Results 231 to 240 of about 516,295 (311)

Cnidarian toxins: omics approaches and recombinant proteins. [PDF]

J Venom Anim Toxins Incl Trop Dis
Vega-Tamayo JE, Alcantar-Orozco EJ, Mendoza-Ramírez RA, Silva-Díaz LG, Aguilar-Salazar JA, Salvador-Aguilar DH, Rojas-Molina A.   +6 more
europepmc   +1 more source

Recombinant zein protein bodies for the encapsulation of therapeutic proteins

Orale Verabreichung ist aufgrund der Akzeptanz durch Patienten der bevorzugte Verabreichungsweg für Arzneimittel. Orale Impfstoffe haben den Vorteil, dass sie eine Schleimhautimmunität auslösen können. Schleimhautimmunität ist besonders wichtig, da dort häufig die Eintrittsstelle für Krankheitserreger liegt.
openaire  

IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals

Advanced Science, EarlyView.
Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li, Zexuan Zhang, Zihan Xie, Cheng Jin, Zhipeng Wang, Changwei Yuan, Jun Zhu, Jielin Tang, Mengzhen Li, Dingfeng Zou, Xinyu Mang, Jun Liu, Dingyao Chen, Qi Geng, Yan Lu, Ning Zhang, Shiying Miao, Jing Peng, Kai Li, Wei Song   +19 more
wiley   +1 more source

Klotho mitigates diquat-induced myocardial injury in rats by activating Nrf2/ARE-mediated suppression of oxidative stress. [PDF]

Am J Transl Res
Zeng R, Liang Y, Li T, Xu Z.
europepmc   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

A Human β-Defensin-Based Recombinant Protein DF₂-HSA Ameliorates Cytokine Storm. [PDF]

Cells
Du Y, Yu Z, Sheng W, Li Y, Hou L, Zheng Y, Liu X, Zhen Y.   +7 more
europepmc   +1 more source

Single-domain antibodies for brain targeting [PDF]

, 2014
Lalatsa, Katerina, Moreira Leite, Diana
core   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

Advanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang, Xu Chen, Haowei Xu, Zhiqi Zeng, Keyu Lu, Yu Mao, Qianru Lv, Hui Shi, Song Liu, Xian Shen, Chunyu Yin, Yang Yang, Yan Guo, Xingyun Wang, Rui Cheng   +14 more
wiley   +1 more source

Prokaryotic expression of the giant panda VEGFA gene and the preparation and characterization of its monoclonal antibodies. [PDF]

Vet Anim Sci
Liu X, Li F, Wang S, Zhang M, Hu X, Liu Y, Hou R, Cai K.   +7 more
europepmc   +1 more source