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Industrial Challenges of Recombinant Proteins

2019
The use of recombinant DNA methods to produce large quantities of protein for therapeutic uses has revolutionized medicine. Industrial challenges for manufacture of biotherapeutic proteins are related to the characteristics of these proteins and the increasing quantities required to address needs of patients, worldwide. A brief overview of therapies in
Scott R, Rudge, Michael R, Ladisch
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Heavy Labeling of Recombinant Proteins

2007
Because of the cost of isotopic chemicals and heterologous proteins to produce, an economical 15N/13C isotopic labeling method is critically needed. Four protocols have been tested for the expression of Ovine interferon-tau in Pichia pastoris. 13C-glucose in place of 13C-glycerol as well as the need for 15N/13C-sources were evaluated during the growth ...
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Retro-secretion of recombinant proteins

Nature, 1989
The retroviral Gag protein can be used to package recombinant proteins produced by mammalian cell cultures. Protein products can then be isolated easily from the recombinant virions.
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Recombinant Human Milk Proteins

2006
Human milk provides proteins that benefit newborn infants. They not only provide amino acids, but also facilitate the absorption of nutrients, stimulate growth and development of the intestine, modulate immune function, and aid in the digestion of other nutrients. Breastfed infants have a lower prevalence of infections than formula-fed infants.
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Recombinant Proteins and Monoclonal Antibodies

2017
The human genome has become a subject of public interest, whilst the proteome remains the province of specialists. Less appreciated is the human glycoprotein (GP) repertoire (proteoglycome!); however, some 50% of open reading frame genes encode for proteins (P) that may accept the addition of N-linked and/or O-linked sugar chains (oligosaccharides). It
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Challenges and opportunities in the purification of recombinant tagged proteins

Biotechnology Advances, 2014
Christopher R Lowe, Ana Pina
exaly  

Green factory: Plants as bioproduction platforms for recombinant proteins

Biotechnology Advances, 2012
Pamela Weathers   +2 more
exaly  

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