Results 21 to 30 of about 1,100,263 (385)

Crosstalk between MUC1 and VEGF in angiogenesis and metastasis: a review highlighting roles of the MUC1 with an emphasis on metastatic and angiogenic signaling

open access: yesCancer Cell International, 2021
VEGF and its receptor family (VEGFR) members have unique signaling transduction system that play significant roles in most pathological processes, such as angiogenesis in tumor growth and metastasis.
Farnaz Khodabakhsh   +3 more
doaj   +1 more source

The renin-angiotensin-aldosterone system (RAAS) signaling pathways and cancer: foes versus allies

open access: yesCancer Cell International, 2023
The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental roles in cancer biology which influences cell growth, migration, death, and metastasis.
Bahareh Hassani   +2 more
doaj   +1 more source

Roles of the AtErcc1 protein in recombination [PDF]

open access: yesThe Plant Journal, 2004
SummaryAtercc1, the recently characterized Arabidopsis homologue of the Ercc1 (Rad10) protein, is a key component of nucleotide excision repair as part of a structure‐specific endonuclease which cleaves 5′ to UV photoproducts in DNA. This endonuclease also acts in removing overhanging non‐homologous DNA ‘tails’ in synapsed recombination intermediates ...
Dubest, Sandra   +2 more
openaire   +6 more sources

Recombination of Fragmented Proteins [PDF]

open access: yesChemistry & Biology, 2004
Directed evolution is a powerful method for generating novel molecules with desirable properties. In developing a new sensor to screen for protein-protein interactions, Tafelmeyer et al. report a clever strategy to evolve heterodimeric "split proteins" from a monomer in this issue of Chemistry & Biology.
openaire   +3 more sources

Isolation of recombinant antibodies directed against surface proteins of Clostridium difficile [PDF]

open access: yes, 2016
Clostridium difficile has emerged as an increasingly important nosocomial pathogen and the prime causative agent of antibiotic-associated diarrhoea and pseudomembranous colitis in humans.
Aitken, Robert, Shirvan, Ali Nazari
core   +3 more sources

A practical method for efficient and optimal production of Seleno‐methionine‐labeled recombinant protein complexes in the insect cells [PDF]

open access: yes, 2019
The use of Seleno‐methionine (SeMet) incorporated protein crystals for single or multi‐wavelength anomalous diffraction (SAD or MAD) to facilitate phasing has become almost synonymous with modern X‐ray crystallography.
Imasaki, Tsuyoshi   +2 more
core   +1 more source

Novel expression of Haemonchus contortus vaccine candidate aminopeptidase H11 using the free-living nematode Caenorhabditis elegans [PDF]

open access: yes, 2013
With the problem of parasitic nematode drug resistance increasing, vaccine development offers an alternative sustainable control approach. For some parasitic nematodes, native extracts enriched for specific proteins are highly protective.
Antonopoulos, A.   +8 more
core   +3 more sources

Prospective Use of Brown Spider Venom Toxins as Therapeutic and Biotechnological Inputs

open access: yesFrontiers in Molecular Biosciences, 2021
Brown spider (genus Loxosceles) venoms are mainly composed of protein toxins used for predation and defense. Bites of these spiders most commonly produce a local dermonecrotic lesion with gravitational spread, edema and hemorrhage, which together are ...
Luiza Helena Gremski   +10 more
doaj   +1 more source

Recombining DNA by Protein Swivels [PDF]

open access: yesStructure, 2011
Two new reports on serine recombinases, one of a crystal snapshot in an alternate rotational conformer poised for DNA cleavage (Keenholtz et al., 2011), and a second employing single-DNA molecule approaches (Bai et al., 2011), provide strong support for the subunit rotation model for exchanging DNA strands.
Meghan M. McLean, Reid C. Johnson
openaire   +3 more sources

Obtaining Recombinant Antigens for the Development of Serological Diagnosis of Marburg Fever

open access: yesПроблемы особо опасных инфекций, 2021
Aim. Production of recombinant viral antigens of the main immunodominant proteins: glycoprotein (GPΔMLD), nucleoprotein (NP) and matrix protein (VP40) of the Marburg virus, as well as the study of their antigenic and immunogenic properties.Materials and ...
N. V. Volkova   +6 more
doaj   +1 more source

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