Results 11 to 20 of about 742,504 (289)

The renin-angiotensin-aldosterone system (RAAS) signaling pathways and cancer: foes versus allies

open access: yesCancer Cell International, 2023
The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental roles in cancer biology which influences cell growth, migration, death, and metastasis.
Bahareh Hassani   +2 more
doaj   +1 more source

Recombinant plasma proteins [PDF]

open access: yesVox Sanguinis, 2010
For almost 50 years, the fractionation of human plasma has been the sole possible source of a wide range of therapeutic proteins–such as coagulation factors, anticoagulants, immunoglobulins, and albumin – essential to the treatment of serious congenital or acquired bleeding or immunological diseases. In the last 20 years, the application of recombinant
openaire   +2 more sources

Prospective Use of Brown Spider Venom Toxins as Therapeutic and Biotechnological Inputs

open access: yesFrontiers in Molecular Biosciences, 2021
Brown spider (genus Loxosceles) venoms are mainly composed of protein toxins used for predation and defense. Bites of these spiders most commonly produce a local dermonecrotic lesion with gravitational spread, edema and hemorrhage, which together are ...
Luiza Helena Gremski   +10 more
doaj   +1 more source

Expression of recombinant 35 kDa fragment of VP2 protein of canine parvovirus using Escherichia coli expression system [PDF]

open access: yesVeterinary World, 2021
Background and Aim: Canine parvovirus (CPV) is one of the most common viral infections in dogs, causing acute hemorrhagic gastroenteritis and high mortality. Vaccination effectively prevents CPV infection.
Natnaree Inthong   +8 more
doaj   +1 more source

Noncontiguous SCHEMA Protein Recombination [PDF]

open access: yes, 2014
SCHEMA is a method of designing protein recombination libraries that contain a large fraction of functional proteins with a high degree of mutational diversity. In the previous chapter, we illustrated the method for designing libraries by swapping contiguous sequence elements.
Smith, Matthew A., Arnold, Frances H.
openaire   +3 more sources

Intronic regions of the human coagulation factor VIII gene harboring transcription factor binding sites with a strong bias towards the short-interspersed elements

open access: yesHeliyon, 2020
Increasing data show that intronic derived regulatory elements, such as transcription factor binding sites (TFBs), play key roles in gene regulation, and malfunction.
Aliakbar Haddad-Mashadrizeh   +2 more
doaj   +1 more source

Obtaining Recombinant Antigens for the Development of Serological Diagnosis of Marburg Fever

open access: yesПроблемы особо опасных инфекций, 2021
Aim. Production of recombinant viral antigens of the main immunodominant proteins: glycoprotein (GPΔMLD), nucleoprotein (NP) and matrix protein (VP40) of the Marburg virus, as well as the study of their antigenic and immunogenic properties.Materials and ...
N. V. Volkova   +6 more
doaj   +1 more source

Synthesis and characterization of smart stimuli-responsive herbal drug-encapsulated nanoniosome particles for efficient treatment of breast cancer

open access: yesNanotechnology Reviews, 2022
Extraction from the herbs was performed using the Soxhlet method. Various formula was synthesized for niosomes containing the extracts through thin film synthesis technique, and the most efficient formulation was selected.
Akhlaghi Milad   +8 more
doaj   +1 more source

Stimuli-Responsive Mesoporous Silica NPs as Non-viral Dual siRNA/Chemotherapy Carriers for Triple Negative Breast Cancer

open access: yesMolecular Therapy: Nucleic Acids, 2017
Triple negative breast cancer (TNBC) is the most aggressive and lethal subtype of breast cancer. It is associated with a very poor prognosis and intrinsically resistant to several conventional and targeted chemotherapy agents and has a 5-year survival ...
Behrad Darvishi   +2 more
doaj   +1 more source

The recent advancements in the early detection of cancer biomarkers by DNAzyme-assisted aptasensors

open access: yesJournal of Nanobiotechnology, 2022
Clinical diagnostics rely heavily on the detection and quantification of cancer biomarkers. The rapid detection of cancer-specific biomarkers is of great importance in the early diagnosis of cancers and plays a crucial role in the subsequent treatments ...
Hossein Kamali   +5 more
doaj   +1 more source

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