +1 more source

A Novel Chitin-Based Purification System Using GAL1 Fusion Tags: Enhancing Recombinant Protein Production While Retaining Biological Activity. [PDF]

Microb Biotechnol
Tseng YK, Lu YH, Liu Y, Weng ZW, Lin YT, Tsai CH, Wu YL, Huang RN.   +7 more
europepmc   +1 more source

Immunogenicity of <i>Trypanosoma cruzi</i> Multi-Epitope Recombinant Protein as an Antigen Candidate for Chagas Disease Vaccine in Humans. [PDF]

Pathogens
Teh-Poot CF, Alfaro-Chacón A, Pech-Pisté LM, Rosado-Vallado ME, Asojo OA, Villanueva-Lizama LE, Dumonteil E, Cruz-Chan JV.   +7 more
europepmc   +1 more source

Combined fluorometric analysis of biliverdin and bilirubin by the recombinant protein HUG. [PDF]

MethodsX
Tramer F, Sist P, Cardenas-Perez R, Urbani R, Bortolussi G, Passamonti S.   +5 more
europepmc   +1 more source

Straightforward MALDI-TOF MS based screening approach for selection of recombinant protein-expressing <i>E. coli</i>. [PDF]

Biotechnol Notes
Kravtsov IN, Solovyev AI, Potemkina EA, Kartashova AV, Dmitrieva MA, Danilova KV, Tutykhina IL, Polyakov NB, Desinov VD, Egorova DA, Gintsburg AL.   +10 more
europepmc   +1 more source

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Recombinant Therapeutic Protein Vaccines

Protein & Peptide Letters, 2013
Recombinant technology has ushered in a new era for the pharmaceutical industry. Protein therapeutics, including plasma-derived products and antibodies obtained from the serum of infected patients, have been successfully adopted and utilized to treat various indications.
Satoshi, Ohtake, Tsutomu, Arakawa
openaire   +2 more sources