Results 11 to 20 of about 797,107 (316)

Plant-Based Cell-Free Transcription and Translation of Recombinant Proteins [PDF]

open access: yes, 2022
113124Plant cell-free lysates contain all the cellular components of the protein biosynthesis machinery, providing an alternative to intact plant cells, tissues, and whole plants for the production of recombinant proteins. Cell-free lysates achieve rapid
Schillberg, Stefan   +3 more
core   +1 more source

Production of Recombinant Proteins by Agrobacterium-Mediated Transient Expression [PDF]

open access: yes, 2022
The agroinfiltration of plant tissue is a robust method that allows the rapid and transient expression of recombinant proteins. Using wild-type plants as biomass, agroinfiltration exploits the ability of plants to synthesize even complex multimeric ...
Schillberg, Stefan   +3 more
core   +1 more source

Improving Recombinant Protein Recovery from Plant Tissue Using Heat Precipitation [PDF]

open access: yes, 2022
147157Plants are increasingly viewed as suitable expression hosts for the production of recombinant proteins, especially when oxidative folding and/or posttranslational modification is essential for protein stability and functionality.
Spiegel, Holger
core   +1 more source

Plant Cell-Based Recombinant Antibody Manufacturing with a 200 L Orbitally Shaken Disposable Bioreactor [PDF]

open access: yes, 2022
S.161-172Tobacco BY-2 cells are an attractive platform for the manufacture of a variety of biopharmaceutical proteins, including antibodies. Here, we describe the scaled-up cultivation of human IgG-secreting BY-2 cells in a 200 L orbitally shaken ...
Rasche, S., Raven, N., Schillberg, S.
core   +1 more source

Improvement of downstream processing of recombinant proteins by means of genetic engineering [PDF]

open access: yes, 1993
Flaschel E, Friehs K. Improvement of downstream processing of recombinant proteins by means of genetic engineering. Biotechnology Advances. 1993;11(1):31-77.The rapid advancement of genetic engineering has allowed to produce an impressive number of ...
Flaschel, Erwin, Friehs, Karl
core   +2 more sources

The renin-angiotensin-aldosterone system (RAAS) signaling pathways and cancer: foes versus allies

open access: yesCancer Cell International, 2023
The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental roles in cancer biology which influences cell growth, migration, death, and metastasis.
Bahareh Hassani   +2 more
doaj   +1 more source

Recombination of Fragmented Proteins [PDF]

open access: yesChemistry & Biology, 2004
Directed evolution is a powerful method for generating novel molecules with desirable properties. In developing a new sensor to screen for protein-protein interactions, Tafelmeyer et al. report a clever strategy to evolve heterodimeric "split proteins" from a monomer in this issue of Chemistry & Biology.
openaire   +3 more sources

Recombinant plasma proteins [PDF]

open access: yesVox Sanguinis, 2010
For almost 50 years, the fractionation of human plasma has been the sole possible source of a wide range of therapeutic proteins–such as coagulation factors, anticoagulants, immunoglobulins, and albumin – essential to the treatment of serious congenital or acquired bleeding or immunological diseases. In the last 20 years, the application of recombinant
openaire   +2 more sources

Roles of the AtErcc1 protein in recombination [PDF]

open access: yesThe Plant Journal, 2004
SummaryAtercc1, the recently characterized Arabidopsis homologue of the Ercc1 (Rad10) protein, is a key component of nucleotide excision repair as part of a structure‐specific endonuclease which cleaves 5′ to UV photoproducts in DNA. This endonuclease also acts in removing overhanging non‐homologous DNA ‘tails’ in synapsed recombination intermediates ...
Dubest, Sandra   +2 more
openaire   +3 more sources

Prospective Use of Brown Spider Venom Toxins as Therapeutic and Biotechnological Inputs

open access: yesFrontiers in Molecular Biosciences, 2021
Brown spider (genus Loxosceles) venoms are mainly composed of protein toxins used for predation and defense. Bites of these spiders most commonly produce a local dermonecrotic lesion with gravitational spread, edema and hemorrhage, which together are ...
Luiza Helena Gremski   +10 more
doaj   +1 more source

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