Production of Recombinant Proteins by Agrobacterium-Mediated Transient Expression
, 2022 The agroinfiltration of plant tissue is a robust method that allows the rapid and transient expression of recombinant proteins. Using wild-type plants as biomass, agroinfiltration exploits the ability of plants to synthesize even complex multimeric ...
Schillberg, Stefan +3 more
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Next-generation version of recombinant human interferon-beta: A molecular dynamic simulation study
Informatics in Medicine Unlocked, 2022 The ability of recombinant human interferon beta-1b (IFNβ-1b) to elicit the production of anti-IFNβ-1b antibodies becomes a significant issue for interferon therapy in patients.
Mohadeseh Haji Abdolvahab +3 more
doaj +1 more source
Improvement of downstream processing of recombinant proteins by means of genetic engineering [PDF]
, 1993 Flaschel E, Friehs K. Improvement of downstream processing of recombinant proteins by means of genetic engineering. Biotechnology Advances. 1993;11(1):31-77.The rapid advancement of genetic engineering has allowed to produce an impressive number of ...
Flaschel, Erwin, Friehs, Karl
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Improving Recombinant Protein Recovery from Plant Tissue Using Heat Precipitation
, 2022 147157Plants are increasingly viewed as suitable expression hosts for the production of recombinant proteins, especially when oxidative folding and/or posttranslational modification is essential for protein stability and functionality.
Spiegel, Holger
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The renin-angiotensin-aldosterone system (RAAS) signaling pathways and cancer: foes versus allies
Cancer Cell International, 2023 The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental roles in cancer biology which influences cell growth, migration, death, and metastasis.
Bahareh Hassani +2 more
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Adjuvant-free immunization with hemagglutinin-Fc fusion proteins as an approach to influenza vaccines [PDF]
, 2011 The hemagglutinins (HAs) of human H1 and H3 influenza viruses and avian H5 influenza virus were produced as recombinant fusion proteins with the human immunoglobulin Fc domain.
Temperton, Nigel J. +24 more
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, 2022 S.161-172Tobacco BY-2 cells are an attractive platform for the manufacture of a variety of biopharmaceutical proteins, including antibodies. Here, we describe the scaled-up cultivation of human IgG-secreting BY-2 cells in a 200 L orbitally shaken ...
Rasche, S., Raven, N., Schillberg, S.
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Maltose-binding protein enhances secretion of recombinant human granzyme B accompanied by in vivo processing of a precursor MBP fusion protein [PDF]
, 2010 Background: The apoptosis-inducing serine protease granzyme B (GrB) is an important factor contributing to lysis of target cells by cytotoxic lymphocytes.
Wels, Winfried +14 more
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Prospective Use of Brown Spider Venom Toxins as Therapeutic and Biotechnological Inputs
Frontiers in Molecular Biosciences, 2021 Brown spider (genus Loxosceles) venoms are mainly composed of protein toxins used for predation and defense. Bites of these spiders most commonly produce a local dermonecrotic lesion with gravitational spread, edema and hemorrhage, which together are ...
Luiza Helena Gremski +10 more
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Recombination of Fragmented Proteins [PDF]
Chemistry & Biology, 2004 Directed evolution is a powerful method for generating novel molecules with desirable properties. In developing a new sensor to screen for protein-protein interactions, Tafelmeyer et al. report a clever strategy to evolve heterodimeric "split proteins" from a monomer in this issue of Chemistry & Biology.
openaire +3 more sources