Results 11 to 20 of about 1,112,418 (308)

The renin-angiotensin-aldosterone system (RAAS) signaling pathways and cancer: foes versus allies

open access: yesCancer Cell International, 2023
The renin-angiotensin-aldosterone system (RAAS), is an old system with new fundamental roles in cancer biology which influences cell growth, migration, death, and metastasis.
Bahareh Hassani   +2 more
doaj   +1 more source

Recombination of Fragmented Proteins [PDF]

open access: yesChemistry & Biology, 2004
Directed evolution is a powerful method for generating novel molecules with desirable properties. In developing a new sensor to screen for protein-protein interactions, Tafelmeyer et al. report a clever strategy to evolve heterodimeric "split proteins" from a monomer in this issue of Chemistry & Biology.
openaire   +3 more sources

Recombinant plasma proteins [PDF]

open access: yesVox Sanguinis, 2010
For almost 50 years, the fractionation of human plasma has been the sole possible source of a wide range of therapeutic proteins–such as coagulation factors, anticoagulants, immunoglobulins, and albumin – essential to the treatment of serious congenital or acquired bleeding or immunological diseases. In the last 20 years, the application of recombinant
openaire   +2 more sources

Ebola virus VP35 induces high-level production of recombinant TPL-2–ABIN-2–NF-κB1 p105 complex in co-transfected HEK-293 cells [PDF]

open access: yes, 2013
Activation of PKR (double-stranded-RNA-dependent protein kinase) by DNA plasmids decreases translation, and limits the amount of recombinant protein produced by transiently transfected HEK (human embryonic kidney)-293 cells.
Apostolaki   +47 more
core   +1 more source

Gonadotropins in the Russian Sturgeon: Their Role in Steroid Secretion and the Effect of Hormonal Treatment on Their Secretion. [PDF]

open access: yes, 2016
In the reproduction process of male and female fish, pituitary derived gonadotropins (GTHs) play a key role. To be able to specifically investigate certain functions of Luteinizing (LH) and Follicle stimulating hormone (FSH) in Russian sturgeon ...
Aizen, Joseph   +8 more
core   +12 more sources

Roles of the AtErcc1 protein in recombination [PDF]

open access: yesThe Plant Journal, 2004
SummaryAtercc1, the recently characterized Arabidopsis homologue of the Ercc1 (Rad10) protein, is a key component of nucleotide excision repair as part of a structure‐specific endonuclease which cleaves 5′ to UV photoproducts in DNA. This endonuclease also acts in removing overhanging non‐homologous DNA ‘tails’ in synapsed recombination intermediates ...
Dubest, Sandra   +2 more
openaire   +3 more sources

Prospective Use of Brown Spider Venom Toxins as Therapeutic and Biotechnological Inputs

open access: yesFrontiers in Molecular Biosciences, 2021
Brown spider (genus Loxosceles) venoms are mainly composed of protein toxins used for predation and defense. Bites of these spiders most commonly produce a local dermonecrotic lesion with gravitational spread, edema and hemorrhage, which together are ...
Luiza Helena Gremski   +10 more
doaj   +1 more source

Expression of recombinant 35 kDa fragment of VP2 protein of canine parvovirus using Escherichia coli expression system [PDF]

open access: yesVeterinary World, 2021
Background and Aim: Canine parvovirus (CPV) is one of the most common viral infections in dogs, causing acute hemorrhagic gastroenteritis and high mortality. Vaccination effectively prevents CPV infection.
Natnaree Inthong   +8 more
doaj   +1 more source

HIV-1 Gag Specific IgG Response in Mice Immunized with Vp22-Gag Vaccine Candidate [PDF]

open access: yes, 2017
Background : Stimulation of Gag-specific CD8+ T-cell response, associated with reduction in viremia, viral replication control, and slow disease progression. Effective CD8+ T cell response is also influenced by CD4+ T cells.
Bekti, H. S. (Heri)
core   +1 more source

Recombinant Protein Stability in Cyanobacteria [PDF]

open access: yesACS Synthetic Biology, 2021
The living cell possesses extraordinary molecular and biochemical mechanisms by which to recognize and efficiently remove foreign, damaged, or denatured proteins. This essential function has been a barrier to the overexpression of recombinant proteins in most expression systems. A notable exception is the overexpression in E.
Xianan Zhang   +3 more
openaire   +5 more sources

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